UniProtKB - P39547 (UIP3_YEAST)
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Protein
ULP1-interacting protein 3
Gene
UIP3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 1695 molecules/cell in log phase SD medium.1 Publication
GO - Biological processi
- vesicle organization Source: GO_Central
Enzyme and pathway databases
BioCyci | YEAST:G3O-28878-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: ULP1-interacting protein 3Alternative name(s): DUP240 protein UIP3 |
Gene namesi | Name:UIP3 Ordered Locus Names:YAR027W ORF Names:FUN55 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YAR027W. |
SGDi | S000000075. UIP3. |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 51 – 71 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 73 – 93 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, Membrane, NucleusPathology & Biotechi
Disruption phenotypei
Members of the DUP240 multigene family are specific to S.cerevisiae sensu strictu. Cells lacking all 10 DUP240 proteins show no obvious alterations in mating, sporulation and cell growth.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000207528 | 1 – 235 | ULP1-interacting protein 3Add BLAST | 235 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Cross-linki | 11 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication | ||
Cross-linki | 218 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources |
Keywords - PTMi
Isopeptide bond, Ubl conjugationProteomic databases
MaxQBi | P39547. |
PaxDbi | P39547. |
PRIDEi | P39547. |
PTM databases
iPTMneti | P39547. |
Interactioni
Subunit structurei
Interacts with ULP1.1 Publication
Binary interactionsi
With | Entry | #Exp. | IntAct | Notes |
---|---|---|---|---|
TMEM79 | Q9BSE2 | 3 | EBI-20760,EBI-8649725 | From Homo sapiens. |
Protein-protein interaction databases
BioGridi | 31806. 100 interactors. |
DIPi | DIP-2031N. |
IntActi | P39547. 56 interactors. |
MINTi | P39547. |
STRINGi | 4932.YAR027W. |
Family & Domainsi
Sequence similaritiesi
Belongs to the DUP/COS family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
GeneTreei | ENSGT00390000017646. |
HOGENOMi | HOG000000896. |
InParanoidi | P39547. |
OrthoDBi | EOG092C44UO. |
Family and domain databases
InterProi | View protein in InterPro IPR001142. DUP/COS. |
Pfami | View protein in Pfam PF00674. DUP. 1 hit. |
i Sequence
Sequence statusi: Complete.
P39547-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQTPSENTDV KLDTLDEPSA HLIEENVALP EDTFNSYWSY ILNEIARCKP
60 70 80 90 100
LMIMFLIPVC LVLLITFFHD IKGILVFLVI SLILSIIILL IGITAFVSET
110 120 130 140 150
LNKGFIIKLL VEVITRKPAV GGKEWRIIAY NMNQYLFDHG IWHTPYYFFC
160 170 180 190 200
EHRCHKFFKS LIKQTRSNAH LSSPTNGAEN TQSNTPAKEV SNEMVKPYIF
210 220 230
SSDPVLEAYL IKAAEIHKEA EFEYWRKQYP EVDLP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L28920 Genomic DNA. Translation: AAC09489.1. BK006935 Genomic DNA. Translation: DAA06999.1. |
PIRi | S53479. |
RefSeqi | NP_009414.1. NM_001178221.1. |
Genome annotation databases
EnsemblFungii | YAR027W; YAR027W; YAR027W. |
GeneIDi | 851279. |
KEGGi | sce:YAR027W. |
Similar proteinsi
Entry informationi
Entry namei | UIP3_YEAST | |
Accessioni | P39547Primary (citable) accession number: P39547 Secondary accession number(s): D6VPM9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | March 28, 2018 | |
This is version 131 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |