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Protein

Uncharacterized isomerase YHR210C

Gene

YHR210C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei70 – 701SubstrateBy similarity
Active sitei175 – 1751Proton donorPROSITE-ProRule annotation
Binding sitei239 – 2391SubstrateBy similarity
Active sitei306 – 3061Proton acceptorBy similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Enzyme and pathway databases

BioCyciYEAST:G3O-31235-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized isomerase YHR210C (EC:5.-.-.-)
Gene namesi
Ordered Locus Names:YHR210C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR210c.
SGDiS000001253. YHR210C.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 341341Uncharacterized isomerase YHR210CPRO_0000197448Add
BLAST

Proteomic databases

MaxQBiP38893.

Expressioni

Gene expression databases

GenevestigatoriP38893.

Interactioni

Protein-protein interaction databases

BioGridi36644. 12 interactions.
STRINGi4932.YHR210C.

Structurei

3D structure databases

ProteinModelPortaliP38893.
SMRiP38893. Positions 9-341.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.Curated

Phylogenomic databases

eggNOGiCOG2017.
GeneTreeiENSGT00510000047589.
HOGENOMiHOG000000863.
InParanoidiP38893.
OMAiQPEWGID.
OrthoDBiEOG77T1F2.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38893-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNNKAGGEY EVITIGDAKK LQATISELGA TLLDLKVNNE SIVLGYPDIH
60 70 80 90 100
GYISDGYNYI GATVGRYANR IYKGMFSMED GPHQLTVNNC GNTNHSSISS
110 120 130 140 150
FHLKKYKASK VQNPLDDLYI VEFTLLDDRT LPNEFPGDLA VNLKYTLNVA
160 170 180 190 200
DMTLDLEYEA KLVSGEATPI NMTNHTYFNL NKTMDKKSIS GTEVRLCSDK
210 220 230 240 250
SLEVSEGALI PTGKIVQRKI ATFDSSKPTI LQDDGPIYDY AFIVDENKNL
260 270 280 290 300
KTTDSVSVNK LVPAFKAYHP ASRLSLEVST TEPTVLFYTG DNLCDGFTPR
310 320 330 340
SGFAVEQGRY VDAINRDGWR DCVLLRRGEV YTSKTRYRFA V
Length:341
Mass (Da):37,933
Last modified:February 1, 1995 - v1
Checksum:i836E6475D3D4A1B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00029 Genomic DNA. Translation: AAB69737.1.
AY558296 Genomic DNA. Translation: AAS56622.1.
BK006934 Genomic DNA. Translation: DAA06903.1.
PIRiS48991.
RefSeqiNP_012080.3. NM_001179341.3.

Genome annotation databases

EnsemblFungiiYHR210C; YHR210C; YHR210C.
GeneIDi856617.
KEGGisce:YHR210C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00029 Genomic DNA. Translation: AAB69737.1.
AY558296 Genomic DNA. Translation: AAS56622.1.
BK006934 Genomic DNA. Translation: DAA06903.1.
PIRiS48991.
RefSeqiNP_012080.3. NM_001179341.3.

3D structure databases

ProteinModelPortaliP38893.
SMRiP38893. Positions 9-341.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36644. 12 interactions.
STRINGi4932.YHR210C.

Proteomic databases

MaxQBiP38893.

Protocols and materials databases

DNASUi856617.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR210C; YHR210C; YHR210C.
GeneIDi856617.
KEGGisce:YHR210C.

Organism-specific databases

CYGDiYHR210c.
SGDiS000001253. YHR210C.

Phylogenomic databases

eggNOGiCOG2017.
GeneTreeiENSGT00510000047589.
HOGENOMiHOG000000863.
InParanoidiP38893.
OMAiQPEWGID.
OrthoDBiEOG77T1F2.

Enzyme and pathway databases

BioCyciYEAST:G3O-31235-MONOMER.

Miscellaneous databases

NextBioi982547.

Gene expression databases

GenevestigatoriP38893.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiYH10_YEAST
AccessioniPrimary (citable) accession number: P38893
Secondary accession number(s): D3DLF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: January 7, 2015
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.