Reviewed, UniProtKB/Swiss-Prot P39173 (YEAD_ECOLI)

Names and origin

Protein names

Recommended name:
    UPF0010 protein yeaD
Alternative name(s):
    Unknown protein from 2D-page spots T26/PR37

Gene names

Name:	yeaD
Synonyms:	yzzQ
Ordered Locus Names:	b1780, JW1769

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0010 (mutarotase-related) family.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	UPF0010 protein yeaD		PRO_0000213036
Sites
	Active site	164	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	P39173-1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: ADACFE6D46F20957	FASTA	294	32,666
	10 20 30 40 50 60 MIKKIFALPV IEQISPVLSR RKLDELDLIV VDHPQVKASF ALQGAHLLSW KPAGEEEVLW 70 80 90 100 110 120 LSNNTPFKNG VAIRGGVPVC WPWFGPAAQQ GLPAHGFARN LPWTLKSHHE DADGVALTFE 130 140 150 160 170 180 LTQSEETKKF WPHDFTLLAH FRVGKTCEID LESHGEFETT SALHTYFNVG DIAKVSVSGL 190 200 210 220 230 240 GDRFIDKVND AKENVLTDGI QTFPDRTDRV YLNPQDCSVI NDEALNRIIA VGHQHHLNVV 250 260 270 280 290 GWNPGPALSI SMGDMPDDGY KTFVCVETAY ASETQKVTKE KPAHLAQSIR VAKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:379-392(1996) [PubMed: 9097040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Link A.J., Robison K., Church G.M. Electrophoresis 18:1259-1313(1997) [PubMed: 9298646] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-12. Strain: K12 / EMG2.
[5]	"Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography." Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B. Electrophoresis 20:2181-2195(1999) [PubMed: 10493123] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC74850.1. Different initiation. AP009048 Genomic DNA. Translation: BAA15577.1.
PIR	D64938.
RefSeq	AP_002399.1. NP_416294.4.
3D structure databases
SMR	P39173. Positions 1-294.
ModBase	Search...
Protein-protein interaction databases
STRING	P39173.
Genome annotation databases
GeneID	946572.
GenomeReviews	Gene locus JW1769 in contig AP009048_GR. Gene locus b1780 in contig U00096_GR.
KEGG	ecj:JW1769. eco:b1780.
Organism-specific databases
EchoBASE	EB2544.
EcoGene	EG12679. yeaD.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG737737.
OMA	QALHTYF.
Enzyme and pathway databases
BioCyc	EcoCyc:G6966-MON. ECOL168927:B1780-MON.
Gene expression databases
Genevestigator	P39173.
Family and domain databases
InterPro	IPR008183. Ald1_epimerase. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YEAD_ECOLI

Accession

Primary (citable) accession number: P39173
Secondary accession number(s): P76233, P76913

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	November 1, 1997
Last modified:	December 15, 2009
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)