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P38956

- SNF11_YEAST

UniProt

P38956 - SNF11_YEAST

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Protein

Transcription regulatory protein SNF11

Gene

SNF11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. positive regulation of transcription from RNA polymerase II promoter Source: SGD
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-29679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription regulatory protein SNF11
Alternative name(s):
SWI/SNF complex component SNF11
Gene namesi
Name:SNF11
Ordered Locus Names:YDR073W
ORF Names:D4411
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IV

Organism-specific databases

CYGDiYDR073w.
SGDiS000002480. SNF11.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. cytosol Source: SGD
  2. nucleus Source: SGD
  3. SWI/SNF complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 169168Transcription regulatory protein SNF11PRO_0000072004Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP38956.
PaxDbiP38956.

Expressioni

Gene expression databases

GenevestigatoriP38956.

Interactioni

Subunit structurei

Component of the SWI/SNF global transcription activator complex. The 1.14 MDa SWI/SNF complex is composed of 11 different subunits: one copy each of SWI1, SNF2/SWI2, SNF5, SNF12/SWP73, ARP7/SWP61, ARP9/SWP59; two copies each of SWI3, SNF6, SNF11, SWP82; and three copies of TAF14/SWP29.

Binary interactionsi

WithEntry#Exp.IntActNotes
SNF2P220823EBI-17560,EBI-17526
SNF6P188885EBI-17560,EBI-17550

Protein-protein interaction databases

BioGridi32128. 66 interactions.
DIPiDIP-1530N.
IntActiP38956. 19 interactions.
MINTiMINT-403957.
STRINGi4932.YDR073W.

Structurei

3D structure databases

ProteinModelPortaliP38956.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati28 – 3141-1
Repeati32 – 3541-2
Repeati36 – 3941-3
Repeati40 – 4341-4
Repeati44 – 4741-5
Repeati48 – 5141-6
Repeati76 – 8052-1
Repeati160 – 16562-2

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 51246 X 4 AA tandem repeats of N-[AT]-[NT]-AAdd
BLAST
Regioni76 – 165902 X 5 AA repeats of L-L-A-R-VAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi93 – 10210Poly-Asn

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG39679.
HOGENOMiHOG000141848.
InParanoidiP38956.
KOiK11774.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38956-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSEIAYSNT NTNTENENRN TGAGVDVNTN ANANANATAN ATANATANAT
60 70 80 90 100
AELNLPTVDE QRQYKVQLLL HINSILLARV IQMNNSLQNN LQNNINNSNN
110 120 130 140 150
NNIIRIQQLI SQFLKRVHAN LQCISQINQG VPSAKPLILT PPQLANQQQP
160
PQDILSKLYL LLARVFEIW
Length:169
Mass (Da):18,667
Last modified:February 1, 1995 - v1
Checksum:iFC626E373C32C2C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46796 Genomic DNA. Translation: CAA86795.1.
Z74369 Genomic DNA. Translation: CAA98891.1.
X82086 Genomic DNA. Translation: CAA57601.1.
X82086 Genomic DNA. Translation: CAA57600.1.
AY557668 Genomic DNA. Translation: AAS55994.1.
BK006938 Genomic DNA. Translation: DAA11919.1.
PIRiS48760.
RefSeqiNP_010358.3. NM_001180381.3.

Genome annotation databases

EnsemblFungiiYDR073W; YDR073W; YDR073W.
GeneIDi851645.
KEGGisce:YDR073W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46796 Genomic DNA. Translation: CAA86795.1 .
Z74369 Genomic DNA. Translation: CAA98891.1 .
X82086 Genomic DNA. Translation: CAA57601.1 .
X82086 Genomic DNA. Translation: CAA57600.1 .
AY557668 Genomic DNA. Translation: AAS55994.1 .
BK006938 Genomic DNA. Translation: DAA11919.1 .
PIRi S48760.
RefSeqi NP_010358.3. NM_001180381.3.

3D structure databases

ProteinModelPortali P38956.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32128. 66 interactions.
DIPi DIP-1530N.
IntActi P38956. 19 interactions.
MINTi MINT-403957.
STRINGi 4932.YDR073W.

Proteomic databases

MaxQBi P38956.
PaxDbi P38956.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YDR073W ; YDR073W ; YDR073W .
GeneIDi 851645.
KEGGi sce:YDR073W.

Organism-specific databases

CYGDi YDR073w.
SGDi S000002480. SNF11.

Phylogenomic databases

eggNOGi NOG39679.
HOGENOMi HOG000141848.
InParanoidi P38956.
KOi K11774.

Enzyme and pathway databases

BioCyci YEAST:G3O-29679-MONOMER.

Miscellaneous databases

NextBioi 969221.

Gene expression databases

Genevestigatori P38956.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "SNF11, a new component of the yeast SNF-SWI complex that interacts with a conserved region of SNF2."
    Treich I., Cairns B.R., de Los Santos T., Brewster E., Carlson M.
    Mol. Cell. Biol. 15:4240-4248(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
  7. "Structural analysis of the yeast SWI/SNF chromatin remodeling complex."
    Smith C.L., Horowitz-Scherer R., Flanagan J.F., Woodcock C.L., Peterson C.L.
    Nat. Struct. Biol. 10:141-145(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING OF THE SWI/SNF COMPLEX, ELECTRON MICROSCOPY OF THE SWI/SNF COMPLEX.

Entry informationi

Entry nameiSNF11_YEAST
AccessioniPrimary (citable) accession number: P38956
Secondary accession number(s): D6VS59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 29, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1030 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3