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Protein

Inner membrane protein YtfF

Gene

ytfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7867-MONOMER.
ECOL316407:JW4168-MONOMER.

Protein family/group databases

TCDBi2.A.7.3.19. the drug/metabolite transporter (dmt) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YtfF
Gene namesi
Name:ytfF
Ordered Locus Names:b4210, JW4168
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12506. ytfF.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 4CytoplasmicSequence analysis4
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Topological domaini26 – 30PeriplasmicSequence analysis5
Transmembranei31 – 51HelicalSequence analysisAdd BLAST21
Topological domaini52 – 65CytoplasmicSequence analysisAdd BLAST14
Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Topological domaini87 – 92PeriplasmicSequence analysis6
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21
Topological domaini114 – 120CytoplasmicSequence analysis7
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Topological domaini142 – 154PeriplasmicSequence analysisAdd BLAST13
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Topological domaini176 – 194CytoplasmicSequence analysisAdd BLAST19
Transmembranei195 – 215HelicalSequence analysisAdd BLAST21
Topological domaini216 – 230PeriplasmicSequence analysisAdd BLAST15
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Topological domaini252 – 261CytoplasmicSequence analysis10
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Topological domaini283 – 285PeriplasmicSequence analysis3
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Topological domaini307 – 321CytoplasmicSequence analysisAdd BLAST15

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001698241 – 321Inner membrane protein YtfFAdd BLAST321

Proteomic databases

PaxDbiP39314.
PRIDEiP39314.

Interactioni

Protein-protein interaction databases

BioGridi4263163. 200 interactors.
STRINGi511145.b4210.

Structurei

3D structure databases

ProteinModelPortaliP39314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 141EamAAdd BLAST129

Sequence similaritiesi

Contains 1 EamA domain.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DXC. Bacteria.
ENOG410XR5C. LUCA.
HOGENOMiHOG000261708.
InParanoidiP39314.
PhylomeDBiP39314.

Family and domain databases

InterProiIPR000620. EamA_dom.
[Graphical view]
PfamiPF00892. EamA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39314-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISGVLYALL AGLMWGLIFV GPLIVPEYPA MLQSMGRYLA LGLIALPIAW
60 70 80 90 100
LGRVRLRQLA RRDWLTALML TMMGNLIYYF CLASAIQRTG APVSTMIIGT
110 120 130 140 150
LPVVIPVFAN LLYSQRDGKL AWGKLAPALI CIGIGLACVN IAELNHGLPD
160 170 180 190 200
FDWARYTSGI VLALVSVVCW AWYALRNARW LRENPDKHPM MWATAQALVT
210 220 230 240 250
LPVSLIGYLV ACYWLNTQTP DFSLPFGPRP LVFISLMVAI AVLCSWVGAL
260 270 280 290 300
CWNVASQLLP TVILGPLIVF ETLAGLLYTF LLRQQMPPLM TLSGIALLVI
310 320
GVVIAVRAKP EKPLTESVSE S
Length:321
Mass (Da):35,208
Last modified:November 24, 2009 - v2
Checksum:iD417608808BD0A3A
GO

Sequence cautioni

The sequence AAA97106 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE78211 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97106.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77167.2.
AP009048 Genomic DNA. Translation: BAE78211.1. Different initiation.
PIRiS56435.
RefSeqiNP_418631.2. NC_000913.3.
WP_001350569.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77167; AAC77167; b4210.
BAE78211; BAE78211; BAE78211.
GeneIDi948732.
KEGGiecj:JW4168.
eco:b4210.
PATRICi32123995. VBIEscCol129921_4342.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97106.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77167.2.
AP009048 Genomic DNA. Translation: BAE78211.1. Different initiation.
PIRiS56435.
RefSeqiNP_418631.2. NC_000913.3.
WP_001350569.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39314.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263163. 200 interactors.
STRINGi511145.b4210.

Protein family/group databases

TCDBi2.A.7.3.19. the drug/metabolite transporter (dmt) superfamily.

Proteomic databases

PaxDbiP39314.
PRIDEiP39314.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77167; AAC77167; b4210.
BAE78211; BAE78211; BAE78211.
GeneIDi948732.
KEGGiecj:JW4168.
eco:b4210.
PATRICi32123995. VBIEscCol129921_4342.

Organism-specific databases

EchoBASEiEB2399.
EcoGeneiEG12506. ytfF.

Phylogenomic databases

eggNOGiENOG4105DXC. Bacteria.
ENOG410XR5C. LUCA.
HOGENOMiHOG000261708.
InParanoidiP39314.
PhylomeDBiP39314.

Enzyme and pathway databases

BioCyciEcoCyc:G7867-MONOMER.
ECOL316407:JW4168-MONOMER.

Miscellaneous databases

PROiP39314.

Family and domain databases

InterProiIPR000620. EamA_dom.
[Graphical view]
PfamiPF00892. EamA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYTFF_ECOLI
AccessioniPrimary (citable) accession number: P39314
Secondary accession number(s): Q2M695
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 24, 2009
Last modified: November 2, 2016
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.