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Protein

GTP-binding protein CIN4

Gene

CIN4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Implicated in yeast microtubule function.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30GTPBy similarity8
Nucleotide bindingi69 – 73GTPBy similarity5
Nucleotide bindingi131 – 134GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

  • protein folding Source: SGD
  • small GTPase mediated signal transduction Source: InterPro
  • tubulin complex assembly Source: SGD
Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-32831-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein CIN4
Alternative name(s):
Chromosome instability protein 4
Gene namesi
Name:CIN4
Synonyms:GTP1, UGX1
Ordered Locus Names:YMR138W
ORF Names:YM9375.07
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR138W.
SGDiS000004746. CIN4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001224641 – 191GTP-binding protein CIN4Add BLAST191

Proteomic databases

MaxQBiP39110.
PRIDEiP39110.

Interactioni

Protein-protein interaction databases

BioGridi35315. 69 interactors.
DIPiDIP-1256N.
IntActiP39110. 4 interactors.
MINTiMINT-404656.

Structurei

3D structure databases

ProteinModelPortaliP39110.
SMRiP39110.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000163691.
InParanoidiP39110.
KOiK07943.
OMAiQRTLRPF.
OrthoDBiEOG092C508L.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P39110-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLSIIRKQ KLRDKEIRCL ILGLDNSGKS TIVNKLLPKD EQNNDGIMPT
60 70 80 90 100
VGFQIHSLMI KDVTISLWDI GGQRTLRPFW DNYFDKTQAM IWCIDVSLSM
110 120 130 140 150
RFDETLQELK ELINRDENRI GYECAVIVVL NKIDLVEDKS ELHRRCLLVE
160 170 180 190
SELKCLFKPD IRIELVKCSG VTGEGIDNLR DRLVESCHFT Q
Length:191
Mass (Da):22,067
Last modified:February 1, 1995 - v1
Checksum:iCF30AF932A2D2566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36669 Genomic DNA. Translation: AAA50350.1.
X77086 Genomic DNA. Translation: CAA54358.1.
Z47071 Genomic DNA. Translation: CAA87352.1.
AY558409 Genomic DNA. Translation: AAS56735.1.
BK006946 Genomic DNA. Translation: DAA10035.1.
PIRiS51496.
RefSeqiNP_013858.1. NM_001182640.1.

Genome annotation databases

EnsemblFungiiYMR138W; YMR138W; YMR138W.
GeneIDi855169.
KEGGisce:YMR138W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36669 Genomic DNA. Translation: AAA50350.1.
X77086 Genomic DNA. Translation: CAA54358.1.
Z47071 Genomic DNA. Translation: CAA87352.1.
AY558409 Genomic DNA. Translation: AAS56735.1.
BK006946 Genomic DNA. Translation: DAA10035.1.
PIRiS51496.
RefSeqiNP_013858.1. NM_001182640.1.

3D structure databases

ProteinModelPortaliP39110.
SMRiP39110.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35315. 69 interactors.
DIPiDIP-1256N.
IntActiP39110. 4 interactors.
MINTiMINT-404656.

Proteomic databases

MaxQBiP39110.
PRIDEiP39110.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR138W; YMR138W; YMR138W.
GeneIDi855169.
KEGGisce:YMR138W.

Organism-specific databases

EuPathDBiFungiDB:YMR138W.
SGDiS000004746. CIN4.

Phylogenomic databases

HOGENOMiHOG000163691.
InParanoidiP39110.
KOiK07943.
OMAiQRTLRPF.
OrthoDBiEOG092C508L.

Enzyme and pathway databases

BioCyciYEAST:G3O-32831-MONOMER.

Miscellaneous databases

PROiP39110.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCIN4_YEAST
AccessioniPrimary (citable) accession number: P39110
Secondary accession number(s): D6VZW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 30, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 468 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.