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Protein

Low-affinity phosphate transporter PHO90

Gene

PHO90

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Low-affinity phosphate transporter involved in the control of cellular phosphate levels.2 Publications

GO - Molecular functioni

  • inorganic phosphate transmembrane transporter activity Source: SGD

GO - Biological processi

  • phosphate ion transport Source: SGD
  • polyphosphate metabolic process Source: SGD
  • regulation of phosphate transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31629-MONOMER.
BRENDAi3.6.3.27. 984.

Protein family/group databases

TCDBi2.A.47.2.3. the divalent anion:na(+) symporter (dass) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Low-affinity phosphate transporter PHO90
Gene namesi
Name:PHO90
Ordered Locus Names:YJL198W
ORF Names:J0336
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJL198W.
SGDiS000003734. PHO90.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Transmembranei456 – 476HelicalSequence analysisAdd BLAST21
Transmembranei493 – 513HelicalSequence analysisAdd BLAST21
Transmembranei514 – 534HelicalSequence analysisAdd BLAST21
Transmembranei539 – 559HelicalSequence analysisAdd BLAST21
Transmembranei581 – 601HelicalSequence analysisAdd BLAST21
Transmembranei663 – 683HelicalSequence analysisAdd BLAST21
Transmembranei691 – 711HelicalSequence analysisAdd BLAST21
Transmembranei718 – 738HelicalSequence analysisAdd BLAST21
Transmembranei758 – 778HelicalSequence analysisAdd BLAST21
Transmembranei805 – 825HelicalSequence analysisAdd BLAST21
Transmembranei854 – 874HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001725181 – 881Low-affinity phosphate transporter PHO90Add BLAST881

Proteomic databases

MaxQBiP39535.
PRIDEiP39535.

Expressioni

Inductioni

Expression is constitutive and independent of inorganic phosphate concentration and PHO4 activity.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi33566. 46 interactors.
MINTiMINT-4491371.

Structurei

3D structure databases

ProteinModelPortaliP39535.
SMRiP39535.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 288SPXPROSITE-ProRule annotationAdd BLAST288

Sequence similaritiesi

Contains 1 SPX domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00730000112809.
InParanoidiP39535.
KOiK14430.
OMAiHAYLEDC.
OrthoDBiEOG092C0UFE.

Family and domain databases

InterProiIPR004680. Cit_transptr-like_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF03600. CitMHS. 1 hit.
PF03105. SPX. 2 hits.
[Graphical view]
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39535-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFSHFLKYN AVPEWQNHYM DYSELKNLIY TLQTDELQVG DNEEGFGAGK
60 70 80 90 100
SSNITDRFKN KFSFKNAKED TSSGMNKDAG IVEETIELRE LPTAQTVAAK
110 120 130 140 150
PSPFRRMKEK IFYKRRSSSA SSVSSTANEN LQLDTYDTFV GDLTAEKQKV
160 170 180 190 200
DDFYKRTEAK FYDKFDALVK DLKKIGVIEY DIDDDTLFNE PIASTNDEVP
210 220 230 240 250
PLDLDDDEDD DEFYDDQSNI EDNTALLHHS QYNIKSQKKS LLKKSIVNLY
260 270 280 290 300
IDLCQLKSFI ELNRIGFAKI TKKSDKVLHL NTRTELIESE QFFKDTYAFQ
310 320 330 340 350
AETIELLNSK ISQLVTFYAR ITDRPHNISH SKQELKSYLH DHIVWERSNT
360 370 380 390 400
WKDMLGLLSQ ADELTPKETE YNANKLVGKL DLEYYRWPLP RPINLKFTSI
410 420 430 440 450
NNVALPKLFF TKKAYKIYFI ILVTGLLLGI KTFNDAAQHR CMALVECVAF
460 470 480 490 500
LWASEAIPLH ITAFLVPLLV VLFKVLKTSD GAIMSAASAS SEILAAMWSS
510 520 530 540 550
TIMILLAGFT LGEVLAQYNI AKVLASWLLA FAGCKPRNVL LMAMCVVFFL
560 570 580 590 600
SMWISNVAAP VLTYSLLSPL LDAMDADSPF AQALVLGVAL AANIGGMSSP
610 620 630 640 650
ISSPQNIISM SYLKPYGIGW GQFFAVALPS GILAMLLVWI LLFTTFKMNK
660 670 680 690 700
TKLEKFKPIK TKFTVKQYYI ITVTVATILL WCVESQIEGA FGSSGQIAII
710 720 730 740 750
PIVLFFGTGL LSTQDLNAFP WSIVILAMGG IALGKAVSSS GLLSTIAKAL
760 770 780 790 800
QKKIENDGVF AILCIFGILM LVVGTFVSHT VSAIIIIPLV QEVGDKLGNP
810 820 830 840 850
KAAPILVFGC ALLSSCGMGL ASSGFPNVTA ISKVDRKGDR YLSVMTFLTR
860 870 880
GVPASILAFL CVITLGYGIM ASVVKGNATS A
Length:881
Mass (Da):97,689
Last modified:February 1, 1995 - v1
Checksum:iBB4466BC4D176714
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77688 Genomic DNA. Translation: CAA54759.1.
Z49473 Genomic DNA. Translation: CAA89493.1.
BK006943 Genomic DNA. Translation: DAA08610.1.
PIRiS46633.
RefSeqiNP_012337.1. NM_001181631.1.

Genome annotation databases

EnsemblFungiiYJL198W; YJL198W; YJL198W.
GeneIDi853241.
KEGGisce:YJL198W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77688 Genomic DNA. Translation: CAA54759.1.
Z49473 Genomic DNA. Translation: CAA89493.1.
BK006943 Genomic DNA. Translation: DAA08610.1.
PIRiS46633.
RefSeqiNP_012337.1. NM_001181631.1.

3D structure databases

ProteinModelPortaliP39535.
SMRiP39535.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33566. 46 interactors.
MINTiMINT-4491371.

Protein family/group databases

TCDBi2.A.47.2.3. the divalent anion:na(+) symporter (dass) family.

Proteomic databases

MaxQBiP39535.
PRIDEiP39535.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJL198W; YJL198W; YJL198W.
GeneIDi853241.
KEGGisce:YJL198W.

Organism-specific databases

EuPathDBiFungiDB:YJL198W.
SGDiS000003734. PHO90.

Phylogenomic databases

GeneTreeiENSGT00730000112809.
InParanoidiP39535.
KOiK14430.
OMAiHAYLEDC.
OrthoDBiEOG092C0UFE.

Enzyme and pathway databases

BioCyciYEAST:G3O-31629-MONOMER.
BRENDAi3.6.3.27. 984.

Miscellaneous databases

PROiP39535.

Family and domain databases

InterProiIPR004680. Cit_transptr-like_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF03600. CitMHS. 1 hit.
PF03105. SPX. 2 hits.
[Graphical view]
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHO90_YEAST
AccessioniPrimary (citable) accession number: P39535
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3430 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.