P39353 (YJHC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized oxidoreductase YjhC
EC=1.-.-.-

Gene names

Name:	yjhC
Ordered Locus Names:	b4280, JW5769

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	372 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the Gfo/Idh/MocA family.
Sequence caution	The sequence AAA97176.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to DNA damage stimulus Inferred from expression pattern PubMed 11967071. Source: EcoliWiki
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 372	372	Uncharacterized oxidoreductase YjhC		PRO_0000091781

Sequences

	Sequence		Length	Mass (Da)
	P39353 [UniParc]. Last modified December 15, 1998. Version 2. Checksum: 34B2E535EADC2ABE	FASTA	372	41,384
	10 20 30 40 50 60 MINYGVVGVG YFGAELARFM NMHDNAKITC VYDPENGENI ARELQCINMS SLDALVSSKL 70 80 90 100 110 120 VDCVIVATPN YLHKEPVIKA AKNKKHVFCE KPIALSYEDC VDMVKACKEA GVTFMAGHIM 130 140 150 160 170 180 NFFNGVQYAR KLIKEGVIGE ILSCHTKRNG WENKQERLSW KKMKEQSGGH LYHHIHELDC 190 200 210 220 230 240 VQHLLGEIPE TVTMIGGNLA HSGPGFGNED DMLFMTLEFP SGKLATLEWG SAFNWPEHYV 250 260 270 280 290 300 IINGTKGSIK IDMQETAGSL RIGGQTKHFL VHETQEEDDD RRKGNMTSEM DGAIAYGHPG 310 320 330 340 350 360 KKTPLWLASL IRKETLFLHN ILCGAKPEED YIDLLNGEAA MSAIATADAA TLSRSQDRKV 370 KISEIIKHTS VM

References

[1]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U14003 Genomic DNA. Translation: AAA97176.1. Different initiation. U00096 Genomic DNA. Translation: AAC77236.2. AP009048 Genomic DNA. Translation: BAE78274.1.
PIR	S56505.
RefSeq	NP_418700.2. NC_000913.2. YP_492415.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P39353.
SMR	P39353. Positions 2-366.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12617N.
IntAct	P39353. 2 interactions.
MINT	MINT-1283412.
STRING	511145.b4280.
Proteomic databases
PaxDb	P39353.
PRIDE	P39353.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC77236; AAC77236; b4280. BAE78274; BAE78274; BAE78274.
GeneID	12932656. 948808.
KEGG	ecj:Y75_p4161. eco:b4280.
PATRIC	32124133. VBIEscCol129921_4410.
Organism-specific databases
EchoBASE	EB2433.
EcoGene	EG12545. yjhC.
Phylogenomic databases
eggNOG	COG0673.
HOGENOM	HOG000244297.
OMA	HEGENFG.
ProtClustDB	CLSK870604.
Enzyme and pathway databases
BioCyc	EcoCyc:G7901-MONOMER. ECOL316407:JW5769-MONOMER.
Gene expression databases
Genevestigator	P39353.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR004104. OxRdtase_C. [Graphical view]
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF02894. GFO_IDH_MocA_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YJHC_ECOLI

Accession

Primary (citable) accession number: P39353
Secondary accession number(s): Q2M632

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	December 15, 1998
Last modified:	May 1, 2013
This is version 96 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program