RPB11

Functionⁱ

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft. Seems to be involved transcript termination.1 Publication

Miscellaneous

Present with 4280 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functionⁱ

DNA binding Source: InterPro
protein dimerization activity Source: InterPro
RNA polymerase II activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

termination of RNA polymerase II transcription
Source: SGD
Inferred from mutant phenotypeⁱ
- 16537912
transcription, RNA-templated Source: GOC
transcription by RNA polymerase II
Source: SGD
Inferred from mutant phenotypeⁱ
- 17179178

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Transcription

Biological process

Transcription

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-33422-MONOMER.
Reactomeⁱ	R-SCE-113418. Formation of the Early Elongation Complex. R-SCE-674695. RNA Polymerase II Pre-transcription Events. R-SCE-6781823. Formation of TC-NER Pre-Incision Complex. R-SCE-6782135. Dual incision in TC-NER. R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER. R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes. R-SCE-72086. mRNA Capping. R-SCE-72165. mRNA Splicing - Minor Pathway. R-SCE-73776. RNA Polymerase II Promoter Escape. R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening. R-SCE-75953. RNA Polymerase II Transcription Initiation. R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance. R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

BioCycⁱ

YEAST:G3O-33422-MONOMER.

Reactomeⁱ

R-SCE-113418. Formation of the Early Elongation Complex.
R-SCE-674695. RNA Polymerase II Pre-transcription Events.
R-SCE-6781823. Formation of TC-NER Pre-Incision Complex.
R-SCE-6782135. Dual incision in TC-NER.
R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes.
R-SCE-72086. mRNA Capping.
R-SCE-72165. mRNA Splicing - Minor Pathway.
R-SCE-73776. RNA Polymerase II Promoter Escape.
R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-SCE-75953. RNA Polymerase II Transcription Initiation.
R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: DNA-directed RNA polymerase II subunit RPB11 Short name: RNA polymerase II subunit B11 Alternative name(s): B13.6 DNA-directed RNA polymerase II 13.6 kDa polypeptide
Gene namesⁱ	Name:RPB11 Ordered Locus Names:YOL005C
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome XV

Organism-specific databases

EuPathDBⁱ	FungiDB:YOL005C.
Saccharomyces Genome Database More...SGDⁱ	S000005365. RPB11.

Keywords - Cellular componentⁱ

DNA-directed RNA polymerase, Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	108	E → G or V: Transcript termination readthrough. 1 Publication	1
Mutagenesisⁱ	108	E → K: Transcript termination readthrough. Lethal. 1 Publication	1
Mutagenesisⁱ	111	L → P: Transcript termination readthrough. 1 Publication	1
Mutagenesisⁱ	114	L → P: Transcript termination readthrough. 1 Publication	1

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000149315	1 – 120	DNA-directed RNA polymerase II subunit RPB11Add BLAST		120

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P38902.
PaxDbⁱ	P38902.
PRIDEⁱ	P38902.

Interactionⁱ

Subunit structureⁱ

Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.3 Publications

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
DST1	P07273	2	EBI-15806,EBI-19168
IWR1	Q07532	5	EBI-15806,EBI-33428
RPB10	P22139	3	EBI-15806,EBI-15802
RPB2	P08518	10	EBI-15806,EBI-15767
RPB3	P16370	12	EBI-15806,EBI-15773
RPB4	P20433	2	EBI-15806,EBI-15777
RPB5	P20434	27	EBI-15806,EBI-15781
RPB7	P34087	2	EBI-15806,EBI-15790
RPB8	P20436	3	EBI-15806,EBI-15794
RPB9	P27999	7	EBI-15806,EBI-15798
RPO21	P04050	9	EBI-15806,EBI-15760
RPO26	P20435	2	EBI-15806,EBI-15786
SPT5	P27692	5	EBI-15806,EBI-17937
TFG1	P41895	5	EBI-15806,EBI-18912
TFG2	P41896	6	EBI-15806,EBI-18916

Show more details

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	34399. 387 interactors.
Database of interacting proteins More...DIPⁱ	DIP-937N.
IntActⁱ	P38902. 34 interactors.
Molecular INTeraction database More...MINTⁱ	P38902.
STRINGⁱ	4932.YOL005C.

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Show more details

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	7 – 9	Combined sources	3
Beta strandⁱ	18 – 20	Combined sources	3
Beta strandⁱ	21 – 23	Combined sources	3
Beta strandⁱ	25 – 27	Combined sources	3
Beta strandⁱ	30 – 37	Combined sources	8
Helixⁱ	40 – 50	Combined sources	11
Beta strandⁱ	56 – 62	Combined sources	7
Beta strandⁱ	66 – 68	Combined sources	3
Beta strandⁱ	70 – 77	Combined sources	8
Helixⁱ	83 – 108	Combined sources	26
Turnⁱ	109 – 111	Combined sources	3

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1I3Q	X-ray	3.10	K	1-120	[»]
	1I50	X-ray	2.80	K	1-120	[»]
	1I6H	X-ray	3.30	K	1-120	[»]
	1K83	X-ray	2.80	K	1-120	[»]
	1NIK	X-ray	4.10	K	1-120	[»]
	1NT9	X-ray	4.20	K	1-120	[»]
	1PQV	X-ray	3.80	K	1-120	[»]
	1R5U	X-ray	4.50	K	1-120	[»]
	1R9S	X-ray	4.25	K	1-120	[»]
	1R9T	X-ray	3.50	K	1-120	[»]
	1SFO	X-ray	3.61	K	1-120	[»]
	1TWA	X-ray	3.20	K	1-120	[»]
	1TWC	X-ray	3.00	K	1-120	[»]
	1TWF	X-ray	2.30	K	1-120	[»]
	1TWG	X-ray	3.30	K	1-120	[»]
	1TWH	X-ray	3.40	K	1-120	[»]
	1WCM	X-ray	3.80	K	1-120	[»]
	1Y1V	X-ray	3.80	K	1-120	[»]
	1Y1W	X-ray	4.00	K	1-120	[»]
	1Y1Y	X-ray	4.00	K	1-120	[»]
	1Y77	X-ray	4.50	K	1-120	[»]
	2B63	X-ray	3.80	K	1-120	[»]
	2B8K	X-ray	4.15	K	1-120	[»]
	2E2H	X-ray	3.95	K	1-120	[»]
	2E2I	X-ray	3.41	K	1-120	[»]
	2E2J	X-ray	3.50	K	1-120	[»]
	2JA5	X-ray	3.80	K	1-120	[»]
	2JA6	X-ray	4.00	K	1-120	[»]
	2JA7	X-ray	3.80	K/W	1-120	[»]
	2JA8	X-ray	3.80	K	1-120	[»]
	2NVQ	X-ray	2.90	K	1-120	[»]
	2NVT	X-ray	3.36	K	1-120	[»]
	2NVX	X-ray	3.60	K	1-120	[»]
	2NVY	X-ray	3.40	K	1-120	[»]
	2NVZ	X-ray	4.30	K	1-120	[»]
	2R7Z	X-ray	3.80	K	1-120	[»]
	2R92	X-ray	3.80	K	1-120	[»]
	2R93	X-ray	4.00	K	1-120	[»]
	2VUM	X-ray	3.40	K	1-120	[»]
	2YU9	X-ray	3.40	K	1-120	[»]
	3CQZ	X-ray	2.80	K	1-120	[»]
	3FKI	X-ray	3.88	K	1-120	[»]
	3GTG	X-ray	3.78	K	1-120	[»]
	3GTJ	X-ray	3.42	K	1-120	[»]
	3GTK	X-ray	3.80	K	1-120	[»]
	3GTL	X-ray	3.38	K	1-120	[»]
	3GTM	X-ray	3.80	K	1-120	[»]
	3GTO	X-ray	4.00	K	1-120	[»]
	3GTP	X-ray	3.90	K	1-120	[»]
	3GTQ	X-ray	3.80	K	1-120	[»]
	3H3V	X-ray	4.00	L	1-120	[»]
	3HOU	X-ray	3.20	K/W	1-120	[»]
	3HOV	X-ray	3.50	K	1-120	[»]
	3HOW	X-ray	3.60	K	1-120	[»]
	3HOX	X-ray	3.65	K	1-120	[»]
	3HOY	X-ray	3.40	K	1-120	[»]
	3HOZ	X-ray	3.65	K	1-120	[»]
	3I4M	X-ray	3.70	K	1-120	[»]
	3I4N	X-ray	3.90	K	1-120	[»]
	3J0K	electron microscopy	36.00	K	1-120	[»]
	3J1N	electron microscopy	16.00	K	1-120	[»]
	3K1F	X-ray	4.30	K	1-120	[»]
	3K7A	X-ray	3.80	K	1-120	[»]
3M3Y	X-ray	3.18	K	1-120	[»]
3M4O	X-ray	3.57	K	1-120	[»]
3PO2	X-ray	3.30	K	1-120	[»]
3PO3	X-ray	3.30	K	1-120	[»]
3QT1	X-ray	4.30	K	1-120	[»]
3RZD	X-ray	3.30	K	1-120	[»]
3RZO	X-ray	3.00	K	1-120	[»]
3S14	X-ray	2.85	K	1-120	[»]
3S15	X-ray	3.30	K	1-120	[»]
3S16	X-ray	3.24	K	1-120	[»]
3S17	X-ray	3.20	K	1-120	[»]
3S1M	X-ray	3.13	K	1-120	[»]
3S1N	X-ray	3.10	K	1-120	[»]
3S1Q	X-ray	3.30	K	1-120	[»]
3S1R	X-ray	3.20	K	1-120	[»]
3S2D	X-ray	3.20	K	1-120	[»]
3S2H	X-ray	3.30	K	1-120	[»]
4A3B	X-ray	3.50	K	1-120	[»]
4A3C	X-ray	3.50	K	1-120	[»]
4A3D	X-ray	3.40	K	1-120	[»]
4A3E	X-ray	3.40	K	1-120	[»]
4A3F	X-ray	3.50	K	1-120	[»]
4A3G	X-ray	3.50	K	1-120	[»]
4A3I	X-ray	3.80	K	1-120	[»]
4A3J	X-ray	3.70	K	1-120	[»]
4A3K	X-ray	3.50	K	1-120	[»]
4A3L	X-ray	3.50	K	1-120	[»]
4A3M	X-ray	3.90	K	1-120	[»]
4A93	X-ray	3.40	K	1-120	[»]
4BBR	X-ray	3.40	K	1-120	[»]
4BBS	X-ray	3.60	K	1-120	[»]
4BXX	X-ray	3.28	K	1-120	[»]
4BXZ	X-ray	4.80	K	1-120	[»]
4BY1	X-ray	3.60	K	1-120	[»]
4BY7	X-ray	3.15	K	1-120	[»]
4V1M	electron microscopy	6.60	K	1-120	[»]
4V1N	electron microscopy	7.80	K	1-120	[»]
4V1O	electron microscopy	9.70	K	1-120	[»]
4X67	X-ray	4.10	K	1-120	[»]
4X6A	X-ray	3.96	K	1-120	[»]
4Y52	X-ray	3.50	K	1-120	[»]
4Y7N	X-ray	3.30	K	1-120	[»]
5C3E	X-ray	3.70	K	1-120	[»]
5C44	X-ray	3.95	K	1-120	[»]
5C4A	X-ray	4.20	K	1-120	[»]
5C4J	X-ray	4.00	K	1-120	[»]
5C4X	X-ray	4.00	K	1-120	[»]
5FMF	electron microscopy	6.00	K	1-115	[»]
5FYW	electron microscopy	4.35	K	1-120	[»]
5FZ5	electron microscopy	8.80	K	1-120	[»]
5IP7	X-ray	3.52	K	1-115	[»]
5IP9	X-ray	3.90	K	1-115	[»]
5OT2	X-ray	3.20	K	1-120	[»]
5SVA	electron microscopy	15.30	K	1-120	[»]
5U5Q	X-ray	3.80	K	1-120	[»]
5VVR	electron microscopy	5.80	K	1-120	[»]
5VVS	electron microscopy	6.40	K	1-120	[»]
ProteinModelPortalⁱ	P38902.
SMRⁱ	P38902.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ

P38902.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.Curated

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074975.
HOGENOMⁱ	HOG000179862.
InParanoidⁱ	P38902.
KEGG Orthology (KO) More...KOⁱ	K03008.
OMAⁱ	MAGYKIA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C5QHE.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06926. RNAP_II_RPB11. 1 hit.
Gene3Dⁱ	3.30.1360.10. 1 hit.
InterProⁱ	View protein in InterPro IPR037685. RBP11. IPR036603. RBP11-like. IPR009025. RBP11-like_dimer. IPR008193. RNA_pol_Rpb11_13-16kDa_CS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13656. RNA_pol_L_2. 1 hit.
SUPFAMⁱ	SSF55257. SSF55257. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01154. RNA_POL_L_13KD. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

P38902-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNAPDRFELF LLGEGESKLK IDPDTKAPNA VVITFEKEDH TLGNLIRAEL 
        60         70         80         90        100
LNDRKVLFAA YKVEHPFFAR FKLRIQTTEG YDPKDALKNA CNSIINKLGA 
       110        120
LKTNFETEWN LQTLAADDAF

Length:120

Mass (Da):13,616

Last modified:February 1, 1995 - v1

Checksum:ⁱA98D109C5FF8E356

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	S62624 Genomic DNA. Translation: AAB27135.1. Z74747 Genomic DNA. Translation: CAA99004.1. AY557998 Genomic DNA. Translation: AAS56324.1. BK006948 Genomic DNA. Translation: DAA10778.1.
PIRⁱ	S58933.
NCBI Reference Sequences More...RefSeqⁱ	NP_014638.1. NM_001183259.1.

Genome annotation databases

EnsemblFungiⁱ	YOL005C; YOL005C; YOL005C.
GeneIDⁱ	854157.
KEGGⁱ	sce:YOL005C.

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P38902	C7GJV7 G2WMM6 A6ZNK1 E7QKJ6 E7KHS4 H0GNB1 A0A0L8VHM0 E7NNA8 N1P2V7 E7Q959 +4	Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's yeast) Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) Saccharomyces cerevisiae (strain Zymaflore VL3) (Baker's yeast) Saccharomyces cerevisiae (strain AWRI796) (Baker's yeast) Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) (Yeast) Saccharomyces sp. 'boulardii' Saccharomyces cerevisiae (strain FostersO) (Baker's yeast) Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) Saccharomyces cerevisiae (strain FostersB) (Baker's yeast) And more	120	UniRef100_P38902	Cluster: DNA-directed RNA polymerase II subunit RPB11	15

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P38902	C7GJV7 G2WMM6 A6ZNK1 E7QKJ6 E7KHS4 H0GNB1 A0A0L8VHM0 E7NNA8 N1P2V7 E7Q959 +12	Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's yeast) Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) Saccharomyces cerevisiae (strain Zymaflore VL3) (Baker's yeast) Saccharomyces cerevisiae (strain AWRI796) (Baker's yeast) Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) (Yeast) Saccharomyces sp. 'boulardii' Saccharomyces cerevisiae (strain FostersO) (Baker's yeast) Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) Saccharomyces cerevisiae (strain FostersB) (Baker's yeast) And more	120	UniRef90_P38902	Cluster: DNA-directed RNA polymerase II subunit RPB11	23

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P38902	C7GJV7 G2WMM6 A6ZNK1 E7QKJ6 E7KHS4 H0GNB1 A0A0L8VHM0 E7NNA8 N1P2V7 E7Q959 +54	Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's yeast) Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) Saccharomyces cerevisiae (strain Zymaflore VL3) (Baker's yeast) Saccharomyces cerevisiae (strain AWRI796) (Baker's yeast) Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) (Yeast) Saccharomyces sp. 'boulardii' Saccharomyces cerevisiae (strain FostersO) (Baker's yeast) Saccharomyces cerevisiae (strain CEN.PK113-7D) (Baker's yeast) Saccharomyces cerevisiae (strain FostersB) (Baker's yeast) And more	120	UniRef50_P38902	Cluster: DNA-directed RNA polymerase II subunit RPB11	65

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	S62624 Genomic DNA. Translation: AAB27135.1. Z74747 Genomic DNA. Translation: CAA99004.1. AY557998 Genomic DNA. Translation: AAS56324.1. BK006948 Genomic DNA. Translation: DAA10778.1.
PIRⁱ	S58933.
NCBI Reference Sequences More...RefSeqⁱ	NP_014638.1. NM_001183259.1.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1I3Q	X-ray	3.10	K	1-120	[»]
	1I50	X-ray	2.80	K	1-120	[»]
	1I6H	X-ray	3.30	K	1-120	[»]
	1K83	X-ray	2.80	K	1-120	[»]
	1NIK	X-ray	4.10	K	1-120	[»]
	1NT9	X-ray	4.20	K	1-120	[»]
	1PQV	X-ray	3.80	K	1-120	[»]
	1R5U	X-ray	4.50	K	1-120	[»]
	1R9S	X-ray	4.25	K	1-120	[»]
	1R9T	X-ray	3.50	K	1-120	[»]
	1SFO	X-ray	3.61	K	1-120	[»]
	1TWA	X-ray	3.20	K	1-120	[»]
	1TWC	X-ray	3.00	K	1-120	[»]
	1TWF	X-ray	2.30	K	1-120	[»]
	1TWG	X-ray	3.30	K	1-120	[»]
	1TWH	X-ray	3.40	K	1-120	[»]
	1WCM	X-ray	3.80	K	1-120	[»]
	1Y1V	X-ray	3.80	K	1-120	[»]
	1Y1W	X-ray	4.00	K	1-120	[»]
	1Y1Y	X-ray	4.00	K	1-120	[»]
	1Y77	X-ray	4.50	K	1-120	[»]
	2B63	X-ray	3.80	K	1-120	[»]
	2B8K	X-ray	4.15	K	1-120	[»]
	2E2H	X-ray	3.95	K	1-120	[»]
	2E2I	X-ray	3.41	K	1-120	[»]
	2E2J	X-ray	3.50	K	1-120	[»]
	2JA5	X-ray	3.80	K	1-120	[»]
	2JA6	X-ray	4.00	K	1-120	[»]
	2JA7	X-ray	3.80	K/W	1-120	[»]
	2JA8	X-ray	3.80	K	1-120	[»]
	2NVQ	X-ray	2.90	K	1-120	[»]
	2NVT	X-ray	3.36	K	1-120	[»]
	2NVX	X-ray	3.60	K	1-120	[»]
	2NVY	X-ray	3.40	K	1-120	[»]
	2NVZ	X-ray	4.30	K	1-120	[»]
	2R7Z	X-ray	3.80	K	1-120	[»]
	2R92	X-ray	3.80	K	1-120	[»]
	2R93	X-ray	4.00	K	1-120	[»]
	2VUM	X-ray	3.40	K	1-120	[»]
	2YU9	X-ray	3.40	K	1-120	[»]
	3CQZ	X-ray	2.80	K	1-120	[»]
	3FKI	X-ray	3.88	K	1-120	[»]
	3GTG	X-ray	3.78	K	1-120	[»]
	3GTJ	X-ray	3.42	K	1-120	[»]
	3GTK	X-ray	3.80	K	1-120	[»]
	3GTL	X-ray	3.38	K	1-120	[»]
	3GTM	X-ray	3.80	K	1-120	[»]
	3GTO	X-ray	4.00	K	1-120	[»]
	3GTP	X-ray	3.90	K	1-120	[»]
	3GTQ	X-ray	3.80	K	1-120	[»]
	3H3V	X-ray	4.00	L	1-120	[»]
	3HOU	X-ray	3.20	K/W	1-120	[»]
	3HOV	X-ray	3.50	K	1-120	[»]
	3HOW	X-ray	3.60	K	1-120	[»]
	3HOX	X-ray	3.65	K	1-120	[»]
	3HOY	X-ray	3.40	K	1-120	[»]
	3HOZ	X-ray	3.65	K	1-120	[»]
	3I4M	X-ray	3.70	K	1-120	[»]
	3I4N	X-ray	3.90	K	1-120	[»]
	3J0K	electron microscopy	36.00	K	1-120	[»]
	3J1N	electron microscopy	16.00	K	1-120	[»]
	3K1F	X-ray	4.30	K	1-120	[»]
	3K7A	X-ray	3.80	K	1-120	[»]
3M3Y	X-ray	3.18	K	1-120	[»]
3M4O	X-ray	3.57	K	1-120	[»]
3PO2	X-ray	3.30	K	1-120	[»]
3PO3	X-ray	3.30	K	1-120	[»]
3QT1	X-ray	4.30	K	1-120	[»]
3RZD	X-ray	3.30	K	1-120	[»]
3RZO	X-ray	3.00	K	1-120	[»]
3S14	X-ray	2.85	K	1-120	[»]
3S15	X-ray	3.30	K	1-120	[»]
3S16	X-ray	3.24	K	1-120	[»]
3S17	X-ray	3.20	K	1-120	[»]
3S1M	X-ray	3.13	K	1-120	[»]
3S1N	X-ray	3.10	K	1-120	[»]
3S1Q	X-ray	3.30	K	1-120	[»]
3S1R	X-ray	3.20	K	1-120	[»]
3S2D	X-ray	3.20	K	1-120	[»]
3S2H	X-ray	3.30	K	1-120	[»]
4A3B	X-ray	3.50	K	1-120	[»]
4A3C	X-ray	3.50	K	1-120	[»]
4A3D	X-ray	3.40	K	1-120	[»]
4A3E	X-ray	3.40	K	1-120	[»]
4A3F	X-ray	3.50	K	1-120	[»]
4A3G	X-ray	3.50	K	1-120	[»]
4A3I	X-ray	3.80	K	1-120	[»]
4A3J	X-ray	3.70	K	1-120	[»]
4A3K	X-ray	3.50	K	1-120	[»]
4A3L	X-ray	3.50	K	1-120	[»]
4A3M	X-ray	3.90	K	1-120	[»]
4A93	X-ray	3.40	K	1-120	[»]
4BBR	X-ray	3.40	K	1-120	[»]
4BBS	X-ray	3.60	K	1-120	[»]
4BXX	X-ray	3.28	K	1-120	[»]
4BXZ	X-ray	4.80	K	1-120	[»]
4BY1	X-ray	3.60	K	1-120	[»]
4BY7	X-ray	3.15	K	1-120	[»]
4V1M	electron microscopy	6.60	K	1-120	[»]
4V1N	electron microscopy	7.80	K	1-120	[»]
4V1O	electron microscopy	9.70	K	1-120	[»]
4X67	X-ray	4.10	K	1-120	[»]
4X6A	X-ray	3.96	K	1-120	[»]
4Y52	X-ray	3.50	K	1-120	[»]
4Y7N	X-ray	3.30	K	1-120	[»]
5C3E	X-ray	3.70	K	1-120	[»]
5C44	X-ray	3.95	K	1-120	[»]
5C4A	X-ray	4.20	K	1-120	[»]
5C4J	X-ray	4.00	K	1-120	[»]
5C4X	X-ray	4.00	K	1-120	[»]
5FMF	electron microscopy	6.00	K	1-115	[»]
5FYW	electron microscopy	4.35	K	1-120	[»]
5FZ5	electron microscopy	8.80	K	1-120	[»]
5IP7	X-ray	3.52	K	1-115	[»]
5IP9	X-ray	3.90	K	1-115	[»]
5OT2	X-ray	3.20	K	1-120	[»]
5SVA	electron microscopy	15.30	K	1-120	[»]
5U5Q	X-ray	3.80	K	1-120	[»]
5VVR	electron microscopy	5.80	K	1-120	[»]
5VVS	electron microscopy	6.40	K	1-120	[»]
ProteinModelPortalⁱ	P38902.
SMRⁱ	P38902.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	34399. 387 interactors.
Database of interacting proteins More...DIPⁱ	DIP-937N.
IntActⁱ	P38902. 34 interactors.
Molecular INTeraction database More...MINTⁱ	P38902.
STRINGⁱ	4932.YOL005C.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P38902.
PaxDbⁱ	P38902.
PRIDEⁱ	P38902.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	YOL005C; YOL005C; YOL005C.
GeneIDⁱ	854157.
KEGGⁱ	sce:YOL005C.

Organism-specific databases

EuPathDBⁱ	FungiDB:YOL005C.
Saccharomyces Genome Database More...SGDⁱ	S000005365. RPB11.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074975.
HOGENOMⁱ	HOG000179862.
InParanoidⁱ	P38902.
KEGG Orthology (KO) More...KOⁱ	K03008.
OMAⁱ	MAGYKIA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C5QHE.

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-33422-MONOMER.
Reactomeⁱ	R-SCE-113418. Formation of the Early Elongation Complex. R-SCE-674695. RNA Polymerase II Pre-transcription Events. R-SCE-6781823. Formation of TC-NER Pre-Incision Complex. R-SCE-6782135. Dual incision in TC-NER. R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER. R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes. R-SCE-72086. mRNA Capping. R-SCE-72165. mRNA Splicing - Minor Pathway. R-SCE-73776. RNA Polymerase II Promoter Escape. R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening. R-SCE-75953. RNA Polymerase II Transcription Initiation. R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance. R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

BioCycⁱ

YEAST:G3O-33422-MONOMER.

Reactomeⁱ

R-SCE-113418. Formation of the Early Elongation Complex.
R-SCE-674695. RNA Polymerase II Pre-transcription Events.
R-SCE-6781823. Formation of TC-NER Pre-Incision Complex.
R-SCE-6782135. Dual incision in TC-NER.
R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes.
R-SCE-72086. mRNA Capping.
R-SCE-72165. mRNA Splicing - Minor Pathway.
R-SCE-73776. RNA Polymerase II Promoter Escape.
R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-SCE-75953. RNA Polymerase II Transcription Initiation.
R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

Miscellaneous databases

EvolutionaryTraceⁱ	P38902.
Protein Ontology More...PROⁱ	PR:P38902.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06926. RNAP_II_RPB11. 1 hit.
Gene3Dⁱ	3.30.1360.10. 1 hit.
InterProⁱ	View protein in InterPro IPR037685. RBP11. IPR036603. RBP11-like. IPR009025. RBP11-like_dimer. IPR008193. RNA_pol_Rpb11_13-16kDa_CS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13656. RNA_pol_L_2. 1 hit.
SUPFAMⁱ	SSF55257. SSF55257. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01154. RNA_POL_L_13KD. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RPB11_YEAST
Accessionⁱ	P38902Primary (citable) accession number: P38902 Secondary accession number(s): D6W262
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
	Last sequence update:	February 1, 1995
	Last modified:	March 28, 2018
	This is version 171 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

UniProtKB

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UniProtKB - P38902 (RPB11_YEAST)

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DNA-directed RNA polymerase II subunit RPB11

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ