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Protein

Putative mitochondrial carrier protein PET8

Gene

PET8

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • S-adenosyl-L-methionine transmembrane transporter activity Source: SGD

GO - Biological processi

  • S-adenosyl-L-methionine transmembrane transport Source: GOC
  • S-adenosyl-L-methionine transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-33045-MONOMER.

Protein family/group databases

TCDBi2.A.29.18.1. the mitochondrial carrier (mc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative mitochondrial carrier protein PET8
Gene namesi
Name:PET8
Ordered Locus Names:YNL003C
ORF Names:N2012
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL003C.
SGDiS000004948. PET8.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei50 – 7021Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei98 – 11821Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei153 – 16917Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei194 – 21421Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei252 – 27221Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: SGD
  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Putative mitochondrial carrier protein PET8PRO_0000090686Add
BLAST

Proteomic databases

MaxQBiP38921.
PeptideAtlasiP38921.

Interactioni

Protein-protein interaction databases

BioGridi35822. 127 interactions.
DIPiDIP-2944N.
IntActiP38921. 2 interactions.
MINTiMINT-1585704.

Structurei

3D structure databases

ProteinModelPortaliP38921.
SMRiP38921. Positions 6-278.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati2 – 7574Solcar 1Add
BLAST
Repeati92 – 17887Solcar 2Add
BLAST
Repeati192 – 27180Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000074950.
HOGENOMiHOG000038810.
InParanoidiP38921.
KOiK15111.
OMAiGWSTTIM.
OrthoDBiEOG7008K4.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTFFLSLLS GAAAGTSTDL VFFPIDTIKT RLQAKGGFFA NGGYKGIYRG
60 70 80 90 100
LGSAVVASAP GASLFFISYD YMKVKSRPYI SKLYSQGSEQ LIDTTTHMLS
110 120 130 140 150
SSIGEICACL VRVPAEVVKQ RTQVHSTNSS WQTLQSILRN DNKEGLRKNL
160 170 180 190 200
YRGWSTTIMR EIPFTCIQFP LYEYLKKTWA KANGQSQVEP WKGAICGSIA
210 220 230 240 250
GGIAAATTTP LDFLKTRLML NKTTASLGSV IIRIYREEGP AVFFSGVGPR
260 270 280
TMWISAGGAI FLGMYETVHS LLSKSFPTAG EMRA
Length:284
Mass (Da):31,027
Last modified:February 1, 1995 - v1
Checksum:i761378D67DAFD343
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02536 Genomic DNA. Translation: AAA64802.1.
X77114 Genomic DNA. Translation: CAA54377.1.
Z71279 Genomic DNA. Translation: CAA95862.1.
BK006947 Genomic DNA. Translation: DAA10540.1.
PIRiS45458.
RefSeqiNP_014395.3. NM_001182842.3.

Genome annotation databases

EnsemblFungiiYNL003C; YNL003C; YNL003C.
GeneIDi855729.
KEGGisce:YNL003C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02536 Genomic DNA. Translation: AAA64802.1.
X77114 Genomic DNA. Translation: CAA54377.1.
Z71279 Genomic DNA. Translation: CAA95862.1.
BK006947 Genomic DNA. Translation: DAA10540.1.
PIRiS45458.
RefSeqiNP_014395.3. NM_001182842.3.

3D structure databases

ProteinModelPortaliP38921.
SMRiP38921. Positions 6-278.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35822. 127 interactions.
DIPiDIP-2944N.
IntActiP38921. 2 interactions.
MINTiMINT-1585704.

Protein family/group databases

TCDBi2.A.29.18.1. the mitochondrial carrier (mc) family.

Proteomic databases

MaxQBiP38921.
PeptideAtlasiP38921.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL003C; YNL003C; YNL003C.
GeneIDi855729.
KEGGisce:YNL003C.

Organism-specific databases

EuPathDBiFungiDB:YNL003C.
SGDiS000004948. PET8.

Phylogenomic databases

GeneTreeiENSGT00550000074950.
HOGENOMiHOG000038810.
InParanoidiP38921.
KOiK15111.
OMAiGWSTTIM.
OrthoDBiEOG7008K4.

Enzyme and pathway databases

BioCyciYEAST:G3O-33045-MONOMER.

Miscellaneous databases

NextBioi980108.
PROiP38921.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Two yeast chromosomes are related by a fossil duplication of their centromeric regions."
    Lalo D., Stettler S., Mariotte S., Slonimski P.P., Thuriaux P.
    C. R. Acad. Sci. III, Sci. Vie 316:367-373(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Organization of the centromeric region of chromosome XIV in Saccharomyces cerevisiae."
    Lalo D., Stettler S., Mariotte S., Gendreau E., Thuriaux P.
    Yeast 10:523-533(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  3. "Nucleotide sequence analysis of an 8887 bp region of the left arm of yeast chromosome XIV, encompassing the centromere sequence."
    Verhasselt P., Aert R., Voet M., Volckaert G.
    Yeast 10:945-951(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  4. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiPET8_YEAST
AccessioniPrimary (citable) accession number: P38921
Secondary accession number(s): D6W1H4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 11, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 521 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.