P39724 (AIM1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Altered inheritance of mitochondria protein 1

Gene names

Name:	AIM1
Ordered Locus Names:	YAL046C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	118 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Disruption phenotype	Increases frequency of mitochondrial genome loss. Ref.4
Miscellaneous	Present with 259 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the bolA/yrbA family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 118	118	Altered inheritance of mitochondria protein 1		PRO_0000201239

Sequences

	Sequence		Length	Mass (Da)
	P39724 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 244F5FF2052FF410	FASTA	118	13,356
	10 20 30 40 50 60 MKLPQTMLRS ISVKHVRWPR ILTGSKLWYS TQMAMTPEEK MITDKLQQEL EPEVCKVQDV 70 80 90 100 110 SGGCGSMFAI NITSKKFNGL SLIKQHQLVN RILRDDISRW HGLQLTTKKS TGKGPASS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae." Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K. Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[4]	"Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis." Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A. PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract] Cited for: DISRUPTION PHENOTYPE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U12980 Genomic DNA. Translation: AAC04985.1. BK006935 Genomic DNA. Translation: DAA06940.1.
PIR	S51973.
RefSeq	NP_009353.1. NM_001178191.1.
3D structure databases
ProteinModelPortal	P39724.
SMR	P39724. Positions 27-105.
ModBase	Search...
Protein-protein interaction databases
IntAct	P39724. 3 interactions.
MINT	MINT-2492096.
STRING	4932.YAL046C.
Proteomic databases
PaxDb	P39724.
PeptideAtlas	P39724.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YAL046C; YAL046C; YAL046C.
GeneID	851251.
KEGG	sce:YAL046C.
Organism-specific databases
CYGD	YAL046c.
SGD	S000000044. AIM1.
Phylogenomic databases
eggNOG	COG0271.
GeneTree	ENSGT00390000013048.
OMA	AINITSK.
OrthoDB	EOG4RBTVF.
Gene expression databases
Genevestigator	P39724.
GermOnline	YAL046C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002634. BolA. [Graphical view]
Pfam	PF01722. BolA. 1 hit. [Graphical view]
SUPFAM	SSF82657. BolA. 1 hit.
ProtoNet	Search...
Other
NextBio	968198.

Entry information

Entry name

AIM1_YEAST

Accession

Primary (citable) accession number: P39724
Secondary accession number(s): D6VPH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program