P38893 (YH10_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized isomerase YHR210C
EC=5.-.-.-

Gene names

Ordered Locus Names:

YHR210C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldose epimerase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	hexose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Uncharacterized isomerase YHR210C		PRO_0000197448
Sites
	Active site	175	1	Proton donor By similarity
	Active site	306	1	Proton acceptor By similarity
	Binding site	70	1	Substrate By similarity
	Binding site	239	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	P38893 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 836E6475D3D4A1B4	FASTA	341	37,933
	10 20 30 40 50 60 MSNNKAGGEY EVITIGDAKK LQATISELGA TLLDLKVNNE SIVLGYPDIH GYISDGYNYI 70 80 90 100 110 120 GATVGRYANR IYKGMFSMED GPHQLTVNNC GNTNHSSISS FHLKKYKASK VQNPLDDLYI 130 140 150 160 170 180 VEFTLLDDRT LPNEFPGDLA VNLKYTLNVA DMTLDLEYEA KLVSGEATPI NMTNHTYFNL 190 200 210 220 230 240 NKTMDKKSIS GTEVRLCSDK SLEVSEGALI PTGKIVQRKI ATFDSSKPTI LQDDGPIYDY 250 260 270 280 290 300 AFIVDENKNL KTTDSVSVNK LVPAFKAYHP ASRLSLEVST TEPTVLFYTG DNLCDGFTPR 310 320 330 340 SGFAVEQGRY VDAINRDGWR DCVLLRRGEV YTSKTRYRFA V

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00029 Genomic DNA. Translation: AAB69737.1. AY558296 Genomic DNA. Translation: AAS56622.1. BK006934 Genomic DNA. Translation: DAA06903.1.
PIR	S48991.
RefSeq	NP_012080.3. NM_001179341.3.
3D structure databases
ProteinModelPortal	P38893.
SMR	P38893. Positions 9-341.
ModBase	Search...
Protein-protein interaction databases
STRING	4932.YHR210C.
Protocols and materials databases
DNASU	856617.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHR210C; YHR210C; YHR210C.
GeneID	856617.
KEGG	sce:YHR210C. sce:YHR212W-A.
Organism-specific databases
CYGD	YHR210c.
SGD	S000001253. YHR210C.
Phylogenomic databases
eggNOG	COG2017.
GeneTree	ENSGT00510000047589.
HOGENOM	HOG000000863.
OMA	NWGATIL.
OrthoDB	EOG4N8VD8.
Gene expression databases
Genevestigator	P38893.
GermOnline	YHR210C. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	982547.

Entry information

Entry name

YH10_YEAST

Accession

Primary (citable) accession number: P38893
Secondary accession number(s): D3DLF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 98 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program