Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P39766

- PYRP_BACSU

UniProt

P39766 - PYRP_BACSU

Protein

Uracil permease

Gene

pyrP

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 2 (16 Jun 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Transport of uracil in the cell.

    GO - Molecular functioni

    1. transporter activity Source: InterPro

    GO - Biological processi

    1. transmembrane transport Source: InterPro

    Keywords - Biological processi

    Transport

    Enzyme and pathway databases

    BioCyciBSUB:BSU15480-MONOMER.

    Protein family/group databases

    TCDBi2.A.40.1.4. the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uracil permease
    Alternative name(s):
    Uracil transporter
    Gene namesi
    Name:pyrP
    Ordered Locus Names:BSU15480
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU15480. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 435435Uracil permeasePRO_0000165957Add
    BLAST

    Proteomic databases

    PaxDbiP39766.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU15480.

    Structurei

    3D structure databases

    ProteinModelPortaliP39766.
    SMRiP39766. Positions 7-421.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei17 – 3721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei42 – 6221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei67 – 8721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei91 – 11121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei122 – 14221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei161 – 18121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei191 – 21323HelicalSequence AnalysisAdd
    BLAST
    Transmembranei234 – 25421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei311 – 33121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei336 – 35621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei376 – 39621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei399 – 41921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2233.
    HOGENOMiHOG000038200.
    KOiK02824.
    OrthoDBiEOG6Z3KKZ.
    PhylomeDBiP39766.

    Family and domain databases

    InterProiIPR006042. Xan_ur_permease.
    IPR006043. Xant/urac/vitC.
    [Graphical view]
    PANTHERiPTHR11119. PTHR11119. 1 hit.
    PfamiPF00860. Xan_ur_permease. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00801. ncs2. 1 hit.
    PROSITEiPS01116. XANTH_URACIL_PERMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P39766-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKKKVNLGV RDVPTPFSWV SFSLQHLFAM FGSTILVPKL VGMSPAVALV    50
    TSGIGTLAYL LITKGQIPAY LGSSFAFISP IILVKATGGP GAAMVGAFLA 100
    GLVYGLIALL IRQLGTGWLM KILPPVVVGP VIIVIGLGLA STAVNMAMYA 150
    DPNASELVYS LKHFSVAGVT LAITIICAIF LRGFLSLIPV LIGIIGGYLF 200
    ALTQGIVNFQ PVLDAKWFAV PEFIIPFKDY SPSVTLGIAA AMVPVAFVTM 250
    SEHIGHQMVL SKVVGQDFIK KPGLHRSIMG DSVATILASL IGGPPTTTYG 300
    ENIGVLAITR VFSVFVIGGA AVIALCFGFI GKISALISSV PSAVMGGVSF 350
    LLFGIIASSG LRMLIDNKID YENNRNLIIT SVILVIGVGG AFIQVSQGGF 400
    QVSGMALAAI VGVILNLILP QAKEEQADTS EQHHI 435
    Length:435
    Mass (Da):45,452
    Last modified:June 16, 2009 - v2
    Checksum:i2EB735352A034D33
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti231 – 26030SPSVT…HQMVL → HRQLRSASQPQWFLSHLSQC QSISATNGAE in AAA21266. (PubMed:1709162)CuratedAdd
    BLAST
    Sequence conflicti271 – 2722KP → A in AAA21266. (PubMed:1709162)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M59757 Genomic DNA. Translation: AAA21266.1.
    AL009126 Genomic DNA. Translation: CAB13422.2.
    PIRiA38984. A57986.
    RefSeqiNP_389431.2. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB13422; CAB13422; BSU15480.
    GeneIDi936604.
    KEGGibsu:BSU15480.
    PATRICi18974903. VBIBacSub10457_1643.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M59757 Genomic DNA. Translation: AAA21266.1 .
    AL009126 Genomic DNA. Translation: CAB13422.2 .
    PIRi A38984. A57986.
    RefSeqi NP_389431.2. NC_000964.3.

    3D structure databases

    ProteinModelPortali P39766.
    SMRi P39766. Positions 7-421.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU15480.

    Protein family/group databases

    TCDBi 2.A.40.1.4. the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family.

    Proteomic databases

    PaxDbi P39766.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB13422 ; CAB13422 ; BSU15480 .
    GeneIDi 936604.
    KEGGi bsu:BSU15480.
    PATRICi 18974903. VBIBacSub10457_1643.

    Organism-specific databases

    GenoListi BSU15480. [Micado ]

    Phylogenomic databases

    eggNOGi COG2233.
    HOGENOMi HOG000038200.
    KOi K02824.
    OrthoDBi EOG6Z3KKZ.
    PhylomeDBi P39766.

    Enzyme and pathway databases

    BioCyci BSUB:BSU15480-MONOMER.

    Family and domain databases

    InterProi IPR006042. Xan_ur_permease.
    IPR006043. Xant/urac/vitC.
    [Graphical view ]
    PANTHERi PTHR11119. PTHR11119. 1 hit.
    Pfami PF00860. Xan_ur_permease. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00801. ncs2. 1 hit.
    PROSITEi PS01116. XANTH_URACIL_PERMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Functional organization and nucleotide sequence of the Bacillus subtilis pyrimidine biosynthetic operon."
      Quinn C.L., Stephenson B.T., Switzer R.L.
      J. Biol. Chem. 266:9113-9127(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism."
      Turner R.J., Lu Y., Switzer R.L.
      J. Bacteriol. 176:3708-3722(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION, CHARACTERIZATION.
    3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.
    4. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
      Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
      Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 231-260 AND 271-272.

    Entry informationi

    Entry nameiPYRP_BACSU
    AccessioniPrimary (citable) accession number: P39766
    Secondary accession number(s): P25982
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 100 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3