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Protein

Uncharacterized protein YfcC

Gene

yfcC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7190-MONOMER.
ECOL316407:JW2295-MONOMER.

Protein family/group databases

TCDBi2.A.118.1.8. the basic amino acid antiporter (arcd) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YfcC
Gene namesi
Name:yfcC
Ordered Locus Names:b2298, JW2295
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12607. yfcC.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei148 – 168HelicalSequence analysisAdd BLAST21
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Transmembranei287 – 307HelicalSequence analysisAdd BLAST21
Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Transmembranei398 – 418HelicalSequence analysisAdd BLAST21
Transmembranei419 – 439HelicalSequence analysisAdd BLAST21
Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001691911 – 506Uncharacterized protein YfcCAdd BLAST506

Proteomic databases

PaxDbiP39263.
PRIDEiP39263.

Interactioni

Protein-protein interaction databases

BioGridi4261493. 212 interactors.
DIPiDIP-11977N.
IntActiP39263. 2 interactors.
MINTiMINT-1315864.
STRINGi511145.b2298.

Structurei

3D structure databases

ProteinModelPortaliP39263.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To H.influenzae HI_0594.Curated
To B.subtilis YcgA.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CSX. Bacteria.
COG1288. LUCA.
HOGENOMiHOG000277481.
InParanoidiP39263.
OMAiTATILHW.
PhylomeDBiP39263.

Family and domain databases

InterProiIPR018385. C4_dicarb_anaerob_car-like.
[Graphical view]
PfamiPF03606. DcuC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39263-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAITESKPT RRWAMPDTLV IIFFVAILTS LATWVVPVGM FDSQEVQYQV
60 70 80 90 100
DGQTKTRKVV DPHSFRILTN EAGEPEYHRV QLFTTGDERP GLMNFPFEGL
110 120 130 140 150
TSGSKYGTAV GIIMFMLVIG GAFGIVMRTG TIDNGILALI RHTRGNEILF
160 170 180 190 200
IPALFILFSL GGAVFGMGEE AVAFAIIIAP LMVRLGYDSI TTVLVTYIAT
210 220 230 240 250
QIGFASSWMN PFCVVVAQGI AGVPVLSGSG LRIVVWVIAT LIGLIFTMVY
260 270 280 290 300
ASRVKKNPLL SRVHESDRFF REKQADVEQR PFTFGDWLVL IVLTAVMVWV
310 320 330 340 350
IWGVIVNAWF IPEIASQFFT MGLVIGIIGV VFRLNGMTVN TMASSFTEGA
360 370 380 390 400
RMMIAPALLV GFAKGILLLV GNGEAGDASV LNTILNSIAN AISGLDNAVA
410 420 430 440 450
AWFMLLFQAV FNFFVTSGSG QAALTMPLLA PLGDLVGVNR QVTVLAFQFG
460 470 480 490 500
DGFSHIIYPT SASLMATLGV CRVDFRNWLK VGATLLGLLF IMSSVVVIGA

QLMGYH
Length:506
Mass (Da):54,797
Last modified:November 1, 1997 - v2
Checksum:iFA9D2244C19971D5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti1 – 34MSAIT…SLATW → MLFNQPCHL in D17576 (PubMed:7883769).CuratedAdd BLAST34
Sequence conflicti86 – 90GDERP → AMNAR in D17576 (PubMed:7883769).Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75358.2.
AP009048 Genomic DNA. Translation: BAA16137.1.
D17576 Genomic DNA. No translation available.
PIRiH65001.
RefSeqiNP_416801.2. NC_000913.3.
WP_001274493.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75358; AAC75358; b2298.
BAA16137; BAA16137; BAA16137.
GeneIDi946780.
KEGGiecj:JW2295.
eco:b2298.
PATRICi32119967. VBIEscCol129921_2393.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75358.2.
AP009048 Genomic DNA. Translation: BAA16137.1.
D17576 Genomic DNA. No translation available.
PIRiH65001.
RefSeqiNP_416801.2. NC_000913.3.
WP_001274493.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39263.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261493. 212 interactors.
DIPiDIP-11977N.
IntActiP39263. 2 interactors.
MINTiMINT-1315864.
STRINGi511145.b2298.

Protein family/group databases

TCDBi2.A.118.1.8. the basic amino acid antiporter (arcd) family.

Proteomic databases

PaxDbiP39263.
PRIDEiP39263.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75358; AAC75358; b2298.
BAA16137; BAA16137; BAA16137.
GeneIDi946780.
KEGGiecj:JW2295.
eco:b2298.
PATRICi32119967. VBIEscCol129921_2393.

Organism-specific databases

EchoBASEiEB2491.
EcoGeneiEG12607. yfcC.

Phylogenomic databases

eggNOGiENOG4105CSX. Bacteria.
COG1288. LUCA.
HOGENOMiHOG000277481.
InParanoidiP39263.
OMAiTATILHW.
PhylomeDBiP39263.

Enzyme and pathway databases

BioCyciEcoCyc:G7190-MONOMER.
ECOL316407:JW2295-MONOMER.

Miscellaneous databases

PROiP39263.

Family and domain databases

InterProiIPR018385. C4_dicarb_anaerob_car-like.
[Graphical view]
PfamiPF03606. DcuC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFCC_ECOLI
AccessioniPrimary (citable) accession number: P39263
Secondary accession number(s): P76493, P77678
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.