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Protein

Glucose-1-phosphate adenylyltransferase

Gene

glgC

Organism
Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans.By similarity

Catalytic activityi

ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.7.27. 200.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphate adenylyltransferase (EC:2.7.7.27)
Alternative name(s):
ADP-glucose pyrophosphorylase
Short name:
ADPGlc PPase
ADP-glucose synthase
Gene namesi
Name:glgC
OrganismiRhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Taxonomic identifieri358 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001952721 – 420Glucose-1-phosphate adenylyltransferaseAdd BLAST420

Interactioni

Protein-protein interaction databases

STRINGi1050720.Agau_L100945.

Structurei

Secondary structure

1420
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi9 – 12Combined sources4
Beta strandi13 – 19Combined sources7
Helixi24 – 30Combined sources7
Beta strandi31 – 33Combined sources3
Helixi35 – 37Combined sources3
Beta strandi38 – 40Combined sources3
Turni41 – 43Combined sources3
Helixi48 – 56Combined sources9
Beta strandi61 – 66Combined sources6
Helixi71 – 80Combined sources10
Helixi86 – 88Combined sources3
Beta strandi91 – 95Combined sources5
Helixi110 – 115Combined sources6
Helixi118 – 124Combined sources7
Beta strandi127 – 135Combined sources9
Helixi143 – 151Combined sources9
Beta strandi155 – 164Combined sources10
Helixi167 – 170Combined sources4
Beta strandi171 – 176Combined sources6
Beta strandi180 – 188Combined sources9
Beta strandi201 – 212Combined sources12
Helixi213 – 220Combined sources8
Helixi240 – 244Combined sources5
Beta strandi247 – 251Combined sources5
Helixi252 – 255Combined sources4
Helixi273 – 282Combined sources10
Beta strandi285 – 287Combined sources3
Beta strandi310 – 312Combined sources3
Beta strandi321 – 324Combined sources4
Beta strandi332 – 335Combined sources4
Beta strandi337 – 340Combined sources4
Beta strandi354 – 360Combined sources7
Beta strandi371 – 377Combined sources7
Beta strandi388 – 391Combined sources4
Helixi393 – 399Combined sources7
Beta strandi400 – 402Combined sources3
Beta strandi408 – 410Combined sources3
Helixi412 – 416Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BRKX-ray2.10X1-420[»]
ProteinModelPortaliP39669.
SMRiP39669.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP39669.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107QQ4. Bacteria.
COG0448. LUCA.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39669-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKRVQPLA RDAMAYVLAG GRGSRLKELT DRRAKPAVYF GGKARIIDFA
60 70 80 90 100
LSNALNSGIR RIGVATQYKA HSLIRHLQRG WDFFRPERNE SFDILPASQR
110 120 130 140 150
VSETQWYEGT ADAVYQNIDI IEPYAPEYMV ILAGDHIYKM DYEYMLQQHV
160 170 180 190 200
DSGADVTIGC LEVPRMEATG FGVMHVNEKD EIIDFIEKPA DPPGIPGNEG
210 220 230 240 250
FALASMGIYV FHTKFLMEAV RRDAADPTSS RDFGKDIIPY IVEHGKAVAH
260 270 280 290 300
RFADSCVRSD FEHEPYWRDV GTIDAYWQAN IDLTDVVPDL DIYDKSWPIW
310 320 330 340 350
TYAEITPPAK FVHDDEDRRG SAVSSVVSGD CIISGAALNR SLLFTGVRAN
360 370 380 390 400
SYSRLENAVV LPSVKIGRHA QLSNVVIDHG VVIPEGLIVG EDPELDAKRF
410 420
RRTESGICLI TQSMIDKLDL
Length:420
Mass (Da):47,029
Last modified:February 1, 1995 - v1
Checksum:iF93F5E4E5996E698
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033856 Genomic DNA. Translation: AAD03473.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033856 Genomic DNA. Translation: AAD03473.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BRKX-ray2.10X1-420[»]
ProteinModelPortaliP39669.
SMRiP39669.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1050720.Agau_L100945.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107QQ4. Bacteria.
COG0448. LUCA.

Enzyme and pathway databases

UniPathwayiUPA00164.
BRENDAi2.7.7.27. 200.

Miscellaneous databases

EvolutionaryTraceiP39669.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLGC_RHIRD
AccessioniPrimary (citable) accession number: P39669
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.