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P39209

- TLPC_BACSU

UniProt

P39209 - TLPC_BACSU

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Protein
Methyl-accepting chemotaxis protein TlpC
Gene
tlpC, BSU03440
Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. signal transducer activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. chemotaxis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transducer

Keywords - Biological processi

Chemotaxis

Enzyme and pathway databases

BioCyciBSUB:BSU03440-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methyl-accepting chemotaxis protein TlpC
Gene namesi
Name:tlpC
Ordered Locus Names:BSU03440
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU03440. [Micado]

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1313Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei14 – 3421Helical; Reviewed prediction
Add
BLAST
Topological domaini35 – 188154Extracellular Reviewed prediction
Add
BLAST
Transmembranei189 – 20719Helical; Reviewed prediction
Add
BLAST
Topological domaini208 – 573366Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 573573Methyl-accepting chemotaxis protein TlpC
PRO_0000110561Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei276 – 2761Glutamate methyl ester (Gln) By similarity
Modified residuei535 – 5351Glutamate methyl ester (Glu) By similarity
Modified residuei542 – 5421Glutamate methyl ester (Glu) By similarity

Keywords - PTMi

Methylation

Proteomic databases

PaxDbiP39209.

Interactioni

Protein-protein interaction databases

IntActiP39209. 2 interactions.
STRINGi224308.BSU03440.

Structurei

3D structure databases

ProteinModelPortaliP39209.
SMRiP39209. Positions 307-568.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini209 – 26153HAMP
Add
BLAST
Domaini280 – 544265Methyl-accepting transducer
Add
BLAST

Sequence similaritiesi

Contains 1 HAMP domain.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0840.
HOGENOMiHOG000148080.
KOiK03406.
OrthoDBiEOG62NX2Z.
PhylomeDBiP39209.

Family and domain databases

InterProiIPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
IPR029151. Sensor-like.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
PRINTSiPR00260. CHEMTRNSDUCR.
SMARTiSM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view]
SUPFAMiSSF103190. SSF103190. 1 hit.
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39209-1 [UniParc]FASTAAdd to Basket

« Hide

MLIKRFKMKL GTKILCLVFV VILLFSASVG TVMLKEITES MKQMATEKAK    50
GDLALSSTYI DDVMSGDWQV KNNKLYKGQT QINGNEDIVD LLGEKTGDTI 100
TIFQGDTRVA TNVMKNGERA VGTQASSEVI AAVLKKGKRF YGQADVAGSS 150
YQTAYMPLKD QNGNIIGMLY TGANQSILAS LTQSLFTQFA IVLVIVIMVS 200
VILVLVFTRK INKRLNALKS AFESAGNGDM TIEVSDKTGD ELSELSVYYN 250
KMRMKLNDTI QTVQQSALQL ASASQQLSAG AEETNQASEK ITEAVQQIAN 300
GAQDQITRIE NSESSLKQAS ADIRDISANT AAIADKGQLA QSKADIGQKE 350
IANVQAQMDA IHQSIQKSGE IIHQLDGRSK QIEQILSVIT QIADQTNLLA 400
LNAAIEAARA GEQGKGFAVV ADEVRKLAEE SQQSAGQISK LIIEIQKDMN 450
RSARSVEHVK TEAAEGVTMI QRTRDAFKEI AAATGEISAE ISDLSASVTN 500
ISASAHQIND SFAANTADIK ESTKNTRQAA ALTEEQFAAM EEITAASETL 550
SQLAEELTGI ISQFKMINQA ENG 573
Length:573
Mass (Da):61,784
Last modified:June 16, 2009 - v3
Checksum:i80E3A90EE35E5CDF
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti216 – 2161N → T in BAA06432. 1 Publication
Sequence conflicti216 – 2161N → T in BAA08978. 1 Publication
Sequence conflicti332 – 3321A → P in BAA06432. 1 Publication
Sequence conflicti332 – 3321A → P in BAA08978. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z34005 Genomic DNA. Translation: CAA83970.1.
D30762 Genomic DNA. Translation: BAA06432.1.
D50453 Genomic DNA. Translation: BAA08978.1.
AL009126 Genomic DNA. Translation: CAB12138.2.
PIRiI40496.
RefSeqiNP_388226.2. NC_000964.3.
WP_003246498.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB12138; CAB12138; BSU03440.
GeneIDi938316.
KEGGibsu:BSU03440.
PATRICi18972251. VBIBacSub10457_0354.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z34005 Genomic DNA. Translation: CAA83970.1 .
D30762 Genomic DNA. Translation: BAA06432.1 .
D50453 Genomic DNA. Translation: BAA08978.1 .
AL009126 Genomic DNA. Translation: CAB12138.2 .
PIRi I40496.
RefSeqi NP_388226.2. NC_000964.3.
WP_003246498.1. NC_000964.3.

3D structure databases

ProteinModelPortali P39209.
SMRi P39209. Positions 307-568.
ModBasei Search...

Protein-protein interaction databases

IntActi P39209. 2 interactions.
STRINGi 224308.BSU03440.

Proteomic databases

PaxDbi P39209.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB12138 ; CAB12138 ; BSU03440 .
GeneIDi 938316.
KEGGi bsu:BSU03440.
PATRICi 18972251. VBIBacSub10457_0354.

Organism-specific databases

GenoListi BSU03440. [Micado ]

Phylogenomic databases

eggNOGi COG0840.
HOGENOMi HOG000148080.
KOi K03406.
OrthoDBi EOG62NX2Z.
PhylomeDBi P39209.

Enzyme and pathway databases

BioCyci BSUB:BSU03440-MONOMER.

Family and domain databases

InterProi IPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
IPR029151. Sensor-like.
[Graphical view ]
Pfami PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view ]
PRINTSi PR00260. CHEMTRNSDUCR.
SMARTi SM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view ]
SUPFAMi SSF103190. SSF103190. 1 hit.
PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of TlpC, a novel 62 kDa MCP-like protein from Bacillus subtilis."
    Hanlon D.W., Rosario M.M.L., Ordal G.W., Venema G., van Sinderen D.
    Microbiology 140:1847-1854(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / OI1085.
  2. "A 10 kb nucleotide sequence at the 5' flanking region (32 degrees) of srfAA of the Bacillus subtilis chromosome."
    Fujishima Y., Yamane K.
    Microbiology 141:277-279(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  3. "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes."
    Yamane K., Kumano M., Kurita K.
    Microbiology 142:3047-3056(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  4. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  5. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
    Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
    Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO 216 AND 332.

Entry informationi

Entry nameiTLPC_BACSU
AccessioniPrimary (citable) accession number: P39209
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 103 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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