Reviewed,
UniProtKB/Swiss-Prot P39531 (RCY1_YEAST)
Last modified
November 24, 2009.
Version 67.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Recyclin-1 | ||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 840 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Involved in recycling plasma membrane proteins internalized by endocytosis. Required for recycling of the v-SNARE SNC1. Ref.4 Ref.5 |
| Subunit structure | Interacts with SKP1. Ref.5 |
| Subcellular location | Note: Localized to sites of polarized growth. Ref.5 |
| Miscellaneous | Present with 2700 molecules/cell in log phase SD medium. Ref.6 |
| Sequence similarities | Contains 1 F-box domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Protein transport Transport |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | endocytosis Ref.4 Inferred from mutant phenotype. Source: SGD exocytosisInferred from electronic annotation. Source: InterPro protein transportInferred from electronic annotation. Source: UniProtKB-KW vesicle dockingInferred from electronic annotation. Source: InterPro |
| Cellular component | Golgi apparatus Inferred from direct assay. Source: SGD endosomeInferred from direct assay. Source: SGD site of polarized growth Ref.5Inferred from direct assay. Source: SGD |
| Molecular function | protein binding Ref.5 Inferred from mutant phenotype. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes." Purnelle B., Coster F., Goffeau A. Yeast 10:1235-1249(1994) [PubMed: 7754713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [2] | Purnelle B. Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION. |
| [3] | "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. Karpfinger-Hartl L.EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [4] | "The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae." Wiederkehr A., Avaro S., Prescianotto-Baschong C., Haguenauer-Tsapis R., Riezman H. J. Cell Biol. 149:397-410(2000) [PubMed: 10769031] [Abstract] Cited for: FUNCTION. |
| [5] | "Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast." Galan J.M., Wiederkehr A., Seol J.H., Haguenauer-Tsapis R., Deshaies R.J., Riezman H., Peter M. Mol. Cell. Biol. 21:3105-3117(2001) [PubMed: 11287615] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH SKP1. |
| [6] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [7] | "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-407, MASS SPECTROMETRY. |
| [8] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-407, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| X77688 Genomic DNA. Translation: CAA54753.1. Z49479 Genomic DNA. Translation: CAA89499.1. Z49480 Genomic DNA. Translation: CAA89501.1. | |
| PIR | S77615. |
| RefSeq | NP_012331.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:7247N. |
| IntAct | P39531. 7 interactions. |
| STRING | P39531. |
Genome annotation databases | |
| Ensembl | YJL204C; YJL204C; YJL204C; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 853226. |
| KEGG | sce:YJL204C. |
| NMPDR | fig|4932.3.peg.3294. |
Organism-specific databases | |
| CYGD | YJL204c. |
| SGD | S000003740. RCY1. |
Phylogenomic databases | |
| HOGENOM | P39531. |
| OMA | FTQEEIY |
| OrthoDB | EOG90031C |
Gene expression databases | |
| ArrayExpress | P39531. |
| Genevestigator | P39531. |
| GermOnline | YJL204C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR001810. F-box. IPR009976. Sec10. [Graphical view] |
| Pfam | PF00646. F-box. 1 hit. PF07393. Sec10. 1 hit. [Graphical view] |
| PROSITE | PS50181. FBOX. False negative. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 973434. |
Entry information
| Entry name | RCY1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P39531 Secondary accession number(s): P39530, P87193 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome X Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names |

Clusters with


