P38946 (CAT1_CLOK5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Succinyl-CoA:coenzyme A transferase
EC=2.8.3.-

Gene names

Name:	cat1
Ordered Locus Names:	CKL_3016

Organism

Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) [Complete proteome] [HAMAP]

Taxonomic identifier

431943 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium kluyveri

Protein attributes

Sequence length	538 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Forms succinyl-CoA from succinate and acetyl-CoA.
Induction	Efficiently transcribed only during growth on ethanol plus succinate.
Sequence similarities	Belongs to the acetyl-CoA hydrolase/transferase family.

Ontologies

Keywords
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	acetyl-CoA metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 538	538	Succinyl-CoA:coenzyme A transferase		PRO_0000215525

Sequences

	Sequence		Length	Mass (Da)
	P38946 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: D595BAACD087B484	FASTA	538	58,853
	10 20 30 40 50 60 MSKGIKNSQL KKKNVKASNV AEKIEEKVEK TDKVVEKAAE VTEKRIRNLK LQEKVVTADV 70 80 90 100 110 120 AADMIENGMI VAISGFTPSG YPKEVPKALT KKVNALEEEF KVTLYTGSST GADIDGEWAK 130 140 150 160 170 180 AGIIERRIPY QTNSDMRKKI NDGSIKYADM HLSHMAQYIN YSVIPKVDIA IIEAVAITEE 190 200 210 220 230 240 GDIIPSTGIG NTATFVENAD KVIVEINEAQ PLELEGMADI YTLKNPPRRE PIPIVNAGNR 250 260 270 280 290 300 IGTTYVTCGS EKICAIVMTN TQDKTRPLTE VSPVSQAISD NLIGFLNKEV EEGKLPKNLL 310 320 330 340 350 360 PIQSGVGSVA NAVLAGLCES NFKNLSCYTE VIQDSMLKLI KCGKADVVSG TSISPSPEML 370 380 390 400 410 420 PEFIKDINFF REKIVLRPQE ISNNPEIARR IGVISINTAL EVDIYGNVNS THVMGSKMMN 430 440 450 460 470 480 GIGGSGDFAR NAYLTIFTTE SIAKKGDISS IVPMVSHVDH TEHDVMVIVT EQGVADLRGL 490 500 510 520 530 SPREKAVAII ENCVHPDYKD MLMEYFEEAC KSSGGNTPHN LEKALSWHTK FIKTGSMK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular analysis of the anaerobic succinate degradation pathway in Clostridium kluyveri." Soehling B., Gottschalk G. J. Bacteriol. 178:871-880(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features." Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H., Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F., Hagemeier C., Thauer R.K., Gottschalk G. Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8527 / DSM 555 / NCIMB 10680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L21902 Genomic DNA. Translation: AAA92346.1. CP000673 Genomic DNA. Translation: EDK35024.1.
RefSeq	YP_001396395.1. NC_009706.1.
3D structure databases
ProteinModelPortal	P38946.
SMR	P38946. Positions 44-538.
ModBase	Search...
Protein-protein interaction databases
STRING	431943.CKL_3016.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EDK35024; EDK35024; CKL_3016.
GeneID	5392695.
KEGG	ckl:CKL_3016.
PATRIC	19467580. VBICloKlu111549_3120.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0427.
HOGENOM	HOG000172597.
KO	K01067.
OMA	GVWTGAS.
ProtClustDB	CLSK869356.
Enzyme and pathway databases
BioCyc	CKLU431943:GJF1-3009-MONOMER. MetaCyc:MONOMER-13465.
Family and domain databases
InterPro	IPR026888. AcetylCoA_hyd_C. IPR003702. ActCoA_hydro. IPR017821. Succinate_CoA_transferase. [Graphical view]
PANTHER	PTHR21432. PTHR21432. 1 hit. PTHR21432:SF10. PTHR21432:SF10. 1 hit.
Pfam	PF13336. AcetylCoA_hyd_C. 1 hit. PF02550. AcetylCoA_hydro. 1 hit. [Graphical view]
TIGRFAMs	TIGR03458. YgfH_subfam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CAT1_CLOK5

Accession

Primary (citable) accession number: P38946
Secondary accession number(s): A5N1M8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program