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Protein

D-alanine--poly(phosphoribitol) ligase subunit 2

Gene

dltC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA.UniRule annotation

Catalytic activityi

ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate).UniRule annotation

Pathwayi: lipoteichoic acid biosynthesis

This protein is involved in the pathway lipoteichoic acid biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway lipoteichoic acid biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processCell wall biogenesis/degradation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU38520-MONOMER.
UniPathwayiUPA00556.

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--poly(phosphoribitol) ligase subunit 2UniRule annotation (EC:6.1.1.13UniRule annotation)
Alternative name(s):
D-alanyl carrier proteinUniRule annotation
Short name:
DCPUniRule annotation
Gene namesi
Name:dltCUniRule annotation
Ordered Locus Names:BSU38520
ORF Names:ipa-3r
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002130871 – 78D-alanine--poly(phosphoribitol) ligase subunit 2Add BLAST78

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei36O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Post-translational modificationi

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.UniRule annotation

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

PaxDbiP39579.
PRIDEiP39579.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100020796.

Structurei

Secondary structure

178
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 15Combined sources13
Helixi19 – 22Combined sources4
Turni28 – 32Combined sources5
Helixi36 – 50Combined sources15
Helixi56 – 58Combined sources3
Turni61 – 63Combined sources3
Helixi67 – 77Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4BPFX-ray1.01A1-78[»]
4BPGX-ray2.20A/B1-78[»]
4BPHX-ray1.80A1-78[»]
ProteinModelPortaliP39579.
SMRiP39579.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 78CarrierPROSITE-ProRule annotationAdd BLAST78

Sequence similaritiesi

Belongs to the DltC family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0236. LUCA.
HOGENOMiHOG000040491.
KOiK14188.
OMAiDEWNTPN.
PhylomeDBiP39579.

Family and domain databases

HAMAPiMF_00565. DltC. 1 hit.
InterProiView protein in InterPro
IPR003230. DltC.
IPR009081. PP-bd_ACP.
PANTHERiPTHR41270. PTHR41270. 1 hit.
PfamiView protein in Pfam
PF00550. PP-binding. 1 hit.
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR01688. dltC. 1 hit.
PROSITEiView protein in PROSITE
PS50075. CARRIER. 1 hit.

Sequencei

Sequence statusi: Complete.

P39579-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFKQEVLDV LAEVCQDDIV KENPDIEIFE EGLLDSFGTV ELLLAIENRF
60 70
DILVPITEFD RDVWNTPNNI VNQLSELK
Length:78
Mass (Da):9,009
Last modified:February 1, 1995 - v1
Checksum:i4A3F51C4A44CE8F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73124 Genomic DNA. Translation: CAA51559.1.
AL009126 Genomic DNA. Translation: CAB15878.1.
PIRiS39658.
RefSeqiNP_391731.1. NC_000964.3.
WP_003227325.1. NZ_JNCM01000034.1.

Genome annotation databases

EnsemblBacteriaiCAB15878; CAB15878; BSU38520.
GeneIDi937361.
KEGGibsu:BSU38520.
PATRICifig|224308.179.peg.4171.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73124 Genomic DNA. Translation: CAA51559.1.
AL009126 Genomic DNA. Translation: CAB15878.1.
PIRiS39658.
RefSeqiNP_391731.1. NC_000964.3.
WP_003227325.1. NZ_JNCM01000034.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4BPFX-ray1.01A1-78[»]
4BPGX-ray2.20A/B1-78[»]
4BPHX-ray1.80A1-78[»]
ProteinModelPortaliP39579.
SMRiP39579.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100020796.

Proteomic databases

PaxDbiP39579.
PRIDEiP39579.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15878; CAB15878; BSU38520.
GeneIDi937361.
KEGGibsu:BSU38520.
PATRICifig|224308.179.peg.4171.

Phylogenomic databases

eggNOGiCOG0236. LUCA.
HOGENOMiHOG000040491.
KOiK14188.
OMAiDEWNTPN.
PhylomeDBiP39579.

Enzyme and pathway databases

UniPathwayiUPA00556.
BioCyciBSUB:BSU38520-MONOMER.

Miscellaneous databases

PROiPR:P39579.

Family and domain databases

HAMAPiMF_00565. DltC. 1 hit.
InterProiView protein in InterPro
IPR003230. DltC.
IPR009081. PP-bd_ACP.
PANTHERiPTHR41270. PTHR41270. 1 hit.
PfamiView protein in Pfam
PF00550. PP-binding. 1 hit.
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR01688. dltC. 1 hit.
PROSITEiView protein in PROSITE
PS50075. CARRIER. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDLTC_BACSU
AccessioniPrimary (citable) accession number: P39579
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 7, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.