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P39130 (LPLD_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative glucosidase lplD
EC=3.2.1.-
Gene names
Name:lplD
Ordered Locus Names:BSU07130
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length446 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Cofactor

NAD By similarity.

Divalent metal ion By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 4 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 446446Putative glucosidase lplD
PRO_0000169862

Regions

Nucleotide binding10 – 7263NAD By similarity

Sites

Active site1741Proton donor By similarity
Metal binding1731Manganese By similarity
Metal binding2101Manganese By similarity
Binding site1511Substrate By similarity

Experimental info

Sequence conflict661R → T in AAA22577. Ref.1
Sequence conflict1541S → Y in AAA22577. Ref.1

Secondary structure

1 ........................................................... 446
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P39130 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: 691FEC5C371B9F5B

FASTA44649,487
        10         20         30         40         50         60 
MFHISTLDQI KIAYIGGGSQ GWARSLMSDL SIDERMSGTV ALYDLDFEAA QKNEVIGNHS 

        70         80         90        100        110        120 
GNGRWRYEAV STLKKALSAA DIVIISILPG SLDDMEVDVH LPERCGIYQS VGDTVGPGGI 

       130        140        150        160        170        180 
IRGLRAVPIF AEIARAIRDY APESWVINYT NPMSVCTRVL YKVFPGIKAI GCCHEVFGTQ 

       190        200        210        220        230        240 
KLLAEMVTER LGIEVPRRED IRVNVLGINH FTWITKASYR HIDLLPIFRE FSAHYGESGY 

       250        260        270        280        290        300 
ELEGECWRDS VFCSAHRVAF DLFETYGAIP AAGDRHLAEF LPGPYLKQPE VWKFHLTPIS 

       310        320        330        340        350        360 
FRKQDRAEKR QETERLIVQQ RGVAEKASGE EGVNIIAALL GLGELVTNVN MPNQGQVLNL 

       370        380        390        400        410        420 
PIQAIVETNA FITRNRVQPI LSGALPKGVE MLAARHISNQ EAVADAGLTK DTGLAFQAFL 

       430        440 
NDPLVQIDRS DAEQLFNDML QCIMQS

« Hide

References

« Hide 'large scale' references
[1]"The complete lpl cluster of Bacillus subtilis."
Gomez A., Ramon D., Sanz P.
Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB 3610 / VKM B-501.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L19165 Genomic DNA. Translation: AAA22577.1.
AL009126 Genomic DNA. Translation: CAB12532.1.
PIRC69653.
RefSeqNP_388594.1. NC_000964.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3FEFX-ray2.20A/B/C/D7-446[»]
ProteinModelPortalP39130.
SMRP39130. Positions 7-440.
ModBaseSearch...

Protein family/group databases

CAZyGH4. Glycoside Hydrolase Family 4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000002658; EBBACP00000002658; EBBACG00000002653.
GeneID938770.
GenomeReviewsGene locus BSU07130 in contig AL009126_GR.
KEGGbsu:BSU07130.
NMPDRfig|224308.1.peg.713.
PATRIC18973074. VBIBacSub10457_0751.

Organism-specific databases

GenoListBSU07130. [Micado]

Phylogenomic databases

GeneTreeEBGT00050000000927.
HOGENOMHBG312615.
OMAPEKYGIY.
PhylomeDBP39130.
ProtClustDBCLSK886832.

Enzyme and pathway databases

BioCycBSUB:BSU07130-MONOMER.

Family and domain databases

InterProIPR019802. GlycHydrolase_4_CS.
IPR001088. Glyco_hydro_4.
IPR022616. Glyco_hydro_4_C.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.90.110.10. lact_mal_DH. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF02056. Glyco_hydro_4. 1 hit.
PF11975. Glyco_hydro_4C. 1 hit.
[Graphical view]
PRINTSPR00732. GLHYDRLASE4.
SUPFAMSSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
PROSITEPS01324. GLYCOSYL_HYDROL_F4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLPLD_BACSU
AccessionPrimary (citable) accession number: P39130
Secondary accession number(s): O31532
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: December 15, 1998
Last modified: January 25, 2012
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents