Reviewed, UniProtKB/Swiss-Prot P39005 (KRE9_YEAST)

Names and origin

Protein names

Recommended name:
    Cell wall synthesis protein KRE9

Gene names

Name:	KRE9
Ordered Locus Names:	YJL174W
ORF Names:	J0504

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in cell wall beta(1->6) glucan synthesis. Ref.1
Subcellular location	Secreted › cell wall Probable.
Post-translational modification	O-glycosylated.
Sequence similarities	Belongs to the KRE9/KNH1 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell wall Secreted
Domain	Signal
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	1,6-beta-glucan metabolic process Ref.1 Inferred from mutant phenotype. Source: SGD cell wall biogenesis Inferred from electronic annotation. Source: InterPro fungal-type cell wall organization Ref.1 Inferred from mutant phenotype. Source: SGD
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Ref.1 Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ECM13	P38195	1	EBI-9930,EBI-21230
ISU1	Q03020	1	EBI-9930,EBI-29901
MMS22	Q06164	1	EBI-9930,EBI-31156
PCT1	P13259	1	EBI-9930,EBI-5254
PNT1	P38969	1	EBI-9930,EBI-13614
RVB1	Q03940	1	EBI-9930,EBI-30712
YNG2	P38806	1	EBI-9930,EBI-24622

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 276	255	Cell wall synthesis protein KRE9		PRO_0000016849

Sequences

	Sequence		Length	Mass (Da)
	P39005-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 0427F2432E18D93F	FASTA	276	29,989
	10 20 30 40 50 60 MRLQRNSIIC ALVFLVSFVL GDVNIVSPSS KATFSPSGGT VSVPVEWMDN GAYPSLSKIS 70 80 90 100 110 120 TFTFSLCTGP NNNIDCVAVL ASKITPSELT QDDKVYSYTA EFASTLTGNG QYYIQVFAQV 130 140 150 160 170 180 DGQGYTIHYT PRFQLTSMGG VTAYTYSATT EPTPQTSIQT TTTNNAQATT IDSRSFTVPY 190 200 210 220 230 240 TKQTGTSRFA PMQMQPNTKV TATTWTRKFA TSAVTYYSTF GSLPEQATTI TPGWSYTISS 250 260 270 GVNYATPASM PSDNGGWYKP SKRLSLSARK INMRKV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly." Brown J.L., Bussey H. Mol. Cell. Biol. 13:6346-6356(1993) [PubMed: 8413233] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
[2]	Loehning C., Mueller C., Freidel K., Ciriacy M. Submitted (NOV-1990) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L22517 Genomic DNA. Translation: AAC37363.1. X56792 Genomic DNA. Translation: CAA40111.1. Z49449 Genomic DNA. Translation: CAA89469.1.
PIR	S23891.
RefSeq	NP_012361.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5609N.
IntAct	P39005. 28 interactions.
STRING	P39005.
Genome annotation databases
Ensembl	YJL174W; YJL174W; YJL174W; Saccharomyces cerevisiae. [Genome view]
GeneID	853265.
KEGG	sce:YJL174W.
NMPDR	fig|4932.3.peg.3325.
Organism-specific databases
CYGD	YJL174w.
SGD	S000003710. KRE9.
Phylogenomic databases
eggNOG	fuNOG10725.
HOGENOM	HBG396695.
OMA	KVTATTW.
OrthoDB	EOG9PG7H5.
PhylomeDB	P39005.
Gene expression databases
ArrayExpress	P39005.
Genevestigator	P39005.
GermOnline	YJL174W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR008659. KRE9. [Graphical view]
Pfam	PF05390. KRE9. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	973529.

Entry information

Entry name

KRE9_YEAST

Accession

Primary (citable) accession number: P39005

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	February 9, 2010
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)