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P38872 (ADY1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Prospore formation at selected spindle poles protein 1
Alternative name(s):
Accumulates dyads protein 1
Gene names
Name:PFS1
Synonyms:ADY1
Ordered Locus Names:YHR185C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required to localize MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to four prospore membranes. Ref.3

Subcellular location

Nucleus. Cytoplasmcytoskeletonmicrotubule organizing centerspindle pole body. Note: Nuclear in mononucleate meiotic cells. May not be localized to the spindle pole body or prospore membrane. Ref.3

Ontologies

Keywords
   Biological processSporulation
   Cellular componentCytoplasm
Cytoskeleton
Nucleus
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processascospore wall assembly

Inferred from mutant phenotype Ref.3. Source: SGD

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

spindle pole body

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

HRR25P292953EBI-24859,EBI-8536
NAS2P405553EBI-24859,EBI-14024

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Prospore formation at selected spindle poles protein 1
PRO_0000064460

Sequences

Sequence LengthMass (Da)Tools
P38872 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 027F01058C0CFE6E

FASTA23727,884
        10         20         30         40         50         60 
MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT FPEFNPALRR 

        70         80         90        100        110        120 
RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL PNPYLSYLNH IEKVNCQDVK 

       130        140        150        160        170        180 
FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC SEKVESWLER LPIFVGFDGY LFTNCFDYEY 

       190        200        210        220        230 
MLDWEETEFT FEKTSCMETD YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae."
Deng C., Saunders W.S.
Mol. Biol. Cell 12:2646-2659(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00030 Genomic DNA. Translation: AAB68363.1.
BK006934 Genomic DNA. Translation: DAA06877.1.
PIRS46685.
RefSeqNP_012055.3. NM_001179316.3.

3D structure databases

ProteinModelPortalP38872.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36618. 46 interactions.
DIPDIP-1372N.
IntActP38872. 6 interactions.
MINTMINT-394703.
STRING4932.YHR185C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR185C; YHR185C; YHR185C.
GeneID856591.
KEGGsce:YHR185C.

Organism-specific databases

CYGDYHR185c.
SGDS000001228. PFS1.

Phylogenomic databases

eggNOGNOG69411.
OrthoDBEOG780RZ1.

Enzyme and pathway databases

BioCycYEAST:G3O-31215-MONOMER.

Gene expression databases

GenevestigatorP38872.

Family and domain databases

ProtoNetSearch...

Other

NextBio982470.

Entry information

Entry nameADY1_YEAST
AccessionPrimary (citable) accession number: P38872
Secondary accession number(s): D3DLD3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD