P39361 (SGCR_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative sgc region transcriptional regulator

Gene names

Name:	sgcR
Synonyms:	yjhJ
Ordered Locus Names:	b4300, JW4262

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Putative transcriptional regulator for the sgcREAQCX region.
Sequence similarities	Contains 1 HTH deoR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 260	260	Putative sgc region transcriptional regulator		PRO_0000050267
Regions
	Domain	5 – 61	57	HTH deoR-type
	DNA binding	22 – 41	20	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	P39361 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 3DF397A5EFFCD5F9	FASTA	260	29,268
	10 20 30 40 50 60 MSQQRPDRIK QMLHYLWQHR HLSTQQAMEL FGYAEATVRR DFQYIVNQYP GMIRGHGCLD 70 80 90 100 110 120 FDDSTDDKEY VFDVKRTLQS VAKREIAALA RTMIKDGDCF FLDSGSTCLE LAKCLADARV 130 140 150 160 170 180 KVICNDIKIA NELGCFPHVE SYIIGGLIRP GYFSVGESLA LEMINAFSVE RAFISCDALS 190 200 210 220 230 240 LETGITNATM FEVGVKTRII QRSREVILMA DHSKFDAVEP HAVATLSCIK TIISDSGLPE 250 260 TIAQRYQRAG CQLFLPHSIK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Novel phosphotransferases system genes revealed by bacterial genome analysis: operons encoding homologues of sugar-specific permease domains of the phosphotransferase system and pentose catabolic enzymes." Reizer J., Charbit A., Reizer A., Saier M.H. Jr. Genome Sci. Technol. 1:53-75(1996) Cited for: DISCUSSION OF SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U14003 Genomic DNA. Translation: AAA97196.1. U00096 Genomic DNA. Translation: AAC77256.1. AP009048 Genomic DNA. Translation: BAE78291.1.
PIR	S56525.
RefSeq	NP_418720.1. NC_000913.2. YP_492432.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P39361.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-10880N.
IntAct	P39361. 1 interaction.
STRING	511145.b4300.
Proteomic databases
PRIDE	P39361.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC77256; AAC77256; b4300. BAE78291; BAE78291; BAE78291.
GeneID	12931983. 946830.
KEGG	ecj:Y75_p4184. eco:b4300.
PATRIC	32124186. VBIEscCol129921_4436.
Organism-specific databases
EchoBASE	EB2440.
EcoGene	EG12552. sgcR.
Phylogenomic databases
eggNOG	COG1349.
HOGENOM	HOG000028629.
OMA	LIMPDPS.
ProtClustDB	CLSK891828.
Enzyme and pathway databases
BioCyc	EcoCyc:G7913-MONOMER. ECOL316407:JW4262-MONOMER.
Gene expression databases
Genevestigator	P39361.
Family and domain databases
InterPro	IPR014036. DeoR_C. IPR001034. HTH_DeoR_N. IPR018356. Tscrpt_reg_HTH_DeoR_CS. [Graphical view]
Pfam	PF00455. DeoRC. 1 hit. PF08220. HTH_DeoR. 1 hit. [Graphical view]
SMART	SM00420. HTH_DEOR. 1 hit. [Graphical view]
PROSITE	PS00894. HTH_DEOR_1. 1 hit. PS51000. HTH_DEOR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SGCR_ECOLI

Accession

Primary (citable) accession number: P39361
Secondary accession number(s): Q2M615

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program