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Protein

Transcription regulatory protein SNF11

Gene

SNF11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

Miscellaneous

Present with 1030 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • positive regulation of transcription by RNA polymerase II Source: SGD
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-29679-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription regulatory protein SNF11
Alternative name(s):
SWI/SNF complex component SNF11
Gene namesi
Name:SNF11
Ordered Locus Names:YDR073W
ORF Names:D4411
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR073W
SGDiS000002480 SNF11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00000720042 – 169Transcription regulatory protein SNF11Add BLAST168

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP38956
PaxDbiP38956
PRIDEiP38956

PTM databases

iPTMnetiP38956

Interactioni

Subunit structurei

Component of the SWI/SNF global transcription activator complex. The 1.14 MDa SWI/SNF complex is composed of 11 different subunits: one copy each of SWI1, SNF2/SWI2, SNF5, SNF12/SWP73, ARP7/SWP61, ARP9/SWP59; two copies each of SWI3, SNF6, SNF11, SWP82; and three copies of TAF14/SWP29.

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi32128, 145 interactors
DIPiDIP-1530N
IntActiP38956, 24 interactors
MINTiP38956
STRINGi4932.YDR073W

Structurei

3D structure databases

ProteinModelPortaliP38956
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati28 – 311-14
Repeati32 – 351-24
Repeati36 – 391-34
Repeati40 – 431-44
Repeati44 – 471-54
Repeati48 – 511-64
Repeati76 – 802-15
Repeati160 – 1652-26

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni28 – 516 X 4 AA tandem repeats of N-[AT]-[NT]-AAdd BLAST24
Regioni76 – 1652 X 5 AA repeats of L-L-A-R-VAdd BLAST90

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi93 – 102Poly-Asn10

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000141848
InParanoidiP38956
KOiK11774

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38956-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSEIAYSNT NTNTENENRN TGAGVDVNTN ANANANATAN ATANATANAT
60 70 80 90 100
AELNLPTVDE QRQYKVQLLL HINSILLARV IQMNNSLQNN LQNNINNSNN
110 120 130 140 150
NNIIRIQQLI SQFLKRVHAN LQCISQINQG VPSAKPLILT PPQLANQQQP
160
PQDILSKLYL LLARVFEIW
Length:169
Mass (Da):18,667
Last modified:February 1, 1995 - v1
Checksum:iFC626E373C32C2C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46796 Genomic DNA Translation: CAA86795.1
Z74369 Genomic DNA Translation: CAA98891.1
X82086 Genomic DNA Translation: CAA57601.1
X82086 Genomic DNA Translation: CAA57600.1
AY557668 Genomic DNA Translation: AAS55994.1
BK006938 Genomic DNA Translation: DAA11919.1
PIRiS48760
RefSeqiNP_010358.3, NM_001180381.3

Genome annotation databases

EnsemblFungiiYDR073W; YDR073W; YDR073W
GeneIDi851645
KEGGisce:YDR073W

Similar proteinsi

Entry informationi

Entry nameiSNF11_YEAST
AccessioniPrimary (citable) accession number: P38956
Secondary accession number(s): D6VS59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health