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Protein

Major pollen allergen Car b 1 isoform 2

Gene
N/A
Organism
Carpinus betulus (European hornbeam) (Carpinus caucasica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. response to biotic stimulus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Pathogenesis-related protein

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Car b 1 isoform 2
Alternative name(s):
Allergen Car b I
Allergen: Car b 1
OrganismiCarpinus betulus (European hornbeam) (Carpinus caucasica)
Taxonomic identifieri12990 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeCarpinus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei180. Car b 1.
189. Car b 1.0201.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 160159Major pollen allergen Car b 1 isoform 2PRO_0000154186Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP38950.
SMRiP38950. Positions 2-160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38950-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVFNYEAET TSVIPAARLF KAFILDGNKL IPKVSPQAVS SVENVEGNGG
60 70 80 90 100
PGTIKKITFS EGSPVKYVKE RVEEIDHTNF KYNYTVIEGD VLGDKLEKVS
110 120 130 140 150
HELKIVAAPG GGSIVKISSK FHAKGYHEVN AEEMKGAKEM AEKLLRAVES
160
YLLAHTAEYN
Length:160
Mass (Da):17,487
Last modified:January 22, 2007 - v2
Checksum:i8200078865A15C71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X66933 mRNA. Translation: CAA47367.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X66933 mRNA. Translation: CAA47367.1.

3D structure databases

ProteinModelPortaliP38950.
SMRiP38950. Positions 2-160.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei180. Car b 1.
189. Car b 1.0201.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "PCR based cloning and sequencing of isogenes encoding the tree pollen major allergen Car b I from Carpinus betulus, hornbeam."
    Nedergaard Larsen J., Stroeman P., Ipsen H.
    Mol. Immunol. 29:703-711(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Pollen.

Entry informationi

Entry nameiMPAC2_CARBE
AccessioniPrimary (citable) accession number: P38950
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 1995
Last sequence update: January 22, 2007
Last modified: September 30, 2014
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.