Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uxu operon transcriptional regulator

Gene

uxuR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Repressor for the uxuRBA operon.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi36 – 55H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG20249-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uxu operon transcriptional regulator
Gene namesi
Name:uxuR
Ordered Locus Names:b4324, JW4287
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20249. uxuR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000506701 – 257Uxu operon transcriptional regulatorAdd BLAST257

Proteomic databases

PaxDbiP39161.
PRIDEiP39161.

Interactioni

Protein-protein interaction databases

BioGridi4261007. 10 interactors.
DIPiDIP-11110N.
IntActiP39161. 2 interactors.
STRINGi316407.85677067.

Structurei

3D structure databases

ProteinModelPortaliP39161.
SMRiP39161.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 76HTH gntR-typePROSITE-ProRule annotationAdd BLAST69

Phylogenomic databases

eggNOGiENOG4105C6F. Bacteria.
COG2186. LUCA.
HOGENOMiHOG000273991.
InParanoidiP39161.
KOiK13637.
PhylomeDBiP39161.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiView protein in InterPro
IPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
PRINTSiPR00035. HTHGNTR.
SMARTiView protein in SMART
SM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF48008. SSF48008. 1 hit.
PROSITEiView protein in PROSITE
PS50949. HTH_GNTR. 1 hit.

Sequencei

Sequence statusi: Complete.

P39161-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSATSAQRP YQEVGAMIRD LIIKTPYNPG ERLPPEREIA EMLDVTRTVV
60 70 80 90 100
REALIMLEIK GLVEVRRGAG IYVLDNSGSQ NTDSPDANVC NDAGPFELLQ
110 120 130 140 150
ARQLLESNIA EFAALQATRE DIVKMRQALQ LEERELASSA PGSSESGDMQ
160 170 180 190 200
FHLAIAEATH NSMLVELFRQ SWQWRENNPM WIQLHSHLDD SLYRKEWLGD
210 220 230 240 250
HKQILAALIK KDARAAKLAM WQHLENVKQR LLEFSNVDDI YFDGYLFDSW

PLDKVDA
Length:257
Mass (Da):29,308
Last modified:February 1, 1995 - v1
Checksum:iFA9A64922E5F5F5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13329 Genomic DNA. Translation: BAA02592.1.
U14003 Genomic DNA. Translation: AAA97220.1.
U00096 Genomic DNA. Translation: AAC77280.1.
AP009048 Genomic DNA. Translation: BAE78317.1.
PIRiS56549.
RefSeqiNP_418744.1. NC_000913.3.
WP_000833679.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77280; AAC77280; b4324.
BAE78317; BAE78317; BAE78317.
GeneIDi948849.
KEGGiecj:JW4287.
eco:b4324.
PATRICifig|511145.12.peg.4466.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiUXUR_ECOLI
AccessioniPrimary (citable) accession number: P39161
Secondary accession number(s): Q2M5Y9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 5, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene