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P39709

- SEO1_YEAST

UniProt

P39709 - SEO1_YEAST

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Protein

Probable transporter SEO1

Gene
SEO1, YAL067C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Not known; suppressor of sulfoxide ethionine resistance.

GO - Molecular functioni

  1. transporter activity Source: SGD

GO - Biological processi

  1. transmembrane transport Source: InterPro
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-28866-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.37. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transporter SEO1
Gene namesi
Name:SEO1
Ordered Locus Names:YAL067C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome I

Organism-specific databases

CYGDiYAL067c.
SGDiS000000062. SEO1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 130130Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei131 – 15121Helical; Reviewed predictionAdd
BLAST
Topological domaini152 – 17524Extracellular Reviewed predictionAdd
BLAST
Transmembranei176 – 19621Helical; Reviewed predictionAdd
BLAST
Topological domaini197 – 2004Cytoplasmic Reviewed prediction
Transmembranei201 – 22121Helical; Reviewed predictionAdd
BLAST
Topological domaini222 – 23413Extracellular Reviewed predictionAdd
BLAST
Transmembranei235 – 25521Helical; Reviewed predictionAdd
BLAST
Topological domaini256 – 26510Cytoplasmic Reviewed prediction
Transmembranei266 – 28621Helical; Reviewed predictionAdd
BLAST
Topological domaini287 – 30216Extracellular Reviewed predictionAdd
BLAST
Transmembranei303 – 32321Helical; Reviewed predictionAdd
BLAST
Topological domaini324 – 36340Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei364 – 38421Helical; Reviewed predictionAdd
BLAST
Topological domaini385 – 41127Extracellular Reviewed predictionAdd
BLAST
Transmembranei412 – 43221Helical; Reviewed predictionAdd
BLAST
Topological domaini433 – 4386Cytoplasmic Reviewed prediction
Transmembranei439 – 45921Helical; Reviewed predictionAdd
BLAST
Topological domaini460 – 4667Extracellular Reviewed prediction
Transmembranei467 – 48721Helical; Reviewed predictionAdd
BLAST
Topological domaini488 – 49912Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei500 – 52021Helical; Reviewed predictionAdd
BLAST
Topological domaini521 – 53212Extracellular Reviewed predictionAdd
BLAST
Transmembranei533 – 55321Helical; Reviewed predictionAdd
BLAST
Topological domaini554 – 59340Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 593593Probable transporter SEO1PRO_0000121368Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP39709.

Interactioni

Protein-protein interaction databases

BioGridi31762. 13 interactions.
DIPiDIP-8291N.
IntActiP39709. 1 interaction.
MINTiMINT-1354581.
STRINGi4932.YAL067C.

Structurei

3D structure databases

ProteinModelPortaliP39709.
SMRiP39709. Positions 163-194.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00620000088258.
HOGENOMiHOG000179304.
OMAiWKFWALL.
OrthoDBiEOG7QZGKW.

Family and domain databases

InterProiIPR011701. MFS.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.

Sequencei

Sequence statusi: Complete.

P39709-1 [UniParc]FASTAAdd to Basket

« Hide

MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE    50
TAENFITTTS EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD 100
EQEYRINEKE RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK 150
YLDTVNINNA YVSGMKEDLG FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK 200
LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL KAIRFFIGAF EAPSYLAYQY 250
LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL NGVNGLEGWR 300
WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT 350
GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK 400
SLKRYSIPKL NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI 450
IGNSILAAWD VAEGAKWFAF MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI 500
TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL KGFTFTACSA FCLSIWTFVV 550
LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS DEK 593
Length:593
Mass (Da):68,842
Last modified:February 1, 1995 - v1
Checksum:i6B7B1A2A7D5EAA44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1.
BK006935 Genomic DNA. Translation: DAA06920.1.
PIRiS51956.
RefSeqiNP_009333.1. NM_001178208.1.

Genome annotation databases

EnsemblFungiiYAL067C; YAL067C; YAL067C.
GeneIDi851230.
KEGGisce:YAL067C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1 .
BK006935 Genomic DNA. Translation: DAA06920.1 .
PIRi S51956.
RefSeqi NP_009333.1. NM_001178208.1.

3D structure databases

ProteinModelPortali P39709.
SMRi P39709. Positions 163-194.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31762. 13 interactions.
DIPi DIP-8291N.
IntActi P39709. 1 interaction.
MINTi MINT-1354581.
STRINGi 4932.YAL067C.

Protein family/group databases

TCDBi 2.A.1.14.37. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YAL067C ; YAL067C ; YAL067C .
GeneIDi 851230.
KEGGi sce:YAL067C.

Organism-specific databases

CYGDi YAL067c.
SGDi S000000062. SEO1.

Phylogenomic databases

eggNOGi COG0477.
GeneTreei ENSGT00620000088258.
HOGENOMi HOG000179304.
OMAi WKFWALL.
OrthoDBi EOG7QZGKW.

Enzyme and pathway databases

BioCyci YEAST:G3O-28866-MONOMER.

Miscellaneous databases

NextBioi 968141.

Gene expression databases

Genevestigatori P39709.

Family and domain databases

InterProi IPR011701. MFS.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view ]
Pfami PF07690. MFS_1. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  4. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSEO1_YEAST
AccessioniPrimary (citable) accession number: P39709
Secondary accession number(s): D6VPF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

External Data

Dasty 3

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