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P39465 (GPT_SULAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

EC=2.7.8.15
Alternative name(s):
GlcNAc-1-P transferase
Short name=G1PT
Short name=GPT
N-acetylglucosamine-1-phosphate transferase
Gene names
Name:gnpTA
Ordered Locus Names:Saci_0093
OrganismSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) [Complete proteome] [HAMAP]
Taxonomic identifier330779 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Enzyme regulation

Inhibited by tunicamycin By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the glycosyltransferase 4 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 328328Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
PRO_0000108766

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane48 – 6821Helical; Potential
Transmembrane78 – 9821Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane166 – 18621Helical; Potential
Transmembrane192 – 21221Helical; Potential
Transmembrane228 – 24821Helical; Potential
Transmembrane301 – 32121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P39465 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 01798FA2BD3297D9

FASTA32835,472
        10         20         30         40         50         60 
MLVSLLGILL SVIVGFVVTL ISTKWVIGLC KKRGFTGKDI NKLTKDDVPV LGGIGIVAGF 

        70         80         90        100        110        120 
VAGSFTFLLT SYNLSPGIEN VVVSILLSSL IIGFLGLLDD IFNISQATRA FLPIFASIPL 

       130        140        150        160        170        180 
ILYSVGHTII SIPFLGKVNF GILFYIIILP ATLTITANAF NMLEGLNGLG AGMGLIMALA 

       190        200        210        220        230        240 
LAYIGLKSGG TSFYAGIVSI ILASVLFGFL IFNFYPAKTF PGNIGTYFIG SVIGSIGISG 

       250        260        270        280        290        300 
YMYTALFFLY LPYVIEFVLK AKTRFKGVSF GKIDDQGYLH WDSKPNSLTH IVMRIGKFKE 

       310        320 
YHIVLIIWGI EILFAILAVV FQTVTITI 

« Hide

References

« Hide 'large scale' references
[1]"Archaebacterial ether-linked lipid biosynthetic gene. Expression cloning, sequencing, and characterization of geranylgeranyl-diphosphate synthase."
Ohnuma S., Suzuki M., Nishino T.
J. Biol. Chem. 269:14792-14797(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.
[2]"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota."
Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.
J. Bacteriol. 187:4992-4999(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D28748 Genomic DNA. Translation: BAA05941.1.
CP000077 Genomic DNA. Translation: AAY79520.1.
PIRB54058.
RefSeqYP_254813.1. NC_007181.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING330779.Saci_0093.

Protocols and materials databases

DNASU3473869.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY79520; AAY79520; Saci_0093.
GeneID3473869.
KEGGsai:Saci_0093.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0472.
HOGENOMHOG000227679.
KOK01001.
OMAAINLMDG.
ProtClustDBCLSK802540.

Enzyme and pathway databases

BioCycSACI330779:GH9J-93-MONOMER.

Family and domain databases

InterProIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERPTHR22926. PTHR22926. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPT_SULAC
AccessionPrimary (citable) accession number: P39465
Secondary accession number(s): Q4JCF9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families