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Protein

Methyl-accepting chemotaxis protein TlpC

Gene

tlpC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducer
Biological processChemotaxis

Enzyme and pathway databases

BioCyciBSUB:BSU03440-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methyl-accepting chemotaxis protein TlpC
Gene namesi
Name:tlpC
Ordered Locus Names:BSU03440
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 13CytoplasmicSequence analysisAdd BLAST13
Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Topological domaini35 – 188ExtracellularSequence analysisAdd BLAST154
Transmembranei189 – 207HelicalSequence analysisAdd BLAST19
Topological domaini208 – 573CytoplasmicSequence analysisAdd BLAST366

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001105611 – 573Methyl-accepting chemotaxis protein TlpCAdd BLAST573

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei276Glutamate methyl ester (Gln)By similarity1
Modified residuei535Glutamate methyl ester (Glu)By similarity1
Modified residuei542Glutamate methyl ester (Glu)By similarity1

Keywords - PTMi

Methylation

Proteomic databases

PaxDbiP39209
PRIDEiP39209

Interactioni

Protein-protein interaction databases

IntActiP39209, 2 interactors
STRINGi224308.Bsubs1_010100001923

Structurei

3D structure databases

ProteinModelPortaliP39209
SMRiP39209
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 261HAMPPROSITE-ProRule annotationAdd BLAST53
Domaini280 – 544Methyl-accepting transducerPROSITE-ProRule annotationAdd BLAST265

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C8Q Bacteria
COG0840 LUCA
HOGENOMiHOG000148080
InParanoidiP39209
KOiK03406
OMAiHIDATIS
PhylomeDBiP39209

Family and domain databases

CDDicd06225 HAMP, 1 hit
InterProiView protein in InterPro
IPR004090 Chemotax_Me-accpt_rcpt
IPR003660 HAMP_dom
IPR004089 MCPsignal_dom
IPR033463 sCache_3
IPR029151 Sensor-like_sf
PfamiView protein in Pfam
PF00015 MCPsignal, 1 hit
PF17202 sCache_3_3, 1 hit
PRINTSiPR00260 CHEMTRNSDUCR
SMARTiView protein in SMART
SM00304 HAMP, 1 hit
SM00283 MA, 1 hit
SUPFAMiSSF103190 SSF103190, 1 hit
PROSITEiView protein in PROSITE
PS50111 CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885 HAMP, 1 hit

Sequencei

Sequence statusi: Complete.

P39209-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIKRFKMKL GTKILCLVFV VILLFSASVG TVMLKEITES MKQMATEKAK
60 70 80 90 100
GDLALSSTYI DDVMSGDWQV KNNKLYKGQT QINGNEDIVD LLGEKTGDTI
110 120 130 140 150
TIFQGDTRVA TNVMKNGERA VGTQASSEVI AAVLKKGKRF YGQADVAGSS
160 170 180 190 200
YQTAYMPLKD QNGNIIGMLY TGANQSILAS LTQSLFTQFA IVLVIVIMVS
210 220 230 240 250
VILVLVFTRK INKRLNALKS AFESAGNGDM TIEVSDKTGD ELSELSVYYN
260 270 280 290 300
KMRMKLNDTI QTVQQSALQL ASASQQLSAG AEETNQASEK ITEAVQQIAN
310 320 330 340 350
GAQDQITRIE NSESSLKQAS ADIRDISANT AAIADKGQLA QSKADIGQKE
360 370 380 390 400
IANVQAQMDA IHQSIQKSGE IIHQLDGRSK QIEQILSVIT QIADQTNLLA
410 420 430 440 450
LNAAIEAARA GEQGKGFAVV ADEVRKLAEE SQQSAGQISK LIIEIQKDMN
460 470 480 490 500
RSARSVEHVK TEAAEGVTMI QRTRDAFKEI AAATGEISAE ISDLSASVTN
510 520 530 540 550
ISASAHQIND SFAANTADIK ESTKNTRQAA ALTEEQFAAM EEITAASETL
560 570
SQLAEELTGI ISQFKMINQA ENG
Length:573
Mass (Da):61,784
Last modified:June 16, 2009 - v3
Checksum:i80E3A90EE35E5CDF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti216N → T in BAA06432 (PubMed:7704255).Curated1
Sequence conflicti216N → T in BAA08978 (PubMed:8969502).Curated1
Sequence conflicti332A → P in BAA06432 (PubMed:7704255).Curated1
Sequence conflicti332A → P in BAA08978 (PubMed:8969502).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z34005 Genomic DNA Translation: CAA83970.1
D30762 Genomic DNA Translation: BAA06432.1
D50453 Genomic DNA Translation: BAA08978.1
AL009126 Genomic DNA Translation: CAB12138.2
PIRiI40496
RefSeqiNP_388226.2, NC_000964.3
WP_003246498.1, NZ_JNCM01000030.1

Genome annotation databases

EnsemblBacteriaiCAB12138; CAB12138; BSU03440
GeneIDi938316
KEGGibsu:BSU03440
PATRICifig|224308.179.peg.361

Similar proteinsi

Entry informationi

Entry nameiTLPC_BACSU
AccessioniPrimary (citable) accession number: P39209
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 16, 2009
Last modified: May 23, 2018
This is version 121 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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