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P39721

- AIM2_YEAST

UniProt

P39721 - AIM2_YEAST

Protein

Protein AIM2

Gene

AIM2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. hydrolase activity Source: InterPro

    Enzyme and pathway databases

    BioCyciYEAST:G3O-28856-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein AIM2
    Alternative name(s):
    Altered inheritance rate of mitochondria protein 2
    Gene namesi
    Name:AIM2
    Ordered Locus Names:YAL049C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome I

    Organism-specific databases

    CYGDiYAL049c.
    SGDiS000000047. AIM2.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 246246Protein AIM2PRO_0000202423Add
    BLAST

    Proteomic databases

    MaxQBiP39721.
    PaxDbiP39721.
    PeptideAtlasiP39721.

    Expressioni

    Gene expression databases

    GenevestigatoriP39721.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself1EBI-20689,EBI-20689
    APP1P539332EBI-20689,EBI-28798

    Protein-protein interaction databases

    BioGridi31778. 6 interactions.
    DIPiDIP-2008N.
    IntActiP39721. 2 interactions.
    MINTiMINT-402861.
    STRINGi4932.YAL049C.

    Structurei

    3D structure databases

    ProteinModelPortaliP39721.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIM2 family.Curated

    Phylogenomic databases

    eggNOGiCOG0412.
    GeneTreeiENSGT00390000000183.
    HOGENOMiHOG000216630.
    OMAiLINACTI.
    OrthoDBiEOG7034TD.

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR002925. Dienelactn_hydro.
    [Graphical view]
    PfamiPF01738. DLH. 1 hit.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P39721-1 [UniParc]FASTAAdd to Basket

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    MASNQPGKCC FEGVCHDGTP KGRREEIFGL DTYAAGSTSP KEKVIVILTD    50
    VYGNKFNNVL LTADKFASAG YMVFVPDILF GDAISSDKPI DRDAWFQRHS 100
    PEVTKKIVDG FMKLLKLEYD PKFIGVVGYC FGAKFAVQHI SGDGGLANAA 150
    AIAHPSFVSI EEIEAIDSKK PILISAAEED HIFPANLRHL TEEKLKDNHA 200
    TYQLDLFSGV AHGFAARGDI SIPAVKYAKE KVLLDQIYWF NHFSNV 246
    Length:246
    Mass (Da):27,089
    Last modified:February 1, 1995 - v1
    Checksum:i607298D79EECEF5B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12980 Genomic DNA. Translation: AAC04982.1.
    AY692654 Genomic DNA. Translation: AAT92673.1.
    BK006935 Genomic DNA. Translation: DAA06937.1.
    PIRiS51970.
    RefSeqiNP_009350.1. NM_001178194.1.

    Genome annotation databases

    EnsemblFungiiYAL049C; YAL049C; YAL049C.
    GeneIDi851248.
    KEGGisce:YAL049C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12980 Genomic DNA. Translation: AAC04982.1 .
    AY692654 Genomic DNA. Translation: AAT92673.1 .
    BK006935 Genomic DNA. Translation: DAA06937.1 .
    PIRi S51970.
    RefSeqi NP_009350.1. NM_001178194.1.

    3D structure databases

    ProteinModelPortali P39721.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31778. 6 interactions.
    DIPi DIP-2008N.
    IntActi P39721. 2 interactions.
    MINTi MINT-402861.
    STRINGi 4932.YAL049C.

    Proteomic databases

    MaxQBi P39721.
    PaxDbi P39721.
    PeptideAtlasi P39721.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YAL049C ; YAL049C ; YAL049C .
    GeneIDi 851248.
    KEGGi sce:YAL049C.

    Organism-specific databases

    CYGDi YAL049c.
    SGDi S000000047. AIM2.

    Phylogenomic databases

    eggNOGi COG0412.
    GeneTreei ENSGT00390000000183.
    HOGENOMi HOG000216630.
    OMAi LINACTI.
    OrthoDBi EOG7034TD.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-28856-MONOMER.

    Miscellaneous databases

    NextBioi 968189.
    PROi P39721.

    Gene expression databases

    Genevestigatori P39721.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR002925. Dienelactn_hydro.
    [Graphical view ]
    Pfami PF01738. DLH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiAIM2_YEAST
    AccessioniPrimary (citable) accession number: P39721
    Secondary accession number(s): D6VPG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1800 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome I
      Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

    External Data

    Dasty 3