Reviewed, UniProtKB/Swiss-Prot P39535 (YJT8_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized transporter YJL198W

Gene names

Ordered Locus Names:	YJL198W
ORF Names:	J0336

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	881 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Miscellaneous	Present with 3430 molecules/cell in log phase SD medium. Ref.3
Sequence similarities	Belongs to the citM (TC 2.A.11) transporter family. [View classification] Contains 1 SPX domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphate transport Inferred from genetic interaction. Source: SGD sodium ion transport Inferred from electronic annotation. Source: InterPro transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate transmembrane transporter activity Inferred from genetic interaction. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 881	881	Uncharacterized transporter YJL198W		PRO_0000172518
Regions
	Transmembrane	417 – 437	21	Potential
	Transmembrane	456 – 476	21	Potential
	Transmembrane	493 – 513	21	Potential
	Transmembrane	514 – 534	21	Potential
	Transmembrane	539 – 559	21	Potential
	Transmembrane	581 – 601	21	Potential
	Transmembrane	663 – 683	21	Potential
	Transmembrane	691 – 711	21	Potential
	Transmembrane	718 – 738	21	Potential
	Transmembrane	758 – 778	21	Potential
	Transmembrane	805 – 825	21	Potential
	Transmembrane	854 – 874	21	Potential
	Domain	1 – 288	288	SPX

Sequences

	Sequence		Length	Mass (Da)
	P39535-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: BB4466BC4D176714	FASTA	881	97,689
	10 20 30 40 50 60 MRFSHFLKYN AVPEWQNHYM DYSELKNLIY TLQTDELQVG DNEEGFGAGK SSNITDRFKN 70 80 90 100 110 120 KFSFKNAKED TSSGMNKDAG IVEETIELRE LPTAQTVAAK PSPFRRMKEK IFYKRRSSSA 130 140 150 160 170 180 SSVSSTANEN LQLDTYDTFV GDLTAEKQKV DDFYKRTEAK FYDKFDALVK DLKKIGVIEY 190 200 210 220 230 240 DIDDDTLFNE PIASTNDEVP PLDLDDDEDD DEFYDDQSNI EDNTALLHHS QYNIKSQKKS 250 260 270 280 290 300 LLKKSIVNLY IDLCQLKSFI ELNRIGFAKI TKKSDKVLHL NTRTELIESE QFFKDTYAFQ 310 320 330 340 350 360 AETIELLNSK ISQLVTFYAR ITDRPHNISH SKQELKSYLH DHIVWERSNT WKDMLGLLSQ 370 380 390 400 410 420 ADELTPKETE YNANKLVGKL DLEYYRWPLP RPINLKFTSI NNVALPKLFF TKKAYKIYFI 430 440 450 460 470 480 ILVTGLLLGI KTFNDAAQHR CMALVECVAF LWASEAIPLH ITAFLVPLLV VLFKVLKTSD 490 500 510 520 530 540 GAIMSAASAS SEILAAMWSS TIMILLAGFT LGEVLAQYNI AKVLASWLLA FAGCKPRNVL 550 560 570 580 590 600 LMAMCVVFFL SMWISNVAAP VLTYSLLSPL LDAMDADSPF AQALVLGVAL AANIGGMSSP 610 620 630 640 650 660 ISSPQNIISM SYLKPYGIGW GQFFAVALPS GILAMLLVWI LLFTTFKMNK TKLEKFKPIK 670 680 690 700 710 720 TKFTVKQYYI ITVTVATILL WCVESQIEGA FGSSGQIAII PIVLFFGTGL LSTQDLNAFP 730 740 750 760 770 780 WSIVILAMGG IALGKAVSSS GLLSTIAKAL QKKIENDGVF AILCIFGILM LVVGTFVSHT 790 800 810 820 830 840 VSAIIIIPLV QEVGDKLGNP KAAPILVFGC ALLSSCGMGL ASSGFPNVTA ISKVDRKGDR 850 860 870 880 YLSVMTFLTR GVPASILAFL CVITLGYGIM ASVVKGNATS A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes." Purnelle B., Coster F., Goffeau A. Yeast 10:1235-1249(1994) [PubMed: 7754713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X77688 Genomic DNA. Translation: CAA54759.1. Z49473 Genomic DNA. Translation: CAA89493.1.
PIR	S46633.
RefSeq	NP_012337.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P39535.
Genome annotation databases
Ensembl	YJL198W; YJL198W; YJL198W; Saccharomyces cerevisiae. [Genome view]
GeneID	853241.
KEGG	sce:YJL198W.
NMPDR	fig|4932.3.peg.3300.
Organism-specific databases
CYGD	YJL198w.
SGD	S000003734. PHO90.
Phylogenomic databases
HOGENOM	P39535.
OrthoDB	EOG9KM0K2
Gene expression databases
ArrayExpress	P39535.
Genevestigator	P39535.
GermOnline	YJL198W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001898. Na/sul_symport. IPR004331. SPX_N. [Graphical view]
Pfam	PF00939. Na_sulph_symp. 1 hit. PF03105. SPX. 1 hit. [Graphical view]
PROSITE	PS51382. SPX. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	973469.

Entry information

Entry name

YJT8_YEAST

Accession

Primary (citable) accession number: P39535

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	November 24, 2009
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)