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Protein

Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Gene

gnpTA

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Enzyme regulationi

Inhibited by tunicamycin.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC:2.7.8.15)
Alternative name(s):
GlcNAc-1-P transferase
Short name:
G1PT
Short name:
GPT
N-acetylglucosamine-1-phosphate transferase
Gene namesi
Name:gnpTA
Ordered Locus Names:Saci_0093
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001018 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei228 – 248HelicalSequence analysisAdd BLAST21
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001087661 – 328Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferaseAdd BLAST328

Interactioni

Protein-protein interaction databases

STRINGi330779.Saci_0093.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG03199. Archaea.
COG0472. LUCA.
HOGENOMiHOG000227679.
KOiK01001.
OMAiYIVELMA.

Family and domain databases

InterProiIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39465-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVSLLGILL SVIVGFVVTL ISTKWVIGLC KKRGFTGKDI NKLTKDDVPV
60 70 80 90 100
LGGIGIVAGF VAGSFTFLLT SYNLSPGIEN VVVSILLSSL IIGFLGLLDD
110 120 130 140 150
IFNISQATRA FLPIFASIPL ILYSVGHTII SIPFLGKVNF GILFYIIILP
160 170 180 190 200
ATLTITANAF NMLEGLNGLG AGMGLIMALA LAYIGLKSGG TSFYAGIVSI
210 220 230 240 250
ILASVLFGFL IFNFYPAKTF PGNIGTYFIG SVIGSIGISG YMYTALFFLY
260 270 280 290 300
LPYVIEFVLK AKTRFKGVSF GKIDDQGYLH WDSKPNSLTH IVMRIGKFKE
310 320
YHIVLIIWGI EILFAILAVV FQTVTITI
Length:328
Mass (Da):35,472
Last modified:February 1, 1995 - v1
Checksum:i01798FA2BD3297D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D28748 Genomic DNA. Translation: BAA05941.1.
CP000077 Genomic DNA. Translation: AAY79520.1.
PIRiB54058.
RefSeqiWP_011277021.1. NC_007181.1.

Genome annotation databases

EnsemblBacteriaiAAY79520; AAY79520; Saci_0093.
GeneIDi3473869.
KEGGisai:Saci_0093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D28748 Genomic DNA. Translation: BAA05941.1.
CP000077 Genomic DNA. Translation: AAY79520.1.
PIRiB54058.
RefSeqiWP_011277021.1. NC_007181.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi330779.Saci_0093.

Protocols and materials databases

DNASUi3473869.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY79520; AAY79520; Saci_0093.
GeneIDi3473869.
KEGGisai:Saci_0093.

Phylogenomic databases

eggNOGiarCOG03199. Archaea.
COG0472. LUCA.
HOGENOMiHOG000227679.
KOiK01001.
OMAiYIVELMA.

Family and domain databases

InterProiIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGPT_SULAC
AccessioniPrimary (citable) accession number: P39465
Secondary accession number(s): Q4JCF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.