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Protein

Inner membrane transporter YjeM

Gene

yjeM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YJEM-MONOMER.
ECOL316407:JW5739-MONOMER.

Protein family/group databases

TCDBi2.A.3.7.5. the amino acid-polyamine-organocation (apc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transporter YjeM
Gene namesi
Name:yjeM
Ordered Locus Names:b4156, JW5739
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12475. yjeM.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 7CytoplasmicSequence analysis7
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Topological domaini29 – 37PeriplasmicSequence analysis9
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 82CytoplasmicSequence analysisAdd BLAST24
Transmembranei83 – 103HelicalSequence analysisAdd BLAST21
Topological domaini104 – 132PeriplasmicSequence analysisAdd BLAST29
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Topological domaini154 – 163CytoplasmicSequence analysis10
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Topological domaini185 – 209PeriplasmicSequence analysisAdd BLAST25
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Topological domaini231 – 243CytoplasmicSequence analysisAdd BLAST13
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Topological domaini265 – 319PeriplasmicSequence analysisAdd BLAST55
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21
Topological domaini341 – 369CytoplasmicSequence analysisAdd BLAST29
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Topological domaini391 – 394PeriplasmicSequence analysis4
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Topological domaini416 – 433CytoplasmicSequence analysisAdd BLAST18
Transmembranei434 – 454HelicalSequence analysisAdd BLAST21
Topological domaini455 – 462PeriplasmicSequence analysis8
Transmembranei463 – 483HelicalSequence analysisAdd BLAST21
Topological domaini484 – 500CytoplasmicSequence analysisAdd BLAST17

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002130461 – 500Inner membrane transporter YjeMAdd BLAST500

Proteomic databases

PaxDbiP39282.
PRIDEiP39282.

Interactioni

Protein-protein interaction databases

BioGridi4260878. 292 interactors.
STRINGi511145.b4156.

Structurei

3D structure databases

ProteinModelPortaliP39282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107SC7. Bacteria.
ENOG410XRYB. LUCA.
HOGENOMiHOG000127295.
InParanoidiP39282.
OMAiVVWMVST.
PhylomeDBiP39282.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.

Sequencei

Sequence statusi: Complete.

P39282-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPHTIKKMSL IGLILMIFTS VFGFANSPSA YYLMGYSAIP FYIFSALLFF
60 70 80 90 100
IPFALMMAEM GAAYRKEEGG IYSWMNNSVG PRFAFIGTFM WFSSYIIWMV
110 120 130 140 150
STSAKVWVPF STFLYGSDMT QHWRIAGLEP TQVVGLLAVA WMILVTVVAS
160 170 180 190 200
KGINKIARIT AVGGIAVMCL NLVLLLVSIT ILLLNGGHFA QDINFLASPN
210 220 230 240 250
PGYQSGLAML SFVVFAIFAY GGIEAVGGLV DKTENPEKNF AKGIVFAAIV
260 270 280 290 300
ISIGYSLAIF LWGVSTNWQQ VLSNGSVNLG NITYVLMKSL GMTLGNALHL
310 320 330 340 350
SPEASLSLGV WFARITGLSM FLAYTGAFFT LCYSPLKAII QGTPKALWPE
360 370 380 390 400
PMTRLNAMGM PSIAMWMQCG LVTVFILLVS FGGGTASAFF NKLTLMANVS
410 420 430 440 450
MTLPYLFLAL AFPFFKARQD LDRPFVIFKT HLSAMIATVV VVLVVTFANV
460 470 480 490 500
FTIIQPVVEA GDWDSTLWMI GGPVFFSLLA MAIYQNYCSR VAKNPQWAVE
Length:500
Mass (Da):54,725
Last modified:May 30, 2000 - v2
Checksum:i9B32EBFBD20A1AB4
GO

Sequence cautioni

The sequence AAA97055 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97055.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77116.2.
AP009048 Genomic DNA. Translation: BAE78160.1.
PIRiS56384.
RefSeqiNP_418580.2. NC_000913.3.
WP_001336293.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77116; AAC77116; b4156.
BAE78160; BAE78160; BAE78160.
GeneIDi948679.
KEGGiecj:JW5739.
eco:b4156.
PATRICi32123885. VBIEscCol129921_4290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97055.1. Different initiation.
U00096 Genomic DNA. Translation: AAC77116.2.
AP009048 Genomic DNA. Translation: BAE78160.1.
PIRiS56384.
RefSeqiNP_418580.2. NC_000913.3.
WP_001336293.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39282.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260878. 292 interactors.
STRINGi511145.b4156.

Protein family/group databases

TCDBi2.A.3.7.5. the amino acid-polyamine-organocation (apc) family.

Proteomic databases

PaxDbiP39282.
PRIDEiP39282.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77116; AAC77116; b4156.
BAE78160; BAE78160; BAE78160.
GeneIDi948679.
KEGGiecj:JW5739.
eco:b4156.
PATRICi32123885. VBIEscCol129921_4290.

Organism-specific databases

EchoBASEiEB2368.
EcoGeneiEG12475. yjeM.

Phylogenomic databases

eggNOGiENOG4107SC7. Bacteria.
ENOG410XRYB. LUCA.
HOGENOMiHOG000127295.
InParanoidiP39282.
OMAiVVWMVST.
PhylomeDBiP39282.

Enzyme and pathway databases

BioCyciEcoCyc:YJEM-MONOMER.
ECOL316407:JW5739-MONOMER.

Miscellaneous databases

PROiP39282.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYJEM_ECOLI
AccessioniPrimary (citable) accession number: P39282
Secondary accession number(s): Q2M6E6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: May 30, 2000
Last modified: November 2, 2016
This is version 125 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.