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Protein

GTP-binding protein CIN4

Gene

CIN4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Implicated in yeast microtubule function.

Miscellaneous

Present with 468 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30GTPBy similarity8
Nucleotide bindingi69 – 73GTPBy similarity5
Nucleotide bindingi131 – 134GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

  • protein folding Source: SGD
  • small GTPase mediated signal transduction Source: InterPro
  • tubulin complex assembly Source: SGD

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-32831-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein CIN4
Alternative name(s):
Chromosome instability protein 4
Gene namesi
Name:CIN4
Synonyms:GTP1, UGX1
Ordered Locus Names:YMR138W
ORF Names:YM9375.07
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR138W.
SGDiS000004746. CIN4.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001224641 – 191GTP-binding protein CIN4Add BLAST191

Proteomic databases

MaxQBiP39110.
PRIDEiP39110.

Interactioni

Protein-protein interaction databases

BioGridi35315. 106 interactors.
DIPiDIP-1256N.
IntActiP39110. 6 interactors.
MINTiMINT-404656.
STRINGi4932.YMR138W.

Structurei

3D structure databases

ProteinModelPortaliP39110.
SMRiP39110.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00890000140715.
HOGENOMiHOG000163691.
InParanoidiP39110.
KOiK07943.
OMAiEIRCLIL.
OrthoDBiEOG092C508L.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51417. ARF. 1 hit.

Sequencei

Sequence statusi: Complete.

P39110-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLSIIRKQ KLRDKEIRCL ILGLDNSGKS TIVNKLLPKD EQNNDGIMPT
60 70 80 90 100
VGFQIHSLMI KDVTISLWDI GGQRTLRPFW DNYFDKTQAM IWCIDVSLSM
110 120 130 140 150
RFDETLQELK ELINRDENRI GYECAVIVVL NKIDLVEDKS ELHRRCLLVE
160 170 180 190
SELKCLFKPD IRIELVKCSG VTGEGIDNLR DRLVESCHFT Q
Length:191
Mass (Da):22,067
Last modified:February 1, 1995 - v1
Checksum:iCF30AF932A2D2566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36669 Genomic DNA. Translation: AAA50350.1.
X77086 Genomic DNA. Translation: CAA54358.1.
Z47071 Genomic DNA. Translation: CAA87352.1.
AY558409 Genomic DNA. Translation: AAS56735.1.
BK006946 Genomic DNA. Translation: DAA10035.1.
PIRiS51496.
RefSeqiNP_013858.1. NM_001182640.1.

Genome annotation databases

EnsemblFungiiYMR138W; YMR138W; YMR138W.
GeneIDi855169.
KEGGisce:YMR138W.

Similar proteinsi

Entry informationi

Entry nameiCIN4_YEAST
AccessioniPrimary (citable) accession number: P39110
Secondary accession number(s): D6VZW1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 27, 2017
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names