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Protein

HTH-type transcriptional repressor BdcR

Gene

bdcR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Negatively regulates expression of bdcA.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi38 – 57H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G7882-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional repressor BdcR
Gene namesi
Name:bdcR
Synonyms:yjgJ
Ordered Locus Names:b4251, JW4208
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12529 bdcR

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000706471 – 197HTH-type transcriptional repressor BdcRAdd BLAST197

Proteomic databases

PaxDbiP39334
PRIDEiP39334

Interactioni

Protein-protein interaction databases

BioGridi4259559, 174 interactors
IntActiP39334, 1 interactor
STRINGi316385.ECDH10B_4444

Structurei

3D structure databases

ProteinModelPortaliP39334
SMRiP39334
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 75HTH tetR-typePROSITE-ProRule annotationAdd BLAST61

Phylogenomic databases

eggNOGiENOG4108XFH Bacteria
ENOG4111MNX LUCA
HOGENOMiHOG000161265
InParanoidiP39334
KOiK19335
OMAiHARGYDA
PhylomeDBiP39334

Family and domain databases

InterProiView protein in InterPro
IPR023772 DNA-bd_HTH_TetR-type_CS
IPR009057 Homeobox-like_sf
IPR001647 HTH_TetR
IPR036271 Tet_transcr_reg_TetR-rel_C_sf
PfamiView protein in Pfam
PF00440 TetR_N, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF48498 SSF48498, 1 hit
PROSITEiView protein in PROSITE
PS01081 HTH_TETR_1, 1 hit
PS50977 HTH_TETR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P39334-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTKKQSRVP GRPRRFAPEQ AISAAKVLFH QKGFDAVSVA EVTDYLGINP
60 70 80 90 100
PSLYAAFGSK AGLFSRVLNE YVGTEAIPLA DILRDDRPVG ECLVEVLKEA
110 120 130 140 150
ARRYSQNGGC AGCMVLEGIH SHDPQARDIA VQYYHAAETT IYDYIARRHP
160 170 180 190
QRAQCVTDFM STVMSGLSAK AREGHSIEQL CATAAMAGEA IKTILEE
Length:197
Mass (Da):21,502
Last modified:July 15, 1998 - v2
Checksum:iC1E81B87A27435BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97147.1 Frameshift.
U00096 Genomic DNA Translation: AAC77208.2
AP009048 Genomic DNA Translation: BAE78248.1
PIRiS56476
RefSeqiNP_418672.4, NC_000913.3
WP_000256658.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77208; AAC77208; b4251
BAE78248; BAE78248; BAE78248
GeneIDi948775
KEGGiecj:JW4208
eco:b4251
PATRICifig|1411691.4.peg.2453

Entry informationi

Entry nameiBDCR_ECOLI
AccessioniPrimary (citable) accession number: P39334
Secondary accession number(s): P76809, Q2M658
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: July 15, 1998
Last modified: March 28, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health