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P39177

- USPG_ECOLI

UniProt

P39177 - USPG_ECOLI

Protein

Universal stress protein G

Gene

uspG

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. adenylate kinase activity Source: EcoliWiki
    2. protein binding Source: IntAct

    GO - Biological processi

    1. nucleotide phosphorylation Source: GOC
    2. protein adenylylation Source: EcoliWiki
    3. protein autophosphorylation Source: EcoliWiki
    4. regulation of cell motility Source: EcoCyc
    5. response to stress Source: UniProtKB-KW

    Keywords - Biological processi

    Stress response

    Enzyme and pathway databases

    BioCyciEcoCyc:G6334-MONOMER.
    ECOL316407:JW0600-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Universal stress protein G
    Gene namesi
    Name:uspG
    Synonyms:ybdQ, yzzU
    Ordered Locus Names:b0607, JW0600
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG12683. uspG.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: EcoliWiki

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 142142Universal stress protein GPRO_0000147432Add
    BLAST

    Proteomic databases

    PaxDbiP39177.
    PRIDEiP39177.

    2D gel databases

    SWISS-2DPAGEP39177.

    PTM databases

    PhosSiteiP0810449.

    Expressioni

    Inductioni

    By starvation, heat shock and in response to some toxic agents.1 Publication

    Gene expression databases

    GenevestigatoriP39177.

    Interactioni

    Subunit structurei

    Interacts with GroEL.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    groLP0A6F54EBI-561722,EBI-543750

    Protein-protein interaction databases

    DIPiDIP-11354N.
    IntActiP39177. 78 interactions.
    STRINGi511145.b0607.

    Structurei

    3D structure databases

    ProteinModelPortaliP39177.
    SMRiP39177. Positions 5-142.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the universal stress protein A family.Curated

    Phylogenomic databases

    eggNOGiCOG0589.
    HOGENOMiHOG000238897.
    KOiK11932.
    OMAiIIHLLHV.
    OrthoDBiEOG6CCH61.
    PhylomeDBiP39177.

    Family and domain databases

    Gene3Di3.40.50.620. 1 hit.
    InterProiIPR014729. Rossmann-like_a/b/a_fold.
    IPR006015. Universal_stress_UspA.
    IPR006016. UspA.
    [Graphical view]
    PfamiPF00582. Usp. 1 hit.
    [Graphical view]
    PRINTSiPR01438. UNVRSLSTRESS.

    Sequencei

    Sequence statusi: Complete.

    P39177-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYKTIIMPVD VFEMELSDKA VRHAEFLAQD DGVIHLLHVL PGSASLSLHR    50
    FAADVRRFEE HLQHEAQERL QTMVSHFTID PSRIKQHVRF GSVRDEVNEL 100
    AEELGADVVV IGSRNPSIST HLLGSNASSV IRHANLPVLV VR 142
    Length:142
    Mass (Da):15,935
    Last modified:November 1, 1997 - v2
    Checksum:i9BF5F7E7BBD51467
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U82598 Genomic DNA. Translation: AAB40808.1.
    U00096 Genomic DNA. Translation: AAC73708.1.
    AP009048 Genomic DNA. Translation: BAA35237.1.
    PIRiE64794.
    RefSeqiNP_415140.1. NC_000913.3.
    YP_488897.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC73708; AAC73708; b0607.
    BAA35237; BAA35237; BAA35237.
    GeneIDi12930900.
    945229.
    KEGGiecj:Y75_p0597.
    eco:b0607.
    PATRICi32116394. VBIEscCol129921_0637.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U82598 Genomic DNA. Translation: AAB40808.1 .
    U00096 Genomic DNA. Translation: AAC73708.1 .
    AP009048 Genomic DNA. Translation: BAA35237.1 .
    PIRi E64794.
    RefSeqi NP_415140.1. NC_000913.3.
    YP_488897.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P39177.
    SMRi P39177. Positions 5-142.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-11354N.
    IntActi P39177. 78 interactions.
    STRINGi 511145.b0607.

    PTM databases

    PhosSitei P0810449.

    2D gel databases

    SWISS-2DPAGE P39177.

    Proteomic databases

    PaxDbi P39177.
    PRIDEi P39177.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC73708 ; AAC73708 ; b0607 .
    BAA35237 ; BAA35237 ; BAA35237 .
    GeneIDi 12930900.
    945229.
    KEGGi ecj:Y75_p0597.
    eco:b0607.
    PATRICi 32116394. VBIEscCol129921_0637.

    Organism-specific databases

    EchoBASEi EB2547.
    EcoGenei EG12683. uspG.

    Phylogenomic databases

    eggNOGi COG0589.
    HOGENOMi HOG000238897.
    KOi K11932.
    OMAi IIHLLHV.
    OrthoDBi EOG6CCH61.
    PhylomeDBi P39177.

    Enzyme and pathway databases

    BioCyci EcoCyc:G6334-MONOMER.
    ECOL316407:JW0600-MONOMER.

    Miscellaneous databases

    PROi P39177.

    Gene expression databases

    Genevestigatori P39177.

    Family and domain databases

    Gene3Di 3.40.50.620. 1 hit.
    InterProi IPR014729. Rossmann-like_a/b/a_fold.
    IPR006015. Universal_stress_UspA.
    IPR006016. UspA.
    [Graphical view ]
    Pfami PF00582. Usp. 1 hit.
    [Graphical view ]
    PRINTSi PR01438. UNVRSLSTRESS.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. "Sequence of minutes 4-25 of Escherichia coli."
      Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
      Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    5. "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12."
      Link A.J., Robison K., Church G.M.
      Electrophoresis 18:1259-1313(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-12.
      Strain: K12 / EMG2.
    6. Cited for: PROTEIN SEQUENCE OF 1-11.
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    7. Cited for: PROTEIN SEQUENCE OF 1-4.
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    8. "The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage."
      Gustavsson N., Diez A., Nystroem T.
      Mol. Microbiol. 43:107-117(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE NAME.
      Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
    9. "Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL."
      Bochkareva E.S., Girshovich A.S., Bibi E.
      Eur. J. Biochem. 269:3032-3040(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, INTERACTION WITH GROEL.
      Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

    Entry informationi

    Entry nameiUSPG_ECOLI
    AccessioniPrimary (citable) accession number: P39177
    Secondary accession number(s): P77720
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 108 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3