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Protein

Altered inheritance of mitochondria protein 18, mitochondrial

Gene

AIM18

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31226-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Altered inheritance of mitochondria protein 18, mitochondrial
Alternative name(s):
Found in mitochondrial proteome protein 22
Gene namesi
Name:AIM18
Synonyms:FMP22
Ordered Locus Names:YHR198C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR198C.
SGDiS000001241. AIM18.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Disruption phenotypei

Increases frequency of mitochondrial genome loss.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 72MitochondrionSequence analysisAdd BLAST72
ChainiPRO_000020293973 – 321Altered inheritance of mitochondria protein 18, mitochondrialAdd BLAST249

Proteomic databases

MaxQBiP38884.
PRIDEiP38884.

Interactioni

Protein-protein interaction databases

BioGridi36632. 37 interactors.
DIPiDIP-1697N.
IntActiP38884. 2 interactors.
MINTiMINT-392543.

Structurei

3D structure databases

ProteinModelPortaliP38884.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIM18/AIM46 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00530000066708.
HOGENOMiHOG000066115.
InParanoidiP38884.
OMAiIACAVRI.
OrthoDBiEOG092C4ERF.

Family and domain databases

InterProiIPR016087. Chalcone_isomerase.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P38884-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRGRCANML KSLQRTLAKC QKSPSTNHWQ CFKRNFTSIR ATKYPGRSNS
60 70 80 90 100
TFHYWPWFAA STLLATSLYY RDRPVQNDDK TDAFPSHTES IQVDSSVSDF
110 120 130 140 150
PLTITALNFP VSTTFKLLGY GQRHVTFLRF KVYALGLYLA ENDENLVSDT
160 170 180 190 200
LNETYLHKYF LDVDDSKTPK ENLARLLKRD DSKSVMMIDD LLDSGMRMLA
210 220 230 240 250
KITPVRNTDF KHLKEGLVKT ISKHPDVANN KDTLAKGLSE LNDAFSRKGS
260 270 280 290 300
VRKNDDLIIE LLANGALQFS YHDSKNNEFE VMGVVNNQLV GKFLFSQYLC
310 320
GEKSPSPQAK KTAIDKLITL L
Length:321
Mass (Da):36,502
Last modified:February 1, 1995 - v1
Checksum:iA6C07E03AE1EEC80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00030 Genomic DNA. Translation: AAB68373.1.
AY558106 Genomic DNA. Translation: AAS56432.1.
BK006934 Genomic DNA. Translation: DAA06890.1.
PIRiS46690.
RefSeqiNP_012068.1. NM_001179329.1.

Genome annotation databases

EnsemblFungiiYHR198C; YHR198C; YHR198C.
GeneIDi856605.
KEGGisce:YHR198C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00030 Genomic DNA. Translation: AAB68373.1.
AY558106 Genomic DNA. Translation: AAS56432.1.
BK006934 Genomic DNA. Translation: DAA06890.1.
PIRiS46690.
RefSeqiNP_012068.1. NM_001179329.1.

3D structure databases

ProteinModelPortaliP38884.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36632. 37 interactors.
DIPiDIP-1697N.
IntActiP38884. 2 interactors.
MINTiMINT-392543.

Proteomic databases

MaxQBiP38884.
PRIDEiP38884.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR198C; YHR198C; YHR198C.
GeneIDi856605.
KEGGisce:YHR198C.

Organism-specific databases

EuPathDBiFungiDB:YHR198C.
SGDiS000001241. AIM18.

Phylogenomic databases

GeneTreeiENSGT00530000066708.
HOGENOMiHOG000066115.
InParanoidiP38884.
OMAiIACAVRI.
OrthoDBiEOG092C4ERF.

Enzyme and pathway databases

BioCyciYEAST:G3O-31226-MONOMER.

Miscellaneous databases

PROiP38884.

Family and domain databases

InterProiIPR016087. Chalcone_isomerase.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAIM18_YEAST
AccessioniPrimary (citable) accession number: P38884
Secondary accession number(s): D3DLE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1350 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.