Reviewed,
UniProtKB/Swiss-Prot P39121 (DEOC_BACSU)
Last modified
June 16, 2009.
Version 74.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Deoxyribose-phosphate aldolase EC=4.1.2.4 Alternative name(s): Phosphodeoxyriboaldolase Short name=Deoxyriboaldolase Short name=DERA | ||||||
| Gene names |
| ||||||
| Organism | Bacillus subtilis [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 1423 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 211 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 |
| Pathway | Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 |
| Subcellular location | |
| Sequence similarities | Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | Schiff base |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic processInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 211 | 211 | Deoxyribose-phosphate aldolase HAMAP MF_00114 | PRO_0000057224 | |||||
Sites | |||||||||
| Active site | 152 | 1 | Schiff-base intermediate with acetaldehyde By similarity | ||||||
| Active site | 181 | 1 | By similarity | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Dra-nupC-pdp operon of Bacillus subtilis: nucleotide sequence, induction by deoxyribonucleosides, and transcriptional regulation by the deoR-encoded DeoR repressor protein." Saxild H.H., Andersen L.N., Hammer K. J. Bacteriol. 178:424-434(1996) [PubMed: 8550462] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [2] | "Cloning and sequencing of a 23-kb region of the Bacillus subtilis genome between the iol and hut operons." Yoshida K., Fujimyra M., Yanai N., Fujita Y. DNA Res. 2:295-301(1995) [PubMed: 8867804] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168 / BGSC1A1. |
| [3] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.  Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
Cross-references
Sequence databases | |
|---|---|
| X82174 Genomic DNA. Translation: CAA57662.1. Different initiation. D45912 Genomic DNA. Translation: BAA08337.1. Z99124 Genomic DNA. Translation: CAB15978.1. | |
| PIR | A69619. |
| RefSeq | NP_391821.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1O0Y based on UniProtKB Q9X1P5. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 938608. |
| GenomeReviews | Gene locus BSU39420 in contig AL009126_GR. |
| KEGG | bsu:BSU39420. |
| NMPDR | fig|224308.1.peg.3947. |
Organism-specific databases | |
| SubtiList | BG10983. deoC. [Micado] |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P39121. |
| OMA | P39121. AKMIDHT. |
Enzyme and pathway databases | |
| BioCyc | BSUB224308:BSU3938-MON. |
| BRENDA | 4.1.2.4. 150. |
Family and domain databases | |
| HAMAP | MF_00114. [Tree] |
| InterPro | IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| PANTHER | PTHR10889. DeoC. 1 hit. |
| Pfam | PF01791. DeoC. 1 hit. [Graphical view] |
| PIRSF | PIRSF001357. DeoC. 1 hit. |
| TIGRFAMs | TIGR00126. deoC. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | DEOC_BACSU | ||||||||
| Accession | Primary (citable) accession number: P39121 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |
