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Protein

Universal stress protein G

Gene

uspG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. adenylate kinase activity Source: EcoliWiki

GO - Biological processi

  1. nucleotide phosphorylation Source: GOC
  2. protein adenylylation Source: EcoliWiki
  3. protein autophosphorylation Source: EcoliWiki
  4. regulation of cell motility Source: EcoCyc
  5. response to stress Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Stress response

Enzyme and pathway databases

BioCyciEcoCyc:G6334-MONOMER.
ECOL316407:JW0600-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Universal stress protein G
Gene namesi
Name:uspG
Synonyms:ybdQ, yzzU
Ordered Locus Names:b0607, JW0600
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG12683. uspG.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: EcoliWiki
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 142142Universal stress protein GPRO_0000147432Add
BLAST

Proteomic databases

PaxDbiP39177.
PRIDEiP39177.

2D gel databases

SWISS-2DPAGEP39177.

Expressioni

Inductioni

By starvation, heat shock and in response to some toxic agents.1 Publication

Gene expression databases

GenevestigatoriP39177.

Interactioni

Subunit structurei

Interacts with GroEL.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
groLP0A6F54EBI-561722,EBI-543750

Protein-protein interaction databases

DIPiDIP-11354N.
IntActiP39177. 78 interactions.
STRINGi511145.b0607.

Structurei

3D structure databases

ProteinModelPortaliP39177.
SMRiP39177. Positions 5-142.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal stress protein A family.Curated

Phylogenomic databases

eggNOGiCOG0589.
HOGENOMiHOG000238897.
InParanoidiP39177.
KOiK11932.
OMAiIIHLLHV.
OrthoDBiEOG6CCH61.
PhylomeDBiP39177.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PRINTSiPR01438. UNVRSLSTRESS.

Sequencei

Sequence statusi: Complete.

P39177-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKTIIMPVD VFEMELSDKA VRHAEFLAQD DGVIHLLHVL PGSASLSLHR
60 70 80 90 100
FAADVRRFEE HLQHEAQERL QTMVSHFTID PSRIKQHVRF GSVRDEVNEL
110 120 130 140
AEELGADVVV IGSRNPSIST HLLGSNASSV IRHANLPVLV VR
Length:142
Mass (Da):15,935
Last modified:November 1, 1997 - v2
Checksum:i9BF5F7E7BBD51467
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40808.1.
U00096 Genomic DNA. Translation: AAC73708.1.
AP009048 Genomic DNA. Translation: BAA35237.1.
PIRiE64794.
RefSeqiNP_415140.1. NC_000913.3.
YP_488897.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC73708; AAC73708; b0607.
BAA35237; BAA35237; BAA35237.
GeneIDi12930900.
945229.
KEGGiecj:Y75_p0597.
eco:b0607.
PATRICi32116394. VBIEscCol129921_0637.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40808.1.
U00096 Genomic DNA. Translation: AAC73708.1.
AP009048 Genomic DNA. Translation: BAA35237.1.
PIRiE64794.
RefSeqiNP_415140.1. NC_000913.3.
YP_488897.1. NC_007779.1.

3D structure databases

ProteinModelPortaliP39177.
SMRiP39177. Positions 5-142.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-11354N.
IntActiP39177. 78 interactions.
STRINGi511145.b0607.

2D gel databases

SWISS-2DPAGEP39177.

Proteomic databases

PaxDbiP39177.
PRIDEiP39177.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73708; AAC73708; b0607.
BAA35237; BAA35237; BAA35237.
GeneIDi12930900.
945229.
KEGGiecj:Y75_p0597.
eco:b0607.
PATRICi32116394. VBIEscCol129921_0637.

Organism-specific databases

EchoBASEiEB2547.
EcoGeneiEG12683. uspG.

Phylogenomic databases

eggNOGiCOG0589.
HOGENOMiHOG000238897.
InParanoidiP39177.
KOiK11932.
OMAiIIHLLHV.
OrthoDBiEOG6CCH61.
PhylomeDBiP39177.

Enzyme and pathway databases

BioCyciEcoCyc:G6334-MONOMER.
ECOL316407:JW0600-MONOMER.

Miscellaneous databases

PROiP39177.

Gene expression databases

GenevestigatoriP39177.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PRINTSiPR01438. UNVRSLSTRESS.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12."
    Link A.J., Robison K., Church G.M.
    Electrophoresis 18:1259-1313(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-12.
    Strain: K12 / EMG2.
  6. Cited for: PROTEIN SEQUENCE OF 1-11.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  7. Cited for: PROTEIN SEQUENCE OF 1-4.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  8. "The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage."
    Gustavsson N., Diez A., Nystroem T.
    Mol. Microbiol. 43:107-117(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
  9. "Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL."
    Bochkareva E.S., Girshovich A.S., Bibi E.
    Eur. J. Biochem. 269:3032-3040(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, INTERACTION WITH GROEL.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

Entry informationi

Entry nameiUSPG_ECOLI
AccessioniPrimary (citable) accession number: P39177
Secondary accession number(s): P77720
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1997
Last modified: March 4, 2015
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.