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P39542 (YJT3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized transporter YJL193W
Gene names
Ordered Locus Names:YJL193W
ORF Names:J0349
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the TPT transporter family.

Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processtransport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Uncharacterized transporter YJL193W
PRO_0000206786

Regions

Topological domain1 – 1212Cytoplasmic Potential
Transmembrane13 – 3321Helical; Potential
Topological domain34 – 5017Extracellular Potential
Transmembrane51 – 7121Helical; Potential
Topological domain72 – 10332Cytoplasmic Potential
Transmembrane104 – 12421Helical; Potential
Topological domain125 – 13410Extracellular Potential
Transmembrane135 – 15521Helical; Potential
Topological domain156 – 16510Cytoplasmic Potential
Transmembrane166 – 18621Helical; Potential
Topological domain187 – 20620Extracellular Potential
Transmembrane207 – 22721Helical; Potential
Topological domain228 – 27144Cytoplasmic Potential
Transmembrane272 – 29221Helical; Potential
Topological domain293 – 35361Extracellular Potential
Transmembrane354 – 37421Helical; Potential
Topological domain375 – 40228Cytoplasmic Potential

Amino acid modifications

Modified residue2471Phosphoserine Ref.5 Ref.6

Sequences

Sequence LengthMass (Da)Tools
P39542 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 3C8A1C2BFEB70F2A

FASTA40245,937
        10         20         30         40         50         60 
MFQQLSASIR HNAHIIFLCI SWYFISSLAS QVTKQVLTVC PLPLFLGEFQ FIYTAVLAWF 

        70         80         90        100        110        120 
TCYIAYSFPG FYRIFPNGTF PEYYIDDRET SRAARKESKL SSLIIPPSKP ILQTVLPLGL 

       130        140        150        160        170        180 
FQFVGKYFGH TATSLVPVST VASIKTLSPM FILLLQKILK ISTLKITLTL IFSLCTLVLG 

       190        200        210        220        230        240 
VWIIVQEDNR SPASSNELRE FSKYGVICAM ISMFIFVLQN IYGKTVFTYR SQTDESQSNS 

       250        260        270        280        290        300 
GFSRQESPLP LYEKLDEKLV AKKKPKSYDK LTLMIYISLV GFCLSFGWFI TLEFPVLFRY 

       310        320        330        340        350        360 
FFQINSSSTV IKAFPVSLFL LNGTFHFIQA MITFHLLGEV STLTYSIANL MKRFAIIAVS 

       370        380        390        400 
WVFIGRRITW LQVFGLVLNT LGLFLYERCT SQSKIKAKIR PE

« Hide

References

« Hide 'large scale' references
[1]"The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes."
Purnelle B., Coster F., Goffeau A.
Yeast 10:1235-1249(1994) [PubMed: 7754713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
[5]"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases."
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247, MASS SPECTROMETRY.
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X77688 Genomic DNA. Translation: CAA54767.1.
Z49468 Genomic DNA. Translation: CAA89488.1.
BK006943 Genomic DNA. Translation: DAA08614.1.
PIRS46641.
RefSeqNP_012342.1. NM_001181626.1.

3D structure databases

ProteinModelPortalP39542.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-7379N.
MINTMINT-1365208.
STRINGP39542.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL193W; YJL193W; YJL193W.
GeneID853246.
KEGGsce:YJL193W.
NMPDRfig|4932.3.peg.3306.

Organism-specific databases

CYGDYJL193w.
SGDS000003729. YJL193W.

Phylogenomic databases

eggNOGfuNOG04957.
GeneTreeEFGT00050000001387.
HOGENOMHBG202245.
OMAYDKLTLM.
OrthoDBEOG466ZW4.

Gene expression databases

ArrayExpressP39542.
GenevestigatorP39542.
GermOnlineYJL193W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR004853. DUF250.
[Graphical view]
KOK15283.
PfamPF03151. TPT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio973481.

Entry information

Entry nameYJT3_YEAST
AccessionPrimary (citable) accession number: P39542
Secondary accession number(s): D6VVZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: December 14, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents