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P39125 (GLGA_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:BSU30950
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length484 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Induction

Expressed exclusively on media containing carbon sources that allow efficient sporulation. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 484484Glycogen synthase HAMAP-Rule MF_00484
PRO_0000188597

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
P39125 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: D479E8064818E0E4

FASTA48455,857
        10         20         30         40         50         60 
MKILFAVSEC TPFVKSGGLA DVAGALPKAL ARLGNEVAVM LPKYSQIPEP WKKRMKKQAE 

        70         80         90        100        110        120 
CTVAVGWRQQ YCGIEHMAEN DVNYYFIDNE YYFNRDSLYG HYDDGERFAF FSRAVLEAAK 

       130        140        150        160        170        180 
VVNVQADIVH THDWHTAMVN YLLKEEYRKH PFYERMKSVL TIHNLQFQGI FPPDVTHDLL 

       190        200        210        220        230        240 
GLEMDHFHYE RLECNGFVNF MKAGIIAADH VTTVSPTYRN EIMTPYYGEQ LEQVLQYRED 

       250        260        270        280        290        300 
DVTGILNGID DTFYQPKSDP YIEAQYDSGD LACKLENKTK LQQRMGLPEK NDIPLISMVT 

       310        320        330        340        350        360 
RLTKQKGLDL VRRIMHELLE EQDIQLVVLG TGEREFEDYF RYAEFAFHEK CRAYIGFDEP 

       370        380        390        400        410        420 
LAHQIYAGSD MFLMPSKFEP CGLGQLIALQ YGAIPIVRET GGLYDTVRAY QEEEGTGNGF 

       430        440        450        460        470        480 
TFSAFNAHDL KFTIERALSF YCQQDVWKSI VKTAMNADYS WGKSAKEYQR IFEQVTRSGR 


DVLE 

« Hide

References

« Hide 'large scale' references
[1]"Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation."
Kiel J.A.K.W., Boels J.M., Beldman G., Venema G.
Mol. Microbiol. 11:203-218(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region."
Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.
Microbiology 143:3431-3441(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z25795 Genomic DNA. Translation: CAA81043.1.
AF008220 Genomic DNA. Translation: AAC00217.1.
AL009126 Genomic DNA. Translation: CAB15073.1.
PIRS40051.
RefSeqNP_390973.1. NC_000964.3.

3D structure databases

ProteinModelPortalP39125.
SMRP39125. Positions 1-478.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224308.BSU30950.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Proteomic databases

PaxDbP39125.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB15073; CAB15073; BSU30950.
GeneID936781.
KEGGbsu:BSU30950.
PATRIC18978096. VBIBacSub10457_3236.

Organism-specific databases

GenoListBSU30950. [Micado]

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAPYHDESQ.
OrthoDBEOG6JTC6Z.
PhylomeDBP39125.

Enzyme and pathway databases

BioCycBSUB:BSU30950-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_BACSU
AccessionPrimary (citable) accession number: P39125
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 9, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList