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Protein

Uncharacterized metal-dependent hydrolase YjjV

Gene

yjjV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

a divalent metal cation1 PublicationNote: Binds 2 divalent metal cations per subunit.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi9 – 91Divalent metal cation 11 Publication
Metal bindingi11 – 111Divalent metal cation 11 Publication
Metal bindingi97 – 971Divalent metal cation 11 Publication
Metal bindingi97 – 971Divalent metal cation 21 Publication
Metal bindingi133 – 1331Divalent metal cation 21 Publication
Metal bindingi157 – 1571Divalent metal cation 21 Publication
Metal bindingi207 – 2071Divalent metal cation 11 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7952-MONOMER.
ECOL316407:JW4341-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized metal-dependent hydrolase YjjVCurated (EC:3.1.-.-Curated)
Gene namesi
Name:yjjV
Ordered Locus Names:b4378, JW4341
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12598. yjjV.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Uncharacterized metal-dependent hydrolase YjjVPRO_0000201999Add
BLAST

Proteomic databases

PaxDbiP39408.
PRIDEiP39408.

Interactioni

Protein-protein interaction databases

BioGridi4261644. 70 interactions.
DIPiDIP-12661N.
IntActiP39408. 4 interactions.
MINTiMINT-1227009.
STRINGi511145.b4378.

Structurei

Secondary structure

1
259
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 84Combined sources
Turni15 – 195Combined sources
Helixi21 – 3010Combined sources
Beta strandi33 – 397Combined sources
Helixi43 – 453Combined sources
Helixi46 – 5510Combined sources
Beta strandi59 – 635Combined sources
Helixi67 – 726Combined sources
Helixi75 – 8713Combined sources
Beta strandi90 – 10112Combined sources
Helixi109 – 12517Combined sources
Beta strandi130 – 1367Combined sources
Helixi138 – 14811Combined sources
Beta strandi154 – 1563Combined sources
Helixi163 – 1719Combined sources
Beta strandi175 – 1784Combined sources
Helixi180 – 1834Combined sources
Turni185 – 1873Combined sources
Helixi190 – 1967Combined sources
Helixi199 – 2013Combined sources
Beta strandi202 – 2043Combined sources
Helixi223 – 2253Combined sources
Helixi226 – 23611Combined sources
Helixi241 – 25616Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZZMX-ray1.80A1-259[»]
ProteinModelPortaliP39408.
SMRiP39408. Positions 1-259.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP39408.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatD-type hydrolase family.Curated

Phylogenomic databases

eggNOGiENOG4105EYA. Bacteria.
COG0084. LUCA.
HOGENOMiHOG000201521.
InParanoidiP39408.
KOiK03424.
OMAiGAATWPQ.
OrthoDBiEOG66QM1C.
PhylomeDBiP39408.

Family and domain databases

InterProiIPR018228. DNase_TatD-rel_CS.
IPR032466. Metal_Hydrolase.
IPR001130. TatD_family.
[Graphical view]
PANTHERiPTHR10060. PTHR10060. 1 hit.
PfamiPF01026. TatD_DNase. 1 hit.
[Graphical view]
PIRSFiPIRSF005902. DNase_TatD. 1 hit.
SUPFAMiSSF51556. SSF51556. 1 hit.
PROSITEiPS01137. TATD_1. 1 hit.
PS01090. TATD_2. 1 hit.
PS01091. TATD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39408-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MICRFIDTHC HFDFPPFSGD EEASLQRAAQ AGVGKIIVPA TEAENFARVL
60 70 80 90 100
ALAENYQPLY AALGLHPGML EKHSDVSLEQ LQQALERRPA KVVAVGEIGL
110 120 130 140 150
DLFGDDPQFE RQQWLLDEQL KLAKRYDLPV ILHSRRTHDK LAMHLKRHDL
160 170 180 190 200
PRTGVVHGFS GSLQQAERFV QLGYKIGVGG TITYPRASKT RDVIAKLPLA
210 220 230 240 250
SLLLETDAPD MPLNGFQGQP NRPEQAARVF AVLCELRREP ADEIAQALLN

NTYTLFNVP
Length:259
Mass (Da):28,909
Last modified:November 1, 1995 - v2
Checksum:i9BFB42FAA760DC67
GO

Sequence cautioni

The sequence AAA97274.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97274.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77331.2.
AP009048 Genomic DNA. Translation: BAE78367.1.
PIRiS56602.
RefSeqiWP_000563040.1. NZ_LN832404.1.
YP_026291.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC77331; AAC77331; b4378.
BAE78367; BAE78367; BAE78367.
GeneIDi2847741.
KEGGiecj:JW4341.
eco:b4378.
PATRICi32124368. VBIEscCol129921_4524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97274.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77331.2.
AP009048 Genomic DNA. Translation: BAE78367.1.
PIRiS56602.
RefSeqiWP_000563040.1. NZ_LN832404.1.
YP_026291.2. NC_000913.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZZMX-ray1.80A1-259[»]
ProteinModelPortaliP39408.
SMRiP39408. Positions 1-259.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261644. 70 interactions.
DIPiDIP-12661N.
IntActiP39408. 4 interactions.
MINTiMINT-1227009.
STRINGi511145.b4378.

Proteomic databases

PaxDbiP39408.
PRIDEiP39408.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77331; AAC77331; b4378.
BAE78367; BAE78367; BAE78367.
GeneIDi2847741.
KEGGiecj:JW4341.
eco:b4378.
PATRICi32124368. VBIEscCol129921_4524.

Organism-specific databases

EchoBASEiEB2483.
EcoGeneiEG12598. yjjV.

Phylogenomic databases

eggNOGiENOG4105EYA. Bacteria.
COG0084. LUCA.
HOGENOMiHOG000201521.
InParanoidiP39408.
KOiK03424.
OMAiGAATWPQ.
OrthoDBiEOG66QM1C.
PhylomeDBiP39408.

Enzyme and pathway databases

BioCyciEcoCyc:G7952-MONOMER.
ECOL316407:JW4341-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP39408.
PROiP39408.

Family and domain databases

InterProiIPR018228. DNase_TatD-rel_CS.
IPR032466. Metal_Hydrolase.
IPR001130. TatD_family.
[Graphical view]
PANTHERiPTHR10060. PTHR10060. 1 hit.
PfamiPF01026. TatD_DNase. 1 hit.
[Graphical view]
PIRSFiPIRSF005902. DNase_TatD. 1 hit.
SUPFAMiSSF51556. SSF51556. 1 hit.
PROSITEiPS01137. TATD_1. 1 hit.
PS01090. TATD_2. 1 hit.
PS01091. TATD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
    Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
    Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Crystal structure of yjjV, tatD homolog from Escherichia coli K12, at 1.8 A resolution."
    New York structural genomics research consortium (NYSGRC)
    Submitted (FEB-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) IN COMPLEX WITH ZINC IONS.

Entry informationi

Entry nameiYJJV_ECOLI
AccessioniPrimary (citable) accession number: P39408
Secondary accession number(s): P78143, Q2M5T9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1995
Last modified: April 13, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.