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P38872

- ADY1_YEAST

UniProt

P38872 - ADY1_YEAST

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Protein
Prospore formation at selected spindle poles protein 1
Gene
PFS1, ADY1, YHR185C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required to localize MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to four prospore membranes.1 Publication

GO - Molecular functioni

  1. protein binding Source: IntAct

GO - Biological processi

  1. ascospore wall assembly Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sporulation

Enzyme and pathway databases

BioCyciYEAST:G3O-31215-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Prospore formation at selected spindle poles protein 1
Alternative name(s):
Accumulates dyads protein 1
Gene namesi
Name:PFS1
Synonyms:ADY1
Ordered Locus Names:YHR185C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VIII

Organism-specific databases

CYGDiYHR185c.
SGDiS000001228. PFS1.

Subcellular locationi

Nucleus. Cytoplasmcytoskeletonmicrotubule organizing centerspindle pole body
Note: Nuclear in mononucleate meiotic cells. May not be localized to the spindle pole body or prospore membrane.1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
  3. spindle pole body Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237Prospore formation at selected spindle poles protein 1
PRO_0000064460Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP38872.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HRR25P292953EBI-24859,EBI-8536
NAS2P405553EBI-24859,EBI-14024

Protein-protein interaction databases

BioGridi36618. 46 interactions.
DIPiDIP-1372N.
IntActiP38872. 6 interactions.
MINTiMINT-394703.
STRINGi4932.YHR185C.

Structurei

3D structure databases

ProteinModelPortaliP38872.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG69411.
OrthoDBiEOG780RZ1.

Sequencei

Sequence statusi: Complete.

P38872-1 [UniParc]FASTAAdd to Basket

« Hide

MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT    50
FPEFNPALRR RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL 100
PNPYLSYLNH IEKVNCQDVK FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC 150
SEKVESWLER LPIFVGFDGY LFTNCFDYEY MLDWEETEFT FEKTSCMETD 200
YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF 237
Length:237
Mass (Da):27,884
Last modified:February 1, 1995 - v1
Checksum:i027F01058C0CFE6E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00030 Genomic DNA. Translation: AAB68363.1.
BK006934 Genomic DNA. Translation: DAA06877.1.
PIRiS46685.
RefSeqiNP_012055.3. NM_001179316.3.

Genome annotation databases

EnsemblFungiiYHR185C; YHR185C; YHR185C.
GeneIDi856591.
KEGGisce:YHR185C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00030 Genomic DNA. Translation: AAB68363.1 .
BK006934 Genomic DNA. Translation: DAA06877.1 .
PIRi S46685.
RefSeqi NP_012055.3. NM_001179316.3.

3D structure databases

ProteinModelPortali P38872.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36618. 46 interactions.
DIPi DIP-1372N.
IntActi P38872. 6 interactions.
MINTi MINT-394703.
STRINGi 4932.YHR185C.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YHR185C ; YHR185C ; YHR185C .
GeneIDi 856591.
KEGGi sce:YHR185C.

Organism-specific databases

CYGDi YHR185c.
SGDi S000001228. PFS1.

Phylogenomic databases

eggNOGi NOG69411.
OrthoDBi EOG780RZ1.

Enzyme and pathway databases

BioCyci YEAST:G3O-31215-MONOMER.

Miscellaneous databases

NextBioi 982470.

Gene expression databases

Genevestigatori P38872.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae."
    Deng C., Saunders W.S.
    Mol. Biol. Cell 12:2646-2659(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiADY1_YEAST
AccessioniPrimary (citable) accession number: P38872
Secondary accession number(s): D3DLD3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: June 11, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

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