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Protein

Major pollen allergen Car b 1 isoforms 1A and 1B

Gene
N/A
Organism
Carpinus betulus (European hornbeam) (Carpinus caucasica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

The sequence shown is that of isoform 1A.

GO - Biological processi

Keywordsi

Molecular functionPathogenesis-related protein
Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Car b 1 isoforms 1A and 1B
Alternative name(s):
Allergen Car b I
Allergen: Car b 1
OrganismiCarpinus betulus (European hornbeam) (Carpinus caucasica)
Taxonomic identifieri12990 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeCarpinus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei180. Car b 1.
181. Car b 1.0101.
182. Car b 1.0102.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001541852 – 160Major pollen allergen Car b 1 isoforms 1A and 1BAdd BLAST159

Structurei

3D structure databases

ProteinModelPortaliP38949.
SMRiP38949.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiView protein in InterPro
IPR000916. Bet_v_I/MLP.
IPR024949. Bet_v_I_allergen.
IPR023393. START-like_dom_sf.
PfamiView protein in Pfam
PF00407. Bet_v_1. 1 hit.
PRINTSiPR00634. BETALLERGEN.
SMARTiView protein in SMART
SM01037. Bet_v_1. 1 hit.
PROSITEiView protein in PROSITE
PS00451. PATHOGENESIS_BETVI. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38949-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVFNYEAET PSVIPAARLF KSYVLDGDKL IPKVAPQVIS SVENVGGNGG
60 70 80 90 100
PGTIKNITFA EGIPFKFVKE RVDEVDNANF KYNYTVIEGD VLGDKLEKVS
110 120 130 140 150
HELKIVAAPG GGSIVKISSK FHAKGYHEVN AEKMKGAKEM AEKLLRAVES
160
YLLAHTAEYN
Length:160
Mass (Da):17,402
Last modified:January 23, 2007 - v2
Checksum:iDE891173C8E587AE
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti38V → A in isoform 1B. 1
Natural varianti63I → S in isoform 1B. 1
Natural varianti133K → E in isoform 1B. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X66932 mRNA. Translation: CAA47366.1.
X66918 mRNA. Translation: CAA47357.1.

Similar proteinsi

Entry informationi

Entry nameiMPAC1_CARBE
AccessioniPrimary (citable) accession number: P38949
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families