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Protein

HTH-type transcriptional regulator IdnR

Gene

idnR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi8 – 2720H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Gluconate utilization, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7891-MONOMER.
ECOL316407:JW4221-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator IdnR
Alternative name(s):
L-idonate regulatory protein
Gene namesi
Name:idnR
Synonyms:yjgS
Ordered Locus Names:b4264, JW4221
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12538. idnR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332HTH-type transcriptional regulator IdnRPRO_0000107960Add
BLAST

Proteomic databases

PaxDbiP39343.

Interactioni

Protein-protein interaction databases

BioGridi4262722. 6 interactions.
IntActiP39343. 3 interactions.
STRINGi511145.b4264.

Structurei

3D structure databases

ProteinModelPortaliP39343.
SMRiP39343. Positions 6-332.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 6055HTH lacI-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lacI-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105K2J. Bacteria.
ENOG410ZETB. LUCA.
HOGENOMiHOG000220181.
InParanoidiP39343.
KOiK06146.
OMAiIVCANDL.
PhylomeDBiP39343.

Family and domain databases

CDDicd01392. HTH_LacI. 1 hit.
Gene3Di1.10.260.40. 1 hit.
InterProiIPR000843. HTH_LacI.
IPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00356. LacI. 1 hit.
[Graphical view]
SMARTiSM00354. HTH_LACI. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEiPS00356. HTH_LACI_1. 1 hit.
PS50932. HTH_LACI_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39343-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNHRISLQD IATLAGVTKM TVSRYIRSPK KVAKETGERI AKIMEEINYI
60 70 80 90 100
PNRAPGMLLN AQSYTLGILI PSFQNQLFAD ILAGIESVTS EHNYQTLIAN
110 120 130 140 150
YNYDRDSEEE SVINLLSYNI DGIILSEKYH TIRTVKFLRS ATIPVVELMD
160 170 180 190 200
VQGERLDMEV GFDNRQAAFD MVCTMLEKRV RHKILYLGSK DDTRDEQRYQ
210 220 230 240 250
GYCDAMMLHN LSPLRMNPRA ISSIHLGMQL MRDALSANPD LDGVFCTNDD
260 270 280 290 300
IAMGALLLCR ERNLAVPEQI SIAGFHGLEI GRQMIPSLAS VITPRFDIGR
310 320 330
MAAQMLLSKI KNNDHNHNTV DLGYQIYHGN TL
Length:332
Mass (Da):37,567
Last modified:February 1, 1995 - v1
Checksum:i9F18972E86DAFBF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97161.1.
U00096 Genomic DNA. Translation: AAC77221.1.
AP009048 Genomic DNA. Translation: BAE78261.1.
PIRiS56490.
RefSeqiNP_418685.1. NC_000913.3.
WP_001309159.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77221; AAC77221; b4264.
BAE78261; BAE78261; BAE78261.
GeneIDi949058.
KEGGiecj:JW4221.
eco:b4264.
PATRICi32124101. VBIEscCol129921_4395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97161.1.
U00096 Genomic DNA. Translation: AAC77221.1.
AP009048 Genomic DNA. Translation: BAE78261.1.
PIRiS56490.
RefSeqiNP_418685.1. NC_000913.3.
WP_001309159.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39343.
SMRiP39343. Positions 6-332.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262722. 6 interactions.
IntActiP39343. 3 interactions.
STRINGi511145.b4264.

Proteomic databases

PaxDbiP39343.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77221; AAC77221; b4264.
BAE78261; BAE78261; BAE78261.
GeneIDi949058.
KEGGiecj:JW4221.
eco:b4264.
PATRICi32124101. VBIEscCol129921_4395.

Organism-specific databases

EchoBASEiEB2427.
EcoGeneiEG12538. idnR.

Phylogenomic databases

eggNOGiENOG4105K2J. Bacteria.
ENOG410ZETB. LUCA.
HOGENOMiHOG000220181.
InParanoidiP39343.
KOiK06146.
OMAiIVCANDL.
PhylomeDBiP39343.

Enzyme and pathway databases

BioCyciEcoCyc:G7891-MONOMER.
ECOL316407:JW4221-MONOMER.

Miscellaneous databases

PROiP39343.

Family and domain databases

CDDicd01392. HTH_LacI. 1 hit.
Gene3Di1.10.260.40. 1 hit.
InterProiIPR000843. HTH_LacI.
IPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00356. LacI. 1 hit.
[Graphical view]
SMARTiSM00354. HTH_LACI. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEiPS00356. HTH_LACI_1. 1 hit.
PS50932. HTH_LACI_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIDNR_ECOLI
AccessioniPrimary (citable) accession number: P39343
Secondary accession number(s): Q2M645
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.