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Protein

Casein kinase II subunit beta'

Gene

CKB2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a complex role in regulating the basal catalytic activity of the alpha subunit.By similarity

Miscellaneous

Present with 7160 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • protein kinase regulator activity Source: SGD
  • protein serine/threonine kinase inhibitor activity Source: SGD

GO - Biological processi

  • cellular response to DNA damage stimulus Source: SGD
  • peptidyl-serine phosphorylation Source: SGD
  • peptidyl-threonine phosphorylation Source: SGD
  • protein phosphorylation Source: SGD
  • regulation of transcription by RNA polymerase I Source: SGD
  • regulation of transcription by RNA polymerase III Source: SGD
  • rRNA methylation Source: Reactome

Enzyme and pathway databases

BioCyciYEAST:G3O-33585-MONOMER
ReactomeiR-SCE-2514853 Condensation of Prometaphase Chromosomes
R-SCE-6798695 Neutrophil degranulation
R-SCE-6804756 Regulation of TP53 Activity through Phosphorylation

Names & Taxonomyi

Protein namesi
Recommended name:
Casein kinase II subunit beta'
Short name:
CK II beta'
Gene namesi
Name:CKB2
Ordered Locus Names:YOR039W
ORF Names:OR26.32
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR039W
SGDiS000005565 CKB2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000682581 – 258Casein kinase II subunit beta'Add BLAST258

Post-translational modificationi

Phosphorylated by alpha subunit.By similarity
The N-terminus is blocked.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP38930
PaxDbiP38930
PRIDEiP38930

PTM databases

iPTMnetiP38930

Interactioni

Subunit structurei

Tetramer composed of an alpha subunit, an alpha' subunit, one beta subunit and one beta' subunit. Interacts with FACT subunits POB3 and SPT16.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi34441, 489 interactors
DIPiDIP-262N
IntActiP38930, 46 interactors
MINTiP38930
STRINGi4932.YOR039W

Structurei

3D structure databases

ProteinModelPortaliP38930
SMRiP38930
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000003781
HOGENOMiHOG000039270
KOiK03115
OMAiCPRVLCQ
OrthoDBiEOG092C4DSU

Family and domain databases

Gene3Di1.10.1820.10, 1 hit
InterProiView protein in InterPro
IPR016149 Casein_kin_II_reg-sub_N
IPR035991 Casein_kinase_II_beta_like
IPR000704 Casein_kinase_II_reg-sub
PANTHERiPTHR11740 PTHR11740, 1 hit
PfamiView protein in Pfam
PF01214 CK_II_beta, 1 hit
PRINTSiPR00472 CASNKINASEII
SMARTiView protein in SMART
SM01085 CK_II_beta, 1 hit
SUPFAMiSSF57798 SSF57798, 1 hit
PROSITEiView protein in PROSITE
PS01101 CK2_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

P38930-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRSENVGT VTREGSRVEQ DDVLMDDDSD SSEYVDMWID LFLGRKGHEY
60 70 80 90 100
FCDVDPEYIT DRFNLMNLQK TVSKFSYVVQ YIVDDLDDSI LENMTHARLE
110 120 130 140 150
QLESDSRKLY GLIHARYIIT IKGLQKMYAK YKEADFGRCP RVYCNLQQLL
160 170 180 190 200
PVGLHDIPGI DCVKLYCPSC EDLYIPKSSR HSSIDGAYFG TSFPGMFLQA
210 220 230 240 250
FPDMVPKHPT KRYVPKIFGF ELHKQAQLTR WQELQRLKLV EKLESKDVDL

TKSGGFKT
Length:258
Mass (Da):29,842
Last modified:February 1, 1995 - v1
Checksum:iD6060CB3D70B19A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08849 Genomic DNA Translation: AAA21656.1
X87331 Genomic DNA Translation: CAA60758.1
Z74947 Genomic DNA Translation: CAA99229.1
AY692981 Genomic DNA Translation: AAT93000.1
X82893 Genomic DNA Translation: CAA58064.1
BK006948 Genomic DNA Translation: DAA10822.1
PIRiA54907
RefSeqiNP_014682.1, NM_001183458.1

Genome annotation databases

EnsemblFungiiYOR039W; YOR039W; YOR039W
GeneIDi854204
KEGGisce:YOR039W

Similar proteinsi

Entry informationi

Entry nameiCSK2C_YEAST
AccessioniPrimary (citable) accession number: P38930
Secondary accession number(s): D6W2A6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 163 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

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