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P38872

- ADY1_YEAST

UniProt

P38872 - ADY1_YEAST

Protein

Prospore formation at selected spindle poles protein 1

Gene

PFS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required to localize MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to four prospore membranes.1 Publication

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. ascospore wall assembly Source: SGD

    Keywords - Biological processi

    Sporulation

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31215-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Prospore formation at selected spindle poles protein 1
    Alternative name(s):
    Accumulates dyads protein 1
    Gene namesi
    Name:PFS1
    Synonyms:ADY1
    Ordered Locus Names:YHR185C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHR185c.
    SGDiS000001228. PFS1.

    Subcellular locationi

    Nucleus 1 Publication. Cytoplasmcytoskeletonmicrotubule organizing centerspindle pole body 1 Publication
    Note: Nuclear in mononucleate meiotic cells. May not be localized to the spindle pole body or prospore membrane.

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell
    3. spindle pole body Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237Prospore formation at selected spindle poles protein 1PRO_0000064460Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP38872.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    HRR25P292953EBI-24859,EBI-8536
    NAS2P405553EBI-24859,EBI-14024

    Protein-protein interaction databases

    BioGridi36618. 46 interactions.
    DIPiDIP-1372N.
    IntActiP38872. 6 interactions.
    MINTiMINT-394703.
    STRINGi4932.YHR185C.

    Structurei

    3D structure databases

    ProteinModelPortaliP38872.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG69411.
    OrthoDBiEOG780RZ1.

    Sequencei

    Sequence statusi: Complete.

    P38872-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT    50
    FPEFNPALRR RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL 100
    PNPYLSYLNH IEKVNCQDVK FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC 150
    SEKVESWLER LPIFVGFDGY LFTNCFDYEY MLDWEETEFT FEKTSCMETD 200
    YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF 237
    Length:237
    Mass (Da):27,884
    Last modified:February 1, 1995 - v1
    Checksum:i027F01058C0CFE6E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00030 Genomic DNA. Translation: AAB68363.1.
    BK006934 Genomic DNA. Translation: DAA06877.1.
    PIRiS46685.
    RefSeqiNP_012055.3. NM_001179316.3.

    Genome annotation databases

    EnsemblFungiiYHR185C; YHR185C; YHR185C.
    GeneIDi856591.
    KEGGisce:YHR185C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00030 Genomic DNA. Translation: AAB68363.1 .
    BK006934 Genomic DNA. Translation: DAA06877.1 .
    PIRi S46685.
    RefSeqi NP_012055.3. NM_001179316.3.

    3D structure databases

    ProteinModelPortali P38872.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36618. 46 interactions.
    DIPi DIP-1372N.
    IntActi P38872. 6 interactions.
    MINTi MINT-394703.
    STRINGi 4932.YHR185C.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHR185C ; YHR185C ; YHR185C .
    GeneIDi 856591.
    KEGGi sce:YHR185C.

    Organism-specific databases

    CYGDi YHR185c.
    SGDi S000001228. PFS1.

    Phylogenomic databases

    eggNOGi NOG69411.
    OrthoDBi EOG780RZ1.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31215-MONOMER.

    Miscellaneous databases

    NextBioi 982470.

    Gene expression databases

    Genevestigatori P38872.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae."
      Deng C., Saunders W.S.
      Mol. Biol. Cell 12:2646-2659(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiADY1_YEAST
    AccessioniPrimary (citable) accession number: P38872
    Secondary accession number(s): D3DLD3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3