Reviewed, UniProtKB/Swiss-Prot P39755 (NDHF_BACSU)

Names and origin

Protein names

Recommended name:
    Probable NADH-quinone oxidoreductase subunit 5
    EC=1.6.99.5
Alternative name(s):
    NADH dehydrogenase subunit 5

Gene names

Name:	ndhF
Synonyms:	ybxE
Ordered Locus Names:	BSU01830

Organism

Bacillus subtilis [Complete proteome] [HAMAP]

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	NADH + quinone = NAD(+) + quinol.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the complex I subunit 5 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Ligand	NAD
Molecular function	Oxidoreductase
PTM	Quinone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled electron transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 505	505	Probable NADH-quinone oxidoreductase subunit 5		PRO_0000118225
Regions
	Transmembrane	9 – 29	21	Potential
	Transmembrane	37 – 57	21	Potential
	Transmembrane	68 – 88	21	Potential
	Transmembrane	123 – 143	21	Potential
	Transmembrane	162 – 182	21	Potential
	Transmembrane	204 – 224	21	Potential
	Transmembrane	232 – 252	21	Potential
	Transmembrane	259 – 279	21	Potential
	Transmembrane	303 – 323	21	Potential
	Transmembrane	355 – 375	21	Potential
	Transmembrane	410 – 430	21	Potential
	Transmembrane	446 – 466	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P39755-1 [UniParc]. Last modified November 1, 1995. Version 2. Checksum: B62D1EE3B6004358	FASTA	505	55,468
	10 20 30 40 50 60 MLVSLSLSSL LTLFFIMLMA SGISGLLFLH PRVPLSFVRI HIGILALPLL VSLLILANSG 70 80 90 100 110 120 VSGNVGPWHL DSLACLMTFF VLAIGFIIQR FSVRYLMGDR SYRKYFTLFT FTTGAASMTW 130 140 150 160 170 180 LSGDLRLMVL FWGATLVGLT LLIRLNSAWQ VASEAAKISG RLFLLSWFSL FFAMMWLFHA 190 200 210 220 230 240 TGQWQLSLVV TNESLAGLGE WERTGIQLLI VLAVIIPAAQ WPFQRWLVES IVAPTPVSAI 250 260 270 280 290 300 MHAGLVNAGG IILTRFSPLF HGGIASIILL LLASISVLIG TGISLVQVDY KRQLVGSTIG 310 320 330 340 350 360 QMGFMLIQCA LGAYIAAIIH LILHGLFKAT LFLQAGSAVG RHEVSTRTNE RTSYLWVMAG 370 380 390 400 410 420 RILSLVIGVA FWLTAPGDGY HLISALILGW SLSVSWDQLV AFGEGRIGRI AGLTVLGGAA 430 440 450 460 470 480 LVYFIIHHLF YKWLHTTIFQ SVQPPMSAVM IVVCLLLFGS ALGTWVARHR SSVFFAVLYL 490 500 WLVRLGEAKP KSVESHPDYL KQYIS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Diverse capacities for the adaptive response to DNA alkylation in Bacillus species and strains." Morohoshi F., Munakata N. Mutat. Res. 337:97-110(1995) [PubMed: 7565865] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"Sequence analysis of the 70kb region between 17 and 23 degree of the Bacillus subtilis chromosome." Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H. Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[4]	Morohoshi F., Munakata N. Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-91. Strain: 168.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U28323 Genomic DNA. Translation: AAA70186.1. AB006424 Genomic DNA. Translation: BAA33076.1. Z99104 Genomic DNA. Translation: CAB11959.1. D21197 Genomic DNA. Translation: BAA21007.1.
PIR	C69666.
RefSeq	NP_388064.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	938593.
GenomeReviews	Gene locus BSU01830 in contig AL009126_GR.
KEGG	bsu:BSU01830.
NMPDR	fig|224308.1.peg.183.
Organism-specific databases
SubtiList	BG10949. ndhF. [Micado]
CMR	Search...
Phylogenomic databases
HOGENOM	P39755.
Enzyme and pathway databases
BioCyc	BSUB224308:BSU0183-MON.
Family and domain databases
InterPro	IPR003916. NADHub_OxRdtase_5. IPR001750. Oxidored_q1. [Graphical view]
Pfam	PF00361. Oxidored_q1. 1 hit. [Graphical view]
PRINTS	PR01434. NADHDHGNASE5.
ProtoNet	Search...

Entry information

Entry name

NDHF_BACSU

Accession

Primary (citable) accession number: P39755

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)