Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P38863 (SPC97_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Spindle pole body component SPC97
Gene names
Name:SPC97
Ordered Locus Names:YHR172W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length823 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in microtubule organization by the microtubule organizing center, the spindle pole body (SPB). Probably part of the microtubule attachment site at the SPB.

Subunit structure

Interacts with TUB4, SPC72 and SPC98. Ref.4

Subcellular location

Nucleus. Cytoplasmcytoskeletonmicrotubule organizing centerspindle pole body.

Miscellaneous

Present with 2230 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the TUBGCP family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SPC98P535403EBI-17786,EBI-17794
TUB4P533784EBI-17786,EBI-19013

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 823823Spindle pole body component SPC97
PRO_0000078117

Sequences

Sequence LengthMass (Da)Tools
P38863 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: A3F7018957D96E8D

FASTA82396,825
        10         20         30         40         50         60 
MEIKEVDDRA ELLRYTNNIP LLGKLVNHQP LWSTNPKLKS FSLEKISAPD QRRVQEALVV 

        70         80         90        100        110        120 
KDLLNVLIGL EGTYIRYFND YEPSDPETPI EFKIAKKMDP SFKTFSRRIV RYGKQYMILT 

       130        140        150        160        170        180 
RAYEKWSDTS FGMVLQRFAY EIRRFLEDVY LKTLVERLER DFNKVPNFSI RELEQIINET 

       190        200        210        220        230        240 
EVNKQMELLY NIYEEIFREI EERRTNQSSQ EDFNNFMDSM KNESSLHLRL MVAFDTTVYP 

       250        260        270        280        290        300 
VPKGGAILKI FQQKILENLG DRSSVMFLKK LLNNISQDYC TMLYEWLTQG ILNDPYQEFM 

       310        320        330        340        350        360 
TYDDLEGKTD NIFDTRDRAW DTQYFIRKDV LLRDCDSEED KNLLFKMLRT GILLKVVRAS 

       370        380        390        400        410        420 
LQIPTIPSNS SDITIQEIND FADLMEGSNL ELYVDKCYSR ANEIFLKLFF QGYDLINVLK 

       430        440        450        460        470        480 
HLQQIFLGYQ SGHNVLKFLT KNMGELTKHY RNDNNANYDK LLQNFELERQ SENPNNLMRQ 

       490        500        510        520        530        540 
LLMIQFDTET LPQVLSHYLQ IYPEVPENNS ANDDSDPLMH ANNFKNMNAI LFDELSKERT 

       550        560        570        580        590        600 
GAYHGSNLEL YTPKSAIYHL KFDINIPYPL NIIISRTCMI KYQIILRYQL VLQYHSRLLD 

       610        620        630        640        650        660 
ETWMDLNKTP SWKYRGYSHT VKRRIVRATR VLHAKMNHFI KTIMEYFNQN VIDKEVYSLE 

       670        680        690        700        710        720 
KCYRNPTLAV AIQNELEGGL TNIMTNRCLS DLIPLQLQIF DIVYKFCKFI KSMRAKLCQL 

       730        740        750        760        770        780 
DPVLYEKHKS GMMKTLNEGY RTNNGGQEDV GYQEDAALEL IQKLIEYISN ASSIFRKCLI 

       790        800        810        820 
NFTQELSTEK FDFYDSSSVD AAGIERVLYS IVPPRSASAS SQR 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"The spindle pole body component Spc97p interacts with the gamma-tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplication."
Knop M., Pereira G., Geissler S., Grein K., Schiebel E.
EMBO J. 16:1550-1564(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
[4]"Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation."
Knop M., Schiebel E.
EMBO J. 17:3952-3967(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH SPC72.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00027 Genomic DNA. Translation: AAB68017.1.
BK006934 Genomic DNA. Translation: DAA06865.1.
PIRS48911.
RefSeqNP_012042.1. NM_001179303.1.

3D structure databases

ProteinModelPortalP38863.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36606. 17 interactions.
DIPDIP-826N.
IntActP38863. 14 interactions.
MINTMINT-477633.
STRING4932.YHR172W.

Proteomic databases

MaxQBP38863.
PaxDbP38863.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR172W; YHR172W; YHR172W.
GeneID856577.
KEGGsce:YHR172W.

Organism-specific databases

CYGDYHR172w.
SGDS000001215. SPC97.

Phylogenomic databases

eggNOGKOG2001.
HOGENOMHOG000144398.
KOK16569.
OMARANKLLM.
OrthoDBEOG77Q554.

Enzyme and pathway databases

BioCycYEAST:G3O-31206-MONOMER.

Gene expression databases

GenevestigatorP38863.

Family and domain databases

InterProIPR007259. TUBGCP.
[Graphical view]
PANTHERPTHR19302. PTHR19302. 1 hit.
PfamPF04130. Spc97_Spc98. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio982435.
PROP38863.

Entry information

Entry nameSPC97_YEAST
AccessionPrimary (citable) accession number: P38863
Secondary accession number(s): D3DLC1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 9, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families