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Protein

U3 small nucleolar RNA-associated protein 9

Gene

UTP9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).2 Publications

GO - Molecular functioni

  • snoRNA binding Source: SGD

GO - Biological processi

  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD
  • positive regulation of transcription from RNA polymerase I promoter Source: SGD
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing, Transcription

Enzyme and pathway databases

BioCyciYEAST:G3O-31224-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 9
Short name:
U3 snoRNA-associated protein 9
Alternative name(s):
U three protein 9
U3 protein 9 required for transcription
t-UTP9
Gene namesi
Name:UTP9
Ordered Locus Names:YHR196W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR196W.
SGDiS000001239. UTP9.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: SGD
  • rDNA heterochromatin Source: SGD
  • small-subunit processome Source: SGD
  • t-UTP complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000657441 – 575U3 small nucleolar RNA-associated protein 9Add BLAST575

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei547PhosphoserineCombined sources1
Modified residuei564PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP38882.
PRIDEiP38882.

PTM databases

iPTMnetiP38882.

Interactioni

Subunit structurei

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. In the absence of snoRNA3, forms a complex with other t-UTPs. This complex can associate with pre-18S ribosomal RNAs.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
UTP15Q043054EBI-24892,EBI-28183
UTP8P532763EBI-24892,EBI-23301

Protein-protein interaction databases

BioGridi36630. 101 interactors.
DIPiDIP-6634N.
IntActiP38882. 55 interactors.
MINTiMINT-628324.

Structurei

3D structure databases

ProteinModelPortaliP38882.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000000891.
InParanoidiP38882.
KOiK14551.
OMAiNVNEPNF.
OrthoDBiEOG092C1L1X.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P38882-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSSLDLVAS FSHDSTRFAF QASVAQKNNV DIYPLNETKD YVVNSSLVSH
60 70 80 90 100
IDYETNDMKV SDVIFFGWCS DLIDTQSSNI KRKLDEDEGT GESSEQRCEN
110 120 130 140 150
FFVNGFPDGR IVVYSSNGKD IVNIIKNKKE ILGADTDESD IWILDSDKVV
160 170 180 190 200
KKLQYNNSKP LKTFTLVDGK DDEIVHFQIL HQNGTLLVCI ITKQMVYIVD
210 220 230 240 250
PSKRRPSTKY SFEISDAVAC EFSSDGKYLL IANNEELIAY DLKEDSKLIQ
260 270 280 290 300
SWPVQVKTLK TLDDLIMALT TDGKINNYKI GEADKVCSIV VNEDLEIIDF
310 320 330 340 350
TPINSKQQVL ISWLNVNEPN FESISLKEIE TQGYITINKN EKNNADEADQ
360 370 380 390 400
KKLEEKEEEA QPEVQHEKKE TETKINKKVS KSDQVEIANI LSSHLEANST
410 420 430 440 450
EILDDLMSGS WTEPEIKKFI LTKINTVDHL SKIFLTISKS ITQNPWNEEN
460 470 480 490 500
LLPLWLKWLL TLKSGELNSI KDKHTKKNCK HLKSALRSSE EILPVLLGIQ
510 520 530 540 550
GRLEMLRRQA KLREDLAQLS MQEGEDDEIE VIEHSNVISN PLQDQASPVE
560 570
KLEPDSIVYA NGESDEFVDA SEYKD
Length:575
Mass (Da):65,271
Last modified:February 1, 1995 - v1
Checksum:i0C482C6A32855FF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00030 Genomic DNA. Translation: AAB68369.1.
BK006934 Genomic DNA. Translation: DAA06888.1.
PIRiS46692.
RefSeqiNP_012066.1. NM_001179327.1.

Genome annotation databases

EnsemblFungiiYHR196W; YHR196W; YHR196W.
GeneIDi856603.
KEGGisce:YHR196W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00030 Genomic DNA. Translation: AAB68369.1.
BK006934 Genomic DNA. Translation: DAA06888.1.
PIRiS46692.
RefSeqiNP_012066.1. NM_001179327.1.

3D structure databases

ProteinModelPortaliP38882.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36630. 101 interactors.
DIPiDIP-6634N.
IntActiP38882. 55 interactors.
MINTiMINT-628324.

PTM databases

iPTMnetiP38882.

Proteomic databases

MaxQBiP38882.
PRIDEiP38882.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHR196W; YHR196W; YHR196W.
GeneIDi856603.
KEGGisce:YHR196W.

Organism-specific databases

EuPathDBiFungiDB:YHR196W.
SGDiS000001239. UTP9.

Phylogenomic databases

HOGENOMiHOG000000891.
InParanoidiP38882.
KOiK14551.
OMAiNVNEPNF.
OrthoDBiEOG092C1L1X.

Enzyme and pathway databases

BioCyciYEAST:G3O-31224-MONOMER.

Miscellaneous databases

PROiP38882.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUTP9_YEAST
AccessioniPrimary (citable) accession number: P38882
Secondary accession number(s): D3DLE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 20000 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.