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Protein

High-affinity zinc uptake system membrane protein ZnuB

Gene

znuB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the high-affinity zinc uptake transport system.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Zinc transport

Keywords - Ligandi

Zinc

Enzyme and pathway databases

BioCyciEcoCyc:ZNUB-MONOMER.
ECOL316407:JW1848-MONOMER.
MetaCyc:ZNUB-MONOMER.

Protein family/group databases

TCDBi3.A.1.15.5. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
High-affinity zinc uptake system membrane protein ZnuB
Gene namesi
Name:znuB
Synonyms:yebI
Ordered Locus Names:b1859, JW1848
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12368. znuB.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 7PeriplasmicSequence analysis7
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Topological domaini29 – 53CytoplasmicSequence analysisAdd BLAST25
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Topological domaini75 – 83PeriplasmicSequence analysis9
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Topological domaini105 – 121CytoplasmicSequence analysisAdd BLAST17
Transmembranei122 – 142HelicalSequence analysisAdd BLAST21
Topological domaini143 – 177PeriplasmicSequence analysisAdd BLAST35
Transmembranei178 – 198HelicalSequence analysisAdd BLAST21
Topological domaini199 – 213CytoplasmicSequence analysisAdd BLAST15
Transmembranei214 – 234HelicalSequence analysisAdd BLAST21
Topological domaini235PeriplasmicSequence analysis1
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Topological domaini257 – 261CytoplasmicSequence analysis5

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001711611 – 261High-affinity zinc uptake system membrane protein ZnuBAdd BLAST261

Proteomic databases

PaxDbiP39832.
PRIDEiP39832.

Interactioni

Protein-protein interaction databases

BioGridi4260881. 6 interactors.
STRINGi511145.b1859.

Structurei

3D structure databases

ProteinModelPortaliP39832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FAV. Bacteria.
COG1108. LUCA.
HOGENOMiHOG000181429.
InParanoidiP39832.
KOiK09816.
OMAiGVFVVWR.
PhylomeDBiP39832.

Family and domain databases

Gene3Di1.10.3470.10. 1 hit.
InterProiIPR029022. ABC_BtuC-like.
IPR001626. ABC_TroCD.
[Graphical view]
PfamiPF00950. ABC-3. 1 hit.
[Graphical view]
SUPFAMiSSF81345. SSF81345. 1 hit.

Sequencei

Sequence statusi: Complete.

P39832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIELLFPGWL AGIMLACAAG PLGSFVVWRR MSYFGDTLAH ASLLGVAFGL
60 70 80 90 100
LLDVNPFYAV IAVTLLLAGG LVWLEKRPQL AIDTLLGIMA HSALSLGLVV
110 120 130 140 150
VSLMSNIRVD LMAYLFGDLL AVTPEDLISI AIGVVIVVAI LFWQWRNLLS
160 170 180 190 200
MTISPDLAFV DGVKLQRVKL LLMLVTALTI GVAMKFVGAL IITSLLIIPA
210 220 230 240 250
ATARRFARTP EQMAGVAVLV GMVAVTGGLT FSAVYDTPAG PSVVLCAALL
260
FILSMMKKQA S
Length:261
Mass (Da):27,729
Last modified:November 1, 1997 - v3
Checksum:i78382B2EAECE1490
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74929.1.
AP009048 Genomic DNA. Translation: BAA15667.1.
U38702 Genomic DNA. Translation: AAA81031.1.
M21298 Genomic DNA. No translation available.
PIRiC64948.
RefSeqiNP_416373.1. NC_000913.3.
WP_000571480.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74929; AAC74929; b1859.
BAA15667; BAA15667; BAA15667.
GeneIDi946372.
KEGGiecj:JW1848.
eco:b1859.
PATRICi32119041. VBIEscCol129921_1938.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74929.1.
AP009048 Genomic DNA. Translation: BAA15667.1.
U38702 Genomic DNA. Translation: AAA81031.1.
M21298 Genomic DNA. No translation available.
PIRiC64948.
RefSeqiNP_416373.1. NC_000913.3.
WP_000571480.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260881. 6 interactors.
STRINGi511145.b1859.

Protein family/group databases

TCDBi3.A.1.15.5. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP39832.
PRIDEiP39832.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74929; AAC74929; b1859.
BAA15667; BAA15667; BAA15667.
GeneIDi946372.
KEGGiecj:JW1848.
eco:b1859.
PATRICi32119041. VBIEscCol129921_1938.

Organism-specific databases

EchoBASEiEB2271.
EcoGeneiEG12368. znuB.

Phylogenomic databases

eggNOGiENOG4105FAV. Bacteria.
COG1108. LUCA.
HOGENOMiHOG000181429.
InParanoidiP39832.
KOiK09816.
OMAiGVFVVWR.
PhylomeDBiP39832.

Enzyme and pathway databases

BioCyciEcoCyc:ZNUB-MONOMER.
ECOL316407:JW1848-MONOMER.
MetaCyc:ZNUB-MONOMER.

Miscellaneous databases

PROiP39832.

Family and domain databases

Gene3Di1.10.3470.10. 1 hit.
InterProiIPR029022. ABC_BtuC-like.
IPR001626. ABC_TroCD.
[Graphical view]
PfamiPF00950. ABC-3. 1 hit.
[Graphical view]
SUPFAMiSSF81345. SSF81345. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiZNUB_ECOLI
AccessioniPrimary (citable) accession number: P39832
Secondary accession number(s): P76286
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.