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Protein

Transcription antiterminator LicT

Gene

licT

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Mediates positive regulation of the glucanase operon (licST) by functioning as an antiterminator factor of transcription. Prevents termination at terminator lic-t.

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription, DNA-templated Source: CACAO
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU39080-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription antiterminator LicT
Gene namesi
Name:licT
Ordered Locus Names:BSU39080
ORF Names:N15A
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Transcription antiterminator LicTPRO_0000204247Add
BLAST

Post-translational modificationi

Phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP39805.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021096.

Structurei

Secondary structure

1
277
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 86Combined sources
Beta strandi11 – 155Combined sources
Beta strandi21 – 255Combined sources
Beta strandi27 – 304Combined sources
Helixi41 – 433Combined sources
Beta strandi45 – 517Combined sources
Helixi57 – 593Combined sources
Helixi63 – 653Combined sources
Helixi68 – 8518Combined sources
Helixi92 – 10918Combined sources
Helixi119 – 1257Combined sources
Helixi127 – 14418Combined sources
Helixi150 – 16415Combined sources
Helixi170 – 19021Combined sources
Helixi199 – 21719Combined sources
Helixi227 – 2359Combined sources
Helixi237 – 25418Combined sources
Helixi260 – 27415Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1H99X-ray1.55A57-277[»]
1L1CNMR-A/B1-55[»]
1TLVX-ray1.95A57-274[»]
ProteinModelPortaliP39805.
SMRiP39805. Positions 1-55, 57-275.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP39805.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini65 – 170106PRD 1PROSITE-ProRule annotationAdd
BLAST
Domaini171 – 277107PRD 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 PRD domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CID. Bacteria.
COG3711. LUCA.
HOGENOMiHOG000223756.
InParanoidiP39805.
KOiK03488.
OMAiYPDEYAI.
OrthoDBiEOG6KT2T7.
PhylomeDBiP39805.

Family and domain databases

Gene3Di1.10.1790.10. 2 hits.
2.30.24.10. 1 hit.
InterProiIPR004341. CAT_RNA-bd_dom.
IPR011608. PRD.
IPR001550. Transcrpt_antitermin_CS.
[Graphical view]
PfamiPF03123. CAT_RBD. 1 hit.
PF00874. PRD. 2 hits.
[Graphical view]
SMARTiSM01061. CAT_RBD. 1 hit.
[Graphical view]
SUPFAMiSSF50151. SSF50151. 1 hit.
SSF63520. SSF63520. 2 hits.
PROSITEiPS00654. PRD_1. 1 hit.
PS51372. PRD_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39805-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIAKVINNN VISVVNEQGK ELVVMGRGLA FQKKSGDDVD EARIEKVFTL
60 70 80 90 100
DNKDVSEKFK TLLYDIPIEC MEVSEEIISY AKLQLGKKLN DSIYVSLTDH
110 120 130 140 150
INFAIQRNQK GLDIKNALLW ETKRLYKDEF AIGKEALVMV KNKTGVSLPE
160 170 180 190 200
DEAGFIALHI VNAELNEEMP NIINITKVMQ EILSIVKYHF KIEFNEESLH
210 220 230 240 250
YYRFVTHLKF FAQRLFNGTH MESQDDFLLD TVKEKYHRAY ECTKKIQTYI
260 270
EREYEHKLTS DELLYLTIHI ERVVKQA
Length:277
Mass (Da):32,317
Last modified:February 1, 1995 - v1
Checksum:iE494702FD9B4C4A4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti79 – 791S → H in BAA11696 (PubMed:8969509).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28340 Genomic DNA. Translation: CAA82194.1.
D83026 Genomic DNA. Translation: BAA11696.1.
AL009126 Genomic DNA. Translation: CAB15944.2.
X00754 Genomic DNA. Translation: CAA25326.1.
PIRiS47216.
RefSeqiNP_391787.2. NC_000964.3.
WP_003242598.1. NZ_JNCM01000034.1.

Genome annotation databases

EnsemblBacteriaiCAB15944; CAB15944; BSU39080.
GeneIDi937503.
KEGGibsu:BSU39080.
PATRICi18979874. VBIBacSub10457_4099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28340 Genomic DNA. Translation: CAA82194.1.
D83026 Genomic DNA. Translation: BAA11696.1.
AL009126 Genomic DNA. Translation: CAB15944.2.
X00754 Genomic DNA. Translation: CAA25326.1.
PIRiS47216.
RefSeqiNP_391787.2. NC_000964.3.
WP_003242598.1. NZ_JNCM01000034.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1H99X-ray1.55A57-277[»]
1L1CNMR-A/B1-55[»]
1TLVX-ray1.95A57-274[»]
ProteinModelPortaliP39805.
SMRiP39805. Positions 1-55, 57-275.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021096.

Proteomic databases

PaxDbiP39805.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15944; CAB15944; BSU39080.
GeneIDi937503.
KEGGibsu:BSU39080.
PATRICi18979874. VBIBacSub10457_4099.

Phylogenomic databases

eggNOGiENOG4105CID. Bacteria.
COG3711. LUCA.
HOGENOMiHOG000223756.
InParanoidiP39805.
KOiK03488.
OMAiYPDEYAI.
OrthoDBiEOG6KT2T7.
PhylomeDBiP39805.

Enzyme and pathway databases

BioCyciBSUB:BSU39080-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP39805.

Family and domain databases

Gene3Di1.10.1790.10. 2 hits.
2.30.24.10. 1 hit.
InterProiIPR004341. CAT_RNA-bd_dom.
IPR011608. PRD.
IPR001550. Transcrpt_antitermin_CS.
[Graphical view]
PfamiPF03123. CAT_RBD. 1 hit.
PF00874. PRD. 2 hits.
[Graphical view]
SMARTiSM01061. CAT_RBD. 1 hit.
[Graphical view]
SUPFAMiSSF50151. SSF50151. 1 hit.
SSF63520. SSF63520. 2 hits.
PROSITEiPS00654. PRD_1. 1 hit.
PS51372. PRD_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "LicT, a Bacillus subtilis transcriptional antiterminator protein of the BglG family."
    Schnetz K., Stuelke J., Gertz S., Krueger S., Krieg M., Hecker M., Rak B.
    J. Bacteriol. 178:1971-1979(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / BR151.
  2. "Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region."
    Yoshida K., Shindo K., Sano H., Seki S., Fujimura M., Yanai N., Miwa Y., Fujita Y.
    Microbiology 142:3113-3123(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / BGSC1A1.
  3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  4. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
    Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
    Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO 79.
  5. "The DNA sequence of the gene and genetic control sites for the excreted B. subtilis enzyme beta-glucanase."
    Murphy N., McConnell D.J., Cantwell B.A.
    Nucleic Acids Res. 12:5355-5367(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 193-277.

Entry informationi

Entry nameiLICT_BACSU
AccessioniPrimary (citable) accession number: P39805
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 17, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.