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Protein

Inner membrane ABC transporter permease protein YtfT

Gene

ytfT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

  • galactose uniporter activity Source: EcoCyc

GO - Biological processi

  • galactose transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YTFT-MONOMER.
ECOL316407:JW5753-MONOMER.
MetaCyc:YTFT-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.25. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YtfT
Gene namesi
Name:ytfT
Ordered Locus Names:b4230, JW5753
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12520. ytfT.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525CytoplasmicSequence analysisAdd
BLAST
Transmembranei26 – 4621HelicalSequence analysisAdd
BLAST
Topological domaini47 – 6519PeriplasmicSequence analysisAdd
BLAST
Transmembranei66 – 8621HelicalSequence analysisAdd
BLAST
Transmembranei87 – 10721HelicalSequence analysisAdd
BLAST
Topological domaini108 – 1081PeriplasmicSequence analysis
Transmembranei109 – 12921HelicalSequence analysisAdd
BLAST
Topological domaini130 – 1367CytoplasmicSequence analysis
Transmembranei137 – 15721HelicalSequence analysisAdd
BLAST
Topological domaini158 – 17417PeriplasmicSequence analysisAdd
BLAST
Transmembranei175 – 19521HelicalSequence analysisAdd
BLAST
Topological domaini196 – 22328CytoplasmicSequence analysisAdd
BLAST
Transmembranei224 – 24421HelicalSequence analysisAdd
BLAST
Topological domaini245 – 25511PeriplasmicSequence analysisAdd
BLAST
Transmembranei256 – 27621HelicalSequence analysisAdd
BLAST
Topological domaini277 – 2815CytoplasmicSequence analysis
Transmembranei282 – 30221HelicalSequence analysisAdd
BLAST
Transmembranei303 – 32321HelicalSequence analysisAdd
BLAST
Topological domaini324 – 34118CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 341341Inner membrane ABC transporter permease protein YtfTPRO_0000060265Add
BLAST

Proteomic databases

PaxDbiP39328.
PRIDEiP39328.

Interactioni

Protein-protein interaction databases

BioGridi4259314. 8 interactions.
DIPiDIP-12946N.
IntActiP39328. 1 interaction.
MINTiMINT-1249310.
STRINGi511145.b4230.

Structurei

3D structure databases

ProteinModelPortaliP39328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107R9N. Bacteria.
ENOG410XPE9. LUCA.
HOGENOMiHOG000212234.
InParanoidiP39328.
KOiK02057.
OMAiFFQIVVQ.
PhylomeDBiP39328.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMPQSLPDTT TPKRRFRWPT GMPQLVALLL VLLVDSLVAP HFWQVVLQDG
60 70 80 90 100
RLFGSPIDIL NRAAPVALLA IGMTLVIATG GIDLSVGAVM AIAGATTAAM
110 120 130 140 150
TVAGFSLPIV LLSALGTGIL AGLWNGILVA ILKIQPFVAT LILMVAGRGV
160 170 180 190 200
AQLITAGQIV TFNSPDLSWF GSGSLLFLPT PVIIAVLTLI LFWLLTRKTA
210 220 230 240 250
LGMFIEAVGI NIRAAKNAGV NTRIIVMLTY VLSGLCAAIA GIIVAADIRG
260 270 280 290 300
ADANNAGLWL ELDAILAVVI GGGSLMGGRF NLLLSVVGAL IIQGMNTGIL
310 320 330 340
LSGFPPEMNQ VVKAVVVLCV LIVQSQRFIS LIKGVRSRDK T
Length:341
Mass (Da):35,659
Last modified:February 1, 1995 - v1
Checksum:iF005F90E580E89E5
GO

Sequence cautioni

The sequence BAE78230 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97127.1.
U00096 Genomic DNA. Translation: AAC77187.3.
AP009048 Genomic DNA. Translation: BAE78230.1. Different initiation.
PIRiS56456.
RefSeqiNP_418651.3. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC77187; AAC77187; b4230.
BAE78230; BAE78230; BAE78230.
GeneIDi948743.
KEGGiecj:JW5753.
eco:b4230.
PATRICi32124033. VBIEscCol129921_4361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97127.1.
U00096 Genomic DNA. Translation: AAC77187.3.
AP009048 Genomic DNA. Translation: BAE78230.1. Different initiation.
PIRiS56456.
RefSeqiNP_418651.3. NC_000913.3.

3D structure databases

ProteinModelPortaliP39328.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259314. 8 interactions.
DIPiDIP-12946N.
IntActiP39328. 1 interaction.
MINTiMINT-1249310.
STRINGi511145.b4230.

Protein family/group databases

TCDBi3.A.1.2.25. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP39328.
PRIDEiP39328.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77187; AAC77187; b4230.
BAE78230; BAE78230; BAE78230.
GeneIDi948743.
KEGGiecj:JW5753.
eco:b4230.
PATRICi32124033. VBIEscCol129921_4361.

Organism-specific databases

EchoBASEiEB2411.
EcoGeneiEG12520. ytfT.

Phylogenomic databases

eggNOGiENOG4107R9N. Bacteria.
ENOG410XPE9. LUCA.
HOGENOMiHOG000212234.
InParanoidiP39328.
KOiK02057.
OMAiFFQIVVQ.
PhylomeDBiP39328.

Enzyme and pathway databases

BioCyciEcoCyc:YTFT-MONOMER.
ECOL316407:JW5753-MONOMER.
MetaCyc:YTFT-MONOMER.

Miscellaneous databases

PROiP39328.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYTFT_ECOLI
AccessioniPrimary (citable) accession number: P39328
Secondary accession number(s): Q2M676
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 7, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.