Reviewed, UniProtKB/Swiss-Prot P39404 (BGLJ_ECOLI)

Names and originHide

Protein names

Recommended name:
Transcriptional activator protein BglJ

Gene names

Name:	bglJ
Synonyms:	yjjR
Ordered Locus Names:	b4366, JW5955

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributesHide

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)Hide

Function	Mutation in bglJ activates the bgl operon.
Sequence similarities	Contains 1 HTH luxR-type DNA-binding domain.
Sequence caution	The sequence AAA97265.1 differs from that shown. Reason: Erroneous initiation. The sequence AAB49332.1 differs from that shown. Reason: Erroneous initiation. The sequence BAE78356.1 differs from that shown. Reason: Erroneous initiation.

OntologiesHide

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	positive regulation of gene-specific transcription Inferred from direct assay. Source: UniProtKB transcription Inferred from mutant phenotype. Source: UniProtKB two-component signal transduction system (phosphorelay) Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription activator activity Inferred from direct assay. Source: UniProtKB transcription factor activity Inferred from direct assay. Source: UniProtKB two-component response regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)Hide

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 175	175	Transcriptional activator protein BglJ		PRO_0000184140
Regions
	Domain	96 – 161	66	HTH luxR-type
	DNA binding	120 – 139	20	H-T-H motif Potential

SequencesHide

	Sequence		Length	Mass (Da)
	P39404-1 [UniParc]. Last modified December 15, 1998. Version 2. Checksum: 4B84C8A2769DC2E2	FASTA	175	19,849
	10 20 30 40 50 60 MSRISFAAVI FSFSAMRSER REGLSCLTEL AIKFPRTRRL VIADDDIEAR LIGSLSPSPL 70 80 90 100 110 120 DGVLSKASTL EIFHQELFLS LNGVRQATDR LNNQWYINQS RTLSPTEREI LRFMSRGYSM 130 140 150 160 170 TQIAEQLKRN IKTIRAHKFN VMSKLGVSSD AGLLEAADIL LCMRHCETSN VLHPY

ReferencesHide

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12." Giel M., Desnoyer M., Lopilato J. Genetics 143:627-635(1996) [PubMed: 8725214] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: MRI804.
[2]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed: 7610040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-referencesHide

Sequence databases
EMBL GenBank DDBJ	U35834 Genomic DNA. Translation: AAB49332.1. Different initiation. U14003 Genomic DNA. Translation: AAA97265.1. Different initiation. U00096 Genomic DNA. Translation: AAC77322.3. AP009048 Genomic DNA. Translation: BAE78356.1. Different initiation.
RefSeq	AP_004855.1. NP_418786.3.
3D structure databases
SMR	P39404. Positions 6-157.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-9217N.
MINT	MINT-1268192.
STRING	P39404.
Genome annotation databases
EnsemblBacteria	EBESCT00000002557; EBESCP00000002557; EBESCG00000002087. EBESCT00000014946; EBESCP00000014237; EBESCG00000014006.
GeneID	948889.
GenomeReviews	Gene locus JW5955 in contig AP009048_GR. Gene locus b4366 in contig U00096_GR.
KEGG	ecj:JW5955. eco:b4366.
Organism-specific databases
EchoBASE	EB2479.
EcoGene	EG12594. bglJ.
CMR	Search...
Phylogenomic databases
eggNOG	COG2197.
HOGENOM	HBG416721.
OMA	ANNESEM.
ProtClustDB	PRK11475.
Enzyme and pathway databases
BioCyc	EcoCyc:G7948-MONOMER. ECOL168927:B4366-MONOMER.
Gene expression databases
Genevestigator	P39404.
Family and domain databases
InterPro	IPR016032. Sig_transdc_resp-reg_C-effctor. IPR000792. Tscrpt_reg_LuxR_C. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF00196. GerE. 1 hit. [Graphical view]
PRINTS	PR00038. HTHLUXR.
SMART	SM00421. HTH_LUXR. 1 hit. [Graphical view]
SUPFAM	SSF46894. Bipartite_resp_reg_C-effector. 1 hit.
PROSITE	PS00622. HTH_LUXR_1. False negative. PS50043. HTH_LUXR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry informationHide

Entry name

BGLJ_ECOLI

Accession

Primary (citable) accession number: P39404
Secondary accession number(s): Q2M5V0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	December 15, 1998
Last modified:	July 13, 2010
This is version 79 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)