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Protein

Probable transporter SEO1

Gene

SEO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Not known; suppressor of sulfoxide ethionine resistance.

GO - Molecular functioni

  1. transporter activity Source: SGD

GO - Biological processi

  1. transmembrane transport Source: InterPro
  2. transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-28866-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.37. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transporter SEO1
Gene namesi
Name:SEO1
Ordered Locus Names:YAL067C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome I

Organism-specific databases

CYGDiYAL067c.
SGDiS000000062. SEO1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 130130CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence AnalysisAdd
BLAST
Topological domaini152 – 17524ExtracellularSequence AnalysisAdd
BLAST
Transmembranei176 – 19621HelicalSequence AnalysisAdd
BLAST
Topological domaini197 – 2004CytoplasmicSequence Analysis
Transmembranei201 – 22121HelicalSequence AnalysisAdd
BLAST
Topological domaini222 – 23413ExtracellularSequence AnalysisAdd
BLAST
Transmembranei235 – 25521HelicalSequence AnalysisAdd
BLAST
Topological domaini256 – 26510CytoplasmicSequence Analysis
Transmembranei266 – 28621HelicalSequence AnalysisAdd
BLAST
Topological domaini287 – 30216ExtracellularSequence AnalysisAdd
BLAST
Transmembranei303 – 32321HelicalSequence AnalysisAdd
BLAST
Topological domaini324 – 36340CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence AnalysisAdd
BLAST
Topological domaini385 – 41127ExtracellularSequence AnalysisAdd
BLAST
Transmembranei412 – 43221HelicalSequence AnalysisAdd
BLAST
Topological domaini433 – 4386CytoplasmicSequence Analysis
Transmembranei439 – 45921HelicalSequence AnalysisAdd
BLAST
Topological domaini460 – 4667ExtracellularSequence Analysis
Transmembranei467 – 48721HelicalSequence AnalysisAdd
BLAST
Topological domaini488 – 49912CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei500 – 52021HelicalSequence AnalysisAdd
BLAST
Topological domaini521 – 53212ExtracellularSequence AnalysisAdd
BLAST
Transmembranei533 – 55321HelicalSequence AnalysisAdd
BLAST
Topological domaini554 – 59340CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 593593Probable transporter SEO1PRO_0000121368Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP39709.

Interactioni

Protein-protein interaction databases

BioGridi31762. 13 interactions.
DIPiDIP-8291N.
IntActiP39709. 1 interaction.
MINTiMINT-1354581.
STRINGi4932.YAL067C.

Structurei

3D structure databases

ProteinModelPortaliP39709.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00620000088258.
HOGENOMiHOG000179304.
InParanoidiP39709.
OMAiWKFWALL.
OrthoDBiEOG7QZGKW.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.

Sequencei

Sequence statusi: Complete.

P39709-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE
60 70 80 90 100
TAENFITTTS EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD
110 120 130 140 150
EQEYRINEKE RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK
160 170 180 190 200
YLDTVNINNA YVSGMKEDLG FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK
210 220 230 240 250
LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL KAIRFFIGAF EAPSYLAYQY
260 270 280 290 300
LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL NGVNGLEGWR
310 320 330 340 350
WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT
360 370 380 390 400
GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK
410 420 430 440 450
SLKRYSIPKL NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI
460 470 480 490 500
IGNSILAAWD VAEGAKWFAF MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI
510 520 530 540 550
TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL KGFTFTACSA FCLSIWTFVV
560 570 580 590
LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS DEK
Length:593
Mass (Da):68,842
Last modified:February 1, 1995 - v1
Checksum:i6B7B1A2A7D5EAA44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1.
BK006935 Genomic DNA. Translation: DAA06920.1.
PIRiS51956.
RefSeqiNP_009333.1. NM_001178208.1.

Genome annotation databases

EnsemblFungiiYAL067C; YAL067C; YAL067C.
GeneIDi851230.
KEGGisce:YAL067C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12980 Genomic DNA. Translation: AAC04968.1.
BK006935 Genomic DNA. Translation: DAA06920.1.
PIRiS51956.
RefSeqiNP_009333.1. NM_001178208.1.

3D structure databases

ProteinModelPortaliP39709.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31762. 13 interactions.
DIPiDIP-8291N.
IntActiP39709. 1 interaction.
MINTiMINT-1354581.
STRINGi4932.YAL067C.

Protein family/group databases

TCDBi2.A.1.14.37. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYAL067C; YAL067C; YAL067C.
GeneIDi851230.
KEGGisce:YAL067C.

Organism-specific databases

CYGDiYAL067c.
SGDiS000000062. SEO1.

Phylogenomic databases

eggNOGiCOG0477.
GeneTreeiENSGT00620000088258.
HOGENOMiHOG000179304.
InParanoidiP39709.
OMAiWKFWALL.
OrthoDBiEOG7QZGKW.

Enzyme and pathway databases

BioCyciYEAST:G3O-28866-MONOMER.

Miscellaneous databases

NextBioi968141.

Gene expression databases

GenevestigatoriP39709.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  4. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSEO1_YEAST
AccessioniPrimary (citable) accession number: P39709
Secondary accession number(s): D6VPF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.