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Protein

Carnitine operon protein CaiE

Gene

caiE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Overproduction of CaiE stimulates the activity of CaiB and CaiD.1 Publication

Pathwayi: carnitine metabolism

This protein is involved in the pathway carnitine metabolism, which is part of Amine and polyamine metabolism.
View all proteins of this organism that are known to be involved in the pathway carnitine metabolism and in Amine and polyamine metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyciEcoCyc:CAIE-MONOMER
MetaCyc:CAIE-MONOMER
UniPathwayiUPA00117

Names & Taxonomyi

Protein namesi
Recommended name:
Carnitine operon protein CaiE
Gene namesi
Name:caiE
Ordered Locus Names:b0035, JW5004
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12608 caiE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000687191 – 196Carnitine operon protein CaiEAdd BLAST196

Proteomic databases

PaxDbiP39206
PRIDEiP39206

Interactioni

Protein-protein interaction databases

BioGridi4261465, 163 interactors
STRINGi316385.ECDH10B_0036

Structurei

3D structure databases

ProteinModelPortaliP39206
SMRiP39206
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108Z0R Bacteria
COG0663 LUCA
HOGENOMiHOG000049430
InParanoidiP39206
KOiK08279
OMAiNVQENCT
PhylomeDBiP39206

Family and domain databases

HAMAPiMF_01525 CaiE, 1 hit
InterProiView protein in InterPro
IPR023446 CaiE
IPR001451 Hexapep
IPR011004 Trimer_LpxA-like_sf
PfamiView protein in Pfam
PF00132 Hexapep, 2 hits
SUPFAMiSSF51161 SSF51161, 1 hit

Sequencei

Sequence statusi: Complete.

P39206-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYYAFEGLI PVVHPTAFVH PSAVLIGDVI VGAGVYIGPL ASLRGDYGRL
60 70 80 90 100
IVQAGANIQD GCIMHGYCDT DTIVGENGHI GHGAILHGCL IGRDALVGMN
110 120 130 140 150
SVIMDGAVIG EESIVAAMSF VKAGFRGEKR QLLMGTPARA VRNVSDDELH
160 170 180 190
WKRLNTKEYQ DLVGRCHVSL HETQPLRQME ENRPRLQGTT DVTPKR
Length:196
Mass (Da):21,244
Last modified:December 1, 2000 - v2
Checksum:iBF47443CA7850770
GO

Sequence cautioni

The sequence CAA52115 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti54A → T in strain: O44:K74. 1
Natural varianti90L → V in strain: O44:K74. 1
Natural varianti126R → H in strain: O44:K74. 1
Natural varianti143N → S in strain: O44:K74. 1
Natural varianti153R → Q in strain: O44:K74. 1
Natural varianti168V → A in strain: O44:K74. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73904 Genomic DNA Translation: CAA52115.1 Different initiation.
U00096 Genomic DNA Translation: AAC73146.2
AP009048 Genomic DNA Translation: BAB96604.2
PIRiC64724
RefSeqiNP_414577.2, NC_000913.3
WP_000122871.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73146; AAC73146; b0035
BAB96604; BAB96604; BAB96604
GeneIDi948999
KEGGiecj:JW5004
eco:b0035
PATRICifig|1411691.4.peg.2248

Similar proteinsi

Entry informationi

Entry nameiCAIE_ECOLI
AccessioniPrimary (citable) accession number: P39206
Secondary accession number(s): Q8KMY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: December 1, 2000
Last modified: March 28, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health