P38950 (MPAC2_CARBE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Major pollen allergen Car b 1 isoform 2 Alternative name(s): Allergen Car b I Allergen=Car b 1
Organism	Carpinus betulus (European hornbeam) (Carpinus caucasica)
Taxonomic identifier	12990 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fagales › Betulaceae › Carpinus

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the BetVI family.

Ontologies

Keywords
Biological process	Plant defense
Disease	Allergen
Molecular function	Pathogenesis-related protein
Gene Ontology (GO)
Biological_process	defense response Inferred from electronic annotation. Source: UniProtKB-KW response to biotic stimulus Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 160	159	Major pollen allergen Car b 1 isoform 2		PRO_0000154186

Sequences

	Sequence		Length	Mass (Da)
	P38950 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 8200078865A15C71	FASTA	160	17,487
	10 20 30 40 50 60 MGVFNYEAET TSVIPAARLF KAFILDGNKL IPKVSPQAVS SVENVEGNGG PGTIKKITFS 70 80 90 100 110 120 EGSPVKYVKE RVEEIDHTNF KYNYTVIEGD VLGDKLEKVS HELKIVAAPG GGSIVKISSK 130 140 150 160 FHAKGYHEVN AEEMKGAKEM AEKLLRAVES YLLAHTAEYN

References

[1]	"PCR based cloning and sequencing of isogenes encoding the tree pollen major allergen Car b I from Carpinus betulus, hornbeam." Nedergaard Larsen J., Stroeman P., Ipsen H. Mol. Immunol. 29:703-711(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Pollen.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X66933 mRNA. Translation: CAA47367.1.
3D structure databases
ProteinModelPortal	P38950.
SMR	P38950. Positions 2-160.
ModBase	Search...
Protein family/group databases
Allergome	180. Car b 1. 189. Car b 1.0201.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.30.530.20. 1 hit.
InterPro	IPR024949. Bet_v_I_allergen. IPR000916. Bet_v_I_dom. IPR023393. START-like_dom. [Graphical view]
Pfam	PF00407. Bet_v_1. 1 hit. [Graphical view]
PRINTS	PR00634. BETALLERGEN.
PROSITE	PS00451. PATHOGENESIS_BETVI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MPAC2_CARBE

Accession

Primary (citable) accession number: P38950

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program