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Protein

Uncharacterized oxidoreductase YjhC

Gene

yjhC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:G7901-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YjhC (EC:1.-.-.-)
Gene namesi
Name:yjhC
Ordered Locus Names:b4280, JW5769
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12545 yjhC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000917811 – 372Uncharacterized oxidoreductase YjhCAdd BLAST372

Proteomic databases

PaxDbiP39353
PRIDEiP39353

Expressioni

Inductioni

Negatively regulated by the transcriptional repressor NanR. Induced by N-acetylneuraminate, via inactivation of NanR.1 Publication

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
metNP307503EBI-542024,EBI-541886

Protein-protein interaction databases

BioGridi4261650, 8 interactors
DIPiDIP-12617N
IntActiP39353, 2 interactors
STRINGi316385.ECDH10B_4475

Structurei

3D structure databases

ProteinModelPortaliP39353
SMRiP39353
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.Curated

Phylogenomic databases

eggNOGiENOG4107RJ5 Bacteria
COG0673 LUCA
HOGENOMiHOG000244297
InParanoidiP39353
OMAiGGMLLDW
PhylomeDBiP39353

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR000683 Oxidoreductase_N
IPR004104 OxRdtase_C
PfamiView protein in Pfam
PF01408 GFO_IDH_MocA, 1 hit
PF02894 GFO_IDH_MocA_C, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

P39353-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINYGVVGVG YFGAELARFM NMHDNAKITC VYDPENGENI ARELQCINMS
60 70 80 90 100
SLDALVSSKL VDCVIVATPN YLHKEPVIKA AKNKKHVFCE KPIALSYEDC
110 120 130 140 150
VDMVKACKEA GVTFMAGHIM NFFNGVQYAR KLIKEGVIGE ILSCHTKRNG
160 170 180 190 200
WENKQERLSW KKMKEQSGGH LYHHIHELDC VQHLLGEIPE TVTMIGGNLA
210 220 230 240 250
HSGPGFGNED DMLFMTLEFP SGKLATLEWG SAFNWPEHYV IINGTKGSIK
260 270 280 290 300
IDMQETAGSL RIGGQTKHFL VHETQEEDDD RRKGNMTSEM DGAIAYGHPG
310 320 330 340 350
KKTPLWLASL IRKETLFLHN ILCGAKPEED YIDLLNGEAA MSAIATADAA
360 370
TLSRSQDRKV KISEIIKHTS VM
Length:372
Mass (Da):41,384
Last modified:December 15, 1998 - v2
Checksum:i34B2E535EADC2ABE
GO

Sequence cautioni

The sequence AAA97176 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97176.1 Different initiation.
U00096 Genomic DNA Translation: AAC77236.2
AP009048 Genomic DNA Translation: BAE78274.1
PIRiS56505
RefSeqiNP_418700.2, NC_000913.3
WP_000611568.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77236; AAC77236; b4280
BAE78274; BAE78274; BAE78274
GeneIDi948808
KEGGiecj:JW5769
eco:b4280
PATRICifig|1411691.4.peg.2423

Similar proteinsi

Entry informationi

Entry nameiYJHC_ECOLI
AccessioniPrimary (citable) accession number: P39353
Secondary accession number(s): Q2M632
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: December 15, 1998
Last modified: March 28, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health