Reviewed,
UniProtKB/Swiss-Prot P39160 (UXUB_ECOLI)
Last modified
November 25, 2008.
Version 65.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: D-mannonate oxidoreductase EC=1.1.1.57 Alternative name(s): Fructuronate reductase | ||||
| Gene names |
| ||||
| Organism | Escherichia coli (strain K12) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83333 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 486 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | D-mannonate + NAD(+) = D-fructuronate + NADH. |
| Pathway | Carbohydrate metabolism; pentose and glucuronate interconversion. |
| Sequence similarities | Belongs to the mannitol dehydrogenase family. UxuB subfamily. |
Ontologies
Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | coenzyme binding Inferred from electronic annotation. Source: InterPro fructuronate reductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| D13329 Genomic DNA. Translation: BAA02591.1. U14003 Genomic DNA. Translation: AAA97219.1. U00096 Genomic DNA. Translation: AAC77279.1. AP009048 Genomic DNA. Translation: BAE78316.1. | |
| PIR | S56548. |
| RefSeq | AP_004815.1. NP_418743.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1LJ8 based on UniProtKB O08355. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:11109N. |
Genome annotation databases | |
| GeneID | 946795. |
| GenomeReviews | Gene locus b4323 in contig U00096_GR. Gene locus JW4286 in contig AP009048_GR. |
| KEGG | ecj:JW4286. eco:b4323. |
Organism-specific databases | |
| EchoBASE | EB4150. |
| EcoGene | EG20248. uxuB. |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P39160. |
Enzyme and pathway databases | |
| BioCyc | EcoCyc:MANNONOXIDOREDUCT-MON. MetaCyc:MANNONOXIDOREDUCT-MON. |
Family and domain databases | |
| InterPro | IPR013328. DHase_multihelical. IPR013118. Mannitol_DHase_C. IPR000669. Mannitol_DHase_core. IPR013131. Mannitol_DHase_N. IPR016040. NAD(P)-bd. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit. |
| Pfam | PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view] |
| PRINTS | PR00084. MTLDHDRGNASE. |
| PROSITE | PS00974. MANNITOL_DHGENASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UXUB_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P39160 Secondary accession number(s): Q2M5Z0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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