Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P39721 (AIM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein AIM2
Alternative name(s):
Altered inheritance rate of mitochondria protein 2
Gene names
Name:AIM2
Ordered Locus Names:YAL049C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Ref.4.

Miscellaneous

Present with 1800 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the AIM2 family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionhydrolase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

itself1EBI-20689,EBI-20689
APP1P539332EBI-20689,EBI-28798

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246Protein AIM2
PRO_0000202423

Sequences

Sequence LengthMass (Da)Tools
P39721 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 607298D79EECEF5B

FASTA24627,089
        10         20         30         40         50         60 
MASNQPGKCC FEGVCHDGTP KGRREEIFGL DTYAAGSTSP KEKVIVILTD VYGNKFNNVL 

        70         80         90        100        110        120 
LTADKFASAG YMVFVPDILF GDAISSDKPI DRDAWFQRHS PEVTKKIVDG FMKLLKLEYD 

       130        140        150        160        170        180 
PKFIGVVGYC FGAKFAVQHI SGDGGLANAA AIAHPSFVSI EEIEAIDSKK PILISAAEED 

       190        200        210        220        230        240 
HIFPANLRHL TEEKLKDNHA TYQLDLFSGV AHGFAARGDI SIPAVKYAKE KVLLDQIYWF 


NHFSNV 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae."
Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K.
Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U12980 Genomic DNA. Translation: AAC04982.1.
AY692654 Genomic DNA. Translation: AAT92673.1.
BK006935 Genomic DNA. Translation: DAA06937.1.
PIRS51970.
RefSeqNP_009350.1. NM_001178194.1.

3D structure databases

ProteinModelPortalP39721.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31778. 6 interactions.
DIPDIP-2008N.
IntActP39721. 2 interactions.
MINTMINT-402861.
STRING4932.YAL049C.

Proteomic databases

PaxDbP39721.
PeptideAtlasP39721.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYAL049C; YAL049C; YAL049C.
GeneID851248.
KEGGsce:YAL049C.

Organism-specific databases

CYGDYAL049c.
SGDS000000047. YAL049C.

Phylogenomic databases

eggNOGCOG0412.
GeneTreeENSGT00390000000183.
HOGENOMHOG000216630.
OMAASKRHES.
OrthoDBEOG7034TD.

Enzyme and pathway databases

BioCycYEAST:G3O-28856-MONOMER.

Gene expression databases

GenevestigatorP39721.

Family and domain databases

InterProIPR002925. Dienelactn_hydro.
[Graphical view]
PfamPF01738. DLH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio968189.
PROP39721.

Entry information

Entry nameAIM2_YEAST
AccessionPrimary (citable) accession number: P39721
Secondary accession number(s): D6VPG7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome I

Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families