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Protein

Putative aldehyde dehydrogenase YwdH

Gene

ywdH

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei210PROSITE-ProRule annotation1
Active sitei244PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBSUB:BSU37960-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase YwdHPROSITE-ProRule annotation (EC:1.2.1.3PROSITE-ProRule annotation)
Gene namesi
Name:ywdH
Ordered Locus Names:BSU37960
ORF Names:ipa-58r
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564451 – 456Putative aldehyde dehydrogenase YwdHAdd BLAST456

Proteomic databases

PaxDbiP39616

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100020501

Structurei

3D structure databases

ProteinModelPortaliP39616
SMRiP39616
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271515
InParanoidiP39616
KOiK00128
OMAiPLGCVLI
PhylomeDBiP39616

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
IPR012394 Aldehyde_DH_NAD(P)
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
PIRSFiPIRSF036492 ALDH, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

P39616-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSIPSIISK HKAYFAAGHT RPLESRLNIL RKLKQAVRTH EADLIAALYQ
60 70 80 90 100
DLHKSEQEAY STEIGIVLEE ISFVMKRLRK WSKPKRVKTP LTHLGSKSII
110 120 130 140 150
IPEPYGTVLV IAPWNYPLQL ALSPLIGAIA AGNTVVLKPS EYTPAVSAIL
160 170 180 190 200
SKLISSVFPT DYVAMAEGGP DVSTALLQQP FDYIFFTGSV AVGKIVMEAA
210 220 230 240 250
AKQLIPVTLE LGGKSPCIVH KDADIQLAAK RIVFGKFTNA GQTCIAPDYL
260 270 280 290 300
FVHEDIKTKL TEEMKRAIRE FYGPQPERNP QYGKIVSERH YQRLLSFLND
310 320 330 340 350
GIPLTGGQSD PNHHKIAPTI LEQVRDDSPV MQEEIFGPIL PLFTYRNIGE
360 370 380 390 400
VIEKVQSRPK PLALYLFTTN KEIERAVLGN LSFGGGCVND TLMHVATPYL
410 420 430 440 450
PFGGVGESGI GSYHGFDSFN TFTHKKSVVK QTNRFDFAFR YPSSKNGLRM

IRKILK
Length:456
Mass (Da):50,679
Last modified:June 16, 2009 - v2
Checksum:i78C8F36E6E6CB43B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2N → NS in CAA51614 (PubMed:7934828).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73124 Genomic DNA Translation: CAA51614.1
AL009126 Genomic DNA Translation: CAB15822.2
PIRiS39713
RefSeqiNP_391675.2, NC_000964.3
WP_003227441.1, NZ_JNCM01000034.1
WP_009968357.1, NZ_CM000487.1

Genome annotation databases

EnsemblBacteriaiCAB15822; CAB15822; BSU37960
GeneIDi937252
KEGGibsu:BSU37960
PATRICifig|224308.179.peg.4110

Similar proteinsi

Entry informationi

Entry nameiALDH2_BACSU
AccessioniPrimary (citable) accession number: P39616
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 16, 2009
Last modified: April 25, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health