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Protein

Putative glucose-6-phosphate 1-epimerase

Gene

yeaD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei74SubstrateBy similarity1
Binding sitei99SubstrateBy similarity1
Active sitei164By similarity1
Binding sitei208SubstrateBy similarity1
Active sitei267By similarity1

GO - Molecular functioni

GO - Biological processi

  • carbohydrate metabolic process Source: InterPro
  • cellular response to DNA damage stimulus Source: EcoliWiki

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyciEcoCyc:G6966-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glucose-6-phosphate 1-epimeraseBy similarity (EC:5.1.3.15By similarity)
Alternative name(s):
Putative D-hexose-6-phosphate mutarotaseBy similarity
Unknown protein from 2D-page spots T26/PR37
Gene namesi
Name:yeaD
Synonyms:yzzQ
Ordered Locus Names:b1780, JW1769
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12679 yeaD

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002130361 – 294Putative glucose-6-phosphate 1-epimeraseAdd BLAST294

Proteomic databases

EPDiP39173
PaxDbiP39173
PRIDEiP39173

Interactioni

Subunit structurei

Monomer in solution.1 Publication

Protein-protein interaction databases

BioGridi4260309, 34 interactors
IntActiP39173, 2 interactors
STRINGi316385.ECDH10B_1918

Structurei

3D structure databases

ProteinModelPortaliP39173
SMRiP39173
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105DSB Bacteria
COG0676 LUCA
HOGENOMiHOG000283048
InParanoidiP39173
KOiK01792
OMAiTQALHSY
PhylomeDBiP39173

Family and domain databases

CDDicd09020 D-hex-6-P-epi_like, 1 hit
Gene3Di2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR008183 Aldose_1/G6P_1-epimerase
IPR025532 G6P_1-epimerase
IPR011013 Gal_mutarotase_sf_dom
IPR014718 GH-type_carb-bd
PfamiView protein in Pfam
PF01263 Aldose_epim, 1 hit
PIRSFiPIRSF016020 PHexose_mutarotase, 1 hit
SUPFAMiSSF74650 SSF74650, 1 hit

Sequencei

Sequence statusi: Complete.

P39173-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKKIFALPV IEQISPVLSR RKLDELDLIV VDHPQVKASF ALQGAHLLSW
60 70 80 90 100
KPAGEEEVLW LSNNTPFKNG VAIRGGVPVC WPWFGPAAQQ GLPAHGFARN
110 120 130 140 150
LPWTLKSHHE DADGVALTFE LTQSEETKKF WPHDFTLLAH FRVGKTCEID
160 170 180 190 200
LESHGEFETT SALHTYFNVG DIAKVSVSGL GDRFIDKVND AKENVLTDGI
210 220 230 240 250
QTFPDRTDRV YLNPQDCSVI NDEALNRIIA VGHQHHLNVV GWNPGPALSI
260 270 280 290
SMGDMPDDGY KTFVCVETAY ASETQKVTKE KPAHLAQSIR VAKR
Length:294
Mass (Da):32,666
Last modified:November 1, 1997 - v2
Checksum:iADACFE6D46F20957
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74850.2
AP009048 Genomic DNA Translation: BAA15577.1
PIRiD64938
RefSeqiNP_416294.4, NC_000913.3
WP_001335909.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74850; AAC74850; b1780
BAA15577; BAA15577; BAA15577
GeneIDi946572
KEGGiecj:JW1769
eco:b1780
PATRICifig|511145.12.peg.1853

Similar proteinsi

Entry informationi

Entry nameiYEAD_ECOLI
AccessioniPrimary (citable) accession number: P39173
Secondary accession number(s): P76233, P76913
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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