Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Carnitine operon protein CaiE

Gene

caiE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Overproduction of CaiE stimulates the activity of CaiB and CaiD.1 Publication

Pathwayi: carnitine metabolism

This protein is involved in the pathway carnitine metabolism, which is part of Amine and polyamine metabolism.
View all proteins of this organism that are known to be involved in the pathway carnitine metabolism and in Amine and polyamine metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciEcoCyc:CAIE-MONOMER.
ECOL316407:JW5004-MONOMER.
MetaCyc:CAIE-MONOMER.
UniPathwayiUPA00117.

Names & Taxonomyi

Protein namesi
Recommended name:
Carnitine operon protein CaiE
Gene namesi
Name:caiE
Ordered Locus Names:b0035, JW5004
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12608. caiE.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 196196Carnitine operon protein CaiEPRO_0000068719Add
BLAST

Proteomic databases

PaxDbiP39206.

Interactioni

Protein-protein interaction databases

BioGridi4261465. 163 interactions.
STRINGi511145.b0035.

Structurei

3D structure databases

ProteinModelPortaliP39206.
SMRiP39206. Positions 1-175.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108Z0R. Bacteria.
COG0663. LUCA.
HOGENOMiHOG000049430.
InParanoidiP39206.
KOiK08279.
OMAiCYEFEGL.
PhylomeDBiP39206.

Family and domain databases

HAMAPiMF_01525. CaiE. 1 hit.
InterProiIPR023446. CaiE.
IPR001451. Hexapep.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00132. Hexapep. 2 hits.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.

Sequencei

Sequence statusi: Complete.

P39206-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYYAFEGLI PVVHPTAFVH PSAVLIGDVI VGAGVYIGPL ASLRGDYGRL
60 70 80 90 100
IVQAGANIQD GCIMHGYCDT DTIVGENGHI GHGAILHGCL IGRDALVGMN
110 120 130 140 150
SVIMDGAVIG EESIVAAMSF VKAGFRGEKR QLLMGTPARA VRNVSDDELH
160 170 180 190
WKRLNTKEYQ DLVGRCHVSL HETQPLRQME ENRPRLQGTT DVTPKR
Length:196
Mass (Da):21,244
Last modified:December 1, 2000 - v2
Checksum:iBF47443CA7850770
GO

Sequence cautioni

The sequence CAA52115 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti54 – 541A → T in strain: O44:K74.
Natural varianti90 – 901L → V in strain: O44:K74.
Natural varianti126 – 1261R → H in strain: O44:K74.
Natural varianti143 – 1431N → S in strain: O44:K74.
Natural varianti153 – 1531R → Q in strain: O44:K74.
Natural varianti168 – 1681V → A in strain: O44:K74.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73904 Genomic DNA. Translation: CAA52115.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73146.2.
AP009048 Genomic DNA. Translation: BAB96604.2.
PIRiC64724.
RefSeqiNP_414577.2. NC_000913.3.
WP_000122871.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73146; AAC73146; b0035.
BAB96604; BAB96604; BAB96604.
GeneIDi948999.
KEGGiecj:JW5004.
eco:b0035.
PATRICi32115165. VBIEscCol129921_0034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73904 Genomic DNA. Translation: CAA52115.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73146.2.
AP009048 Genomic DNA. Translation: BAB96604.2.
PIRiC64724.
RefSeqiNP_414577.2. NC_000913.3.
WP_000122871.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP39206.
SMRiP39206. Positions 1-175.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261465. 163 interactions.
STRINGi511145.b0035.

Proteomic databases

PaxDbiP39206.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73146; AAC73146; b0035.
BAB96604; BAB96604; BAB96604.
GeneIDi948999.
KEGGiecj:JW5004.
eco:b0035.
PATRICi32115165. VBIEscCol129921_0034.

Organism-specific databases

EchoBASEiEB2492.
EcoGeneiEG12608. caiE.

Phylogenomic databases

eggNOGiENOG4108Z0R. Bacteria.
COG0663. LUCA.
HOGENOMiHOG000049430.
InParanoidiP39206.
KOiK08279.
OMAiCYEFEGL.
PhylomeDBiP39206.

Enzyme and pathway databases

UniPathwayiUPA00117.
BioCyciEcoCyc:CAIE-MONOMER.
ECOL316407:JW5004-MONOMER.
MetaCyc:CAIE-MONOMER.

Miscellaneous databases

PROiP39206.

Family and domain databases

HAMAPiMF_01525. CaiE. 1 hit.
InterProiIPR023446. CaiE.
IPR001451. Hexapep.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00132. Hexapep. 2 hits.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCAIE_ECOLI
AccessioniPrimary (citable) accession number: P39206
Secondary accession number(s): Q8KMY1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: December 1, 2000
Last modified: September 7, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.