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P39709

- SEO1_YEAST

UniProt

P39709 - SEO1_YEAST

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Protein

Probable transporter SEO1

Gene

SEO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Not known; suppressor of sulfoxide ethionine resistance.

GO - Molecular functioni

  1. transporter activity Source: SGD

GO - Biological processi

  1. transmembrane transport Source: InterPro
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-28866-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.37. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transporter SEO1
Gene namesi
Name:SEO1
Ordered Locus Names:YAL067C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome I

Organism-specific databases

CYGDiYAL067c.
SGDiS000000062. SEO1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 593593Probable transporter SEO1PRO_0000121368Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP39709.

Interactioni

Protein-protein interaction databases

BioGridi31762. 13 interactions.
DIPiDIP-8291N.
IntActiP39709. 1 interaction.
MINTiMINT-1354581.
STRINGi4932.YAL067C.

Structurei

3D structure databases

ProteinModelPortaliP39709.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 130130CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini152 – 17524ExtracellularSequence AnalysisAdd
BLAST
Topological domaini197 – 2004CytoplasmicSequence Analysis
Topological domaini222 – 23413ExtracellularSequence AnalysisAdd
BLAST
Topological domaini256 – 26510CytoplasmicSequence Analysis
Topological domaini287 – 30216ExtracellularSequence AnalysisAdd
BLAST
Topological domaini324 – 36340CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini385 – 41127ExtracellularSequence AnalysisAdd
BLAST
Topological domaini433 – 4386CytoplasmicSequence Analysis
Topological domaini460 – 4667ExtracellularSequence Analysis
Topological domaini488 – 49912CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini521 – 53212ExtracellularSequence AnalysisAdd
BLAST
Topological domaini554 – 59340CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei131 – 15121HelicalSequence AnalysisAdd
BLAST
Transmembranei176 – 19621HelicalSequence AnalysisAdd
BLAST
Transmembranei201 – 22121HelicalSequence AnalysisAdd
BLAST
Transmembranei235 – 25521HelicalSequence AnalysisAdd
BLAST
Transmembranei266 – 28621HelicalSequence AnalysisAdd
BLAST
Transmembranei303 – 32321HelicalSequence AnalysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence AnalysisAdd
BLAST
Transmembranei412 – 43221HelicalSequence AnalysisAdd
BLAST
Transmembranei439 – 45921HelicalSequence AnalysisAdd
BLAST
Transmembranei467 – 48721HelicalSequence AnalysisAdd
BLAST
Transmembranei500 – 52021HelicalSequence AnalysisAdd
BLAST
Transmembranei533 – 55321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00620000088258.
HOGENOMiHOG000179304.
InParanoidiP39709.
OMAiWKFWALL.
OrthoDBiEOG7QZGKW.

Family and domain databases

InterProiIPR011701. MFS.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.

Sequencei

Sequence statusi: Complete.

P39709-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE
60 70 80 90 100
TAENFITTTS EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD
110 120 130 140 150
EQEYRINEKE RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK
160 170 180 190 200
YLDTVNINNA YVSGMKEDLG FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK
210 220 230 240 250
LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL KAIRFFIGAF EAPSYLAYQY
260 270 280 290 300
LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL NGVNGLEGWR
310 320 330 340 350
WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT
360 370 380 390 400
GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK
410 420 430 440 450
SLKRYSIPKL NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI
460 470 480 490 500
IGNSILAAWD VAEGAKWFAF MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI
510 520 530 540 550
TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL KGFTFTACSA FCLSIWTFVV
560 570 580 590
LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS DEK
Length:593
Mass (Da):68,842
Last modified:February 1, 1995 - v1
Checksum:i6B7B1A2A7D5EAA44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1.
BK006935 Genomic DNA. Translation: DAA06920.1.
PIRiS51956.
RefSeqiNP_009333.1. NM_001178208.1.

Genome annotation databases

EnsemblFungiiYAL067C; YAL067C; YAL067C.
GeneIDi851230.
KEGGisce:YAL067C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1 .
BK006935 Genomic DNA. Translation: DAA06920.1 .
PIRi S51956.
RefSeqi NP_009333.1. NM_001178208.1.

3D structure databases

ProteinModelPortali P39709.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31762. 13 interactions.
DIPi DIP-8291N.
IntActi P39709. 1 interaction.
MINTi MINT-1354581.
STRINGi 4932.YAL067C.

Protein family/group databases

TCDBi 2.A.1.14.37. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YAL067C ; YAL067C ; YAL067C .
GeneIDi 851230.
KEGGi sce:YAL067C.

Organism-specific databases

CYGDi YAL067c.
SGDi S000000062. SEO1.

Phylogenomic databases

eggNOGi COG0477.
GeneTreei ENSGT00620000088258.
HOGENOMi HOG000179304.
InParanoidi P39709.
OMAi WKFWALL.
OrthoDBi EOG7QZGKW.

Enzyme and pathway databases

BioCyci YEAST:G3O-28866-MONOMER.

Miscellaneous databases

NextBioi 968141.

Gene expression databases

Genevestigatori P39709.

Family and domain databases

InterProi IPR011701. MFS.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view ]
Pfami PF07690. MFS_1. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  4. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSEO1_YEAST
AccessioniPrimary (citable) accession number: P39709
Secondary accession number(s): D6VPF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 29, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

External Data

Dasty 3