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Protein

Putative protein IntB

Gene

intB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Additional homology to the integrase family exists upstream of the current start codon.Curated
Could be the product of a pseudogene.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei353O-(3'-phospho-DNA)-tyrosine intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA integration, DNA recombination, Viral genome integration, Virus entry into host cell

Enzyme and pathway databases

BioCyciEcoCyc:EG12364-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein IntBCurated
Alternative name(s):
Int(P4)
Putative prophage P4 integrase
Gene namesi
Name:intB
Ordered Locus Names:b4271, JW4227
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12364 intB

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001975121 – 396Putative protein IntBAdd BLAST396

Proteomic databases

PRIDEiP39347

Interactioni

Protein-protein interaction databases

BioGridi4262732, 18 interactors
DIPiDIP-10035N
IntActiP39347, 15 interactors
STRINGi316385.ECDH10B_4464

Structurei

3D structure databases

ProteinModelPortaliP39347
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family.Curated

Phylogenomic databases

eggNOGiCOG0582 LUCA
HOGENOMiHOG000263105
InParanoidiP39347
OMAiAVARDWH
PhylomeDBiP39347

Family and domain databases

Gene3Di1.10.150.130, 1 hit
1.10.443.10, 1 hit
3.30.160.390, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR002104 Integrase_catalytic
IPR038488 Integrase_DNA-bd_sf
IPR025166 Integrase_DNA_bind_dom
IPR010998 Integrase_recombinase_N
PfamiView protein in Pfam
PF13356 Arm-DNA-bind_3, 1 hit
PF00589 Phage_integrase, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit

Sequencei

Sequence statusi: Complete.

P39347-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLLVHPNGS KYWRLQYRYE GKQKMLALGV YPEITLADAR VRRDEARKLL
60 70 80 90 100
ANGVDPGDKK KNDKVEQSKA RTFKEVAIEW HGTNKKWSED HAHRVLKSLE
110 120 130 140 150
DNLFAALGER NIAELKTRDL LAPIKAVEMS GRLEVAARLQ QRTTAIMRYA
160 170 180 190 200
VQSGLIDYNP AQEMAGAVAS CNRQHRPALE LKRIPELLTK IDSYTGRPLT
210 220 230 240 250
RWAIELTLLI FIRSSELRFA RWSEIDFEAS IWTIPPEREP IPGVKHSHRG
260 270 280 290 300
SKMRTTHLVP LSTQALAILK QIKQFYGAHD LIFIGDHDSH KPMSENTVNS
310 320 330 340 350
ALRVMGYDTK VEVCGHGFRT MACSSLVESG LWSRDAVERQ MSHMARNSVR
360 370 380 390
AAYIHKAEHL EERRLMLQWW ADFLDVNRER FISPFEYAKI NNPLKQ
Length:396
Mass (Da):45,582
Last modified:February 1, 1995 - v1
Checksum:iDE3762C1EFC8BFCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97167.1
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAE78267.1
M96355 Genomic DNA No translation available.
PIRiS56496
RefSeqiWP_000550469.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiBAE78267; BAE78267; BAE78267
KEGGiecj:JW4227
PATRICifig|83333.103.peg.579

Similar proteinsi

Entry informationi

Entry nameiINTB_ECOLI
AccessioniPrimary (citable) accession number: P39347
Secondary accession number(s): Q2M639
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health