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P39465

- GPT_SULAC

UniProt

P39465 - GPT_SULAC

Protein

Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Gene

gnpTA

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

    Enzyme regulationi

    Inhibited by tunicamycin.By similarity

    GO - Molecular functioni

    1. phospho-N-acetylmuramoyl-pentapeptide-transferase activity Source: InterPro
    2. transferase activity, transferring glycosyl groups Source: UniProtKB-KW
    3. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciSACI330779:GH9J-93-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC:2.7.8.15)
    Alternative name(s):
    GlcNAc-1-P transferase
    Short name:
    G1PT
    Short name:
    GPT
    N-acetylglucosamine-1-phosphate transferase
    Gene namesi
    Name:gnpTA
    Ordered Locus Names:Saci_0093
    OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
    Taxonomic identifieri330779 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
    ProteomesiUP000001018: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 328328Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferasePRO_0000108766Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi330779.Saci_0093.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1 – 2121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei48 – 6821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei78 – 9821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei107 – 12721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei129 – 14921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei166 – 18621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei192 – 21221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei228 – 24821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei301 – 32121HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 4 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0472.
    HOGENOMiHOG000227679.
    KOiK01001.
    OMAiRVGWADQ.

    Family and domain databases

    InterProiIPR000715. Glycosyl_transferase_4.
    [Graphical view]
    PANTHERiPTHR22926. PTHR22926. 1 hit.
    PfamiPF00953. Glycos_transf_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P39465-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLVSLLGILL SVIVGFVVTL ISTKWVIGLC KKRGFTGKDI NKLTKDDVPV    50
    LGGIGIVAGF VAGSFTFLLT SYNLSPGIEN VVVSILLSSL IIGFLGLLDD 100
    IFNISQATRA FLPIFASIPL ILYSVGHTII SIPFLGKVNF GILFYIIILP 150
    ATLTITANAF NMLEGLNGLG AGMGLIMALA LAYIGLKSGG TSFYAGIVSI 200
    ILASVLFGFL IFNFYPAKTF PGNIGTYFIG SVIGSIGISG YMYTALFFLY 250
    LPYVIEFVLK AKTRFKGVSF GKIDDQGYLH WDSKPNSLTH IVMRIGKFKE 300
    YHIVLIIWGI EILFAILAVV FQTVTITI 328
    Length:328
    Mass (Da):35,472
    Last modified:February 1, 1995 - v1
    Checksum:i01798FA2BD3297D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D28748 Genomic DNA. Translation: BAA05941.1.
    CP000077 Genomic DNA. Translation: AAY79520.1.
    PIRiB54058.
    RefSeqiWP_011277021.1. NC_007181.1.
    YP_254813.1. NC_007181.1.

    Genome annotation databases

    EnsemblBacteriaiAAY79520; AAY79520; Saci_0093.
    GeneIDi3473869.
    KEGGisai:Saci_0093.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D28748 Genomic DNA. Translation: BAA05941.1 .
    CP000077 Genomic DNA. Translation: AAY79520.1 .
    PIRi B54058.
    RefSeqi WP_011277021.1. NC_007181.1.
    YP_254813.1. NC_007181.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 330779.Saci_0093.

    Protocols and materials databases

    DNASUi 3473869.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY79520 ; AAY79520 ; Saci_0093 .
    GeneIDi 3473869.
    KEGGi sai:Saci_0093.

    Phylogenomic databases

    eggNOGi COG0472.
    HOGENOMi HOG000227679.
    KOi K01001.
    OMAi RVGWADQ.

    Enzyme and pathway databases

    BioCyci SACI330779:GH9J-93-MONOMER.

    Family and domain databases

    InterProi IPR000715. Glycosyl_transferase_4.
    [Graphical view ]
    PANTHERi PTHR22926. PTHR22926. 1 hit.
    Pfami PF00953. Glycos_transf_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Archaebacterial ether-linked lipid biosynthetic gene. Expression cloning, sequencing, and characterization of geranylgeranyl-diphosphate synthase."
      Ohnuma S., Suzuki M., Nishino T.
      J. Biol. Chem. 269:14792-14797(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.
    2. "The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota."
      Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.
      J. Bacteriol. 187:4992-4999(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.

    Entry informationi

    Entry nameiGPT_SULAC
    AccessioniPrimary (citable) accession number: P39465
    Secondary accession number(s): Q4JCF9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3