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P38858

- SOL3_YEAST

UniProt

P38858 - SOL3_YEAST

Protein

6-phosphogluconolactonase 3

Gene

SOL3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 113 (01 Oct 2014)
      Sequence version 2 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.1 Publication

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: SGD

    GO - Biological processi

    1. pentose-phosphate shunt, oxidative branch Source: SGD

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciYEAST:MONOMER3O-4032.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonase 3 (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    Name:SOL3
    Ordered Locus Names:YHR163W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    SGDiS000001206. SOL3.

    Subcellular locationi

    Cytoplasm 1 Publication. Nucleus 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2492496-phosphogluconolactonase 3PRO_0000090084Add
    BLAST

    Proteomic databases

    MaxQBiP38858.
    PaxDbiP38858.
    PeptideAtlasiP38858.

    Expressioni

    Gene expression databases

    GenevestigatoriP38858.

    Interactioni

    Protein-protein interaction databases

    BioGridi36597. 41 interactions.
    DIPiDIP-5625N.
    IntActiP38858. 1 interaction.
    MINTiMINT-508230.
    STRINGi4932.YHR163W.

    Structurei

    3D structure databases

    ProteinModelPortaliP38858.
    SMRiP38858. Positions 19-238.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    GeneTreeiENSGT00550000075110.
    HOGENOMiHOG000256285.
    KOiK01057.
    OMAiERVCAWE.
    OrthoDBiEOG7MD51D.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P38858-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVTVGVFSER ASLTHQLGEF IVKKQDEALQ KKSDFKVSVS GGSLIDALYE    50
    SLVADESLSS RVQWSKWQIY FSDERIVPLT DADSNYGAFK RAVLDKLPST 100
    SQPNVYPMDE SLIGSDAESN NKIAAEYERI VPQVLDLVLL GCGPDGHTCS 150
    LFPGETHRYL LNETTKRVAW CHDSPKPPSD RITFTLPVLK DAKALCFVAE 200
    GSSKQNIMHE IFDLKNDQLP TALVNKLFGE KTSWFVNEEA FGKVQTKTF 249
    Length:249
    Mass (Da):27,784
    Last modified:June 16, 2009 - v2
    Checksum:iF19B313390EA6B3D
    GO

    Sequence cautioni

    The sequence AAB49323.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAB68008.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U46560 Genomic DNA. Translation: AAB49323.1. Different initiation.
    U00027 Genomic DNA. Translation: AAB68008.1. Different initiation.
    BK006934 Genomic DNA. Translation: DAA06856.1.
    PIRiS48903.
    RefSeqiNP_012033.2. NM_001179294.1.

    Genome annotation databases

    EnsemblFungiiYHR163W; YHR163W; YHR163W.
    GeneIDi856568.
    KEGGisce:YHR163W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U46560 Genomic DNA. Translation: AAB49323.1 . Different initiation.
    U00027 Genomic DNA. Translation: AAB68008.1 . Different initiation.
    BK006934 Genomic DNA. Translation: DAA06856.1 .
    PIRi S48903.
    RefSeqi NP_012033.2. NM_001179294.1.

    3D structure databases

    ProteinModelPortali P38858.
    SMRi P38858. Positions 19-238.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36597. 41 interactions.
    DIPi DIP-5625N.
    IntActi P38858. 1 interaction.
    MINTi MINT-508230.
    STRINGi 4932.YHR163W.

    Proteomic databases

    MaxQBi P38858.
    PaxDbi P38858.
    PeptideAtlasi P38858.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHR163W ; YHR163W ; YHR163W .
    GeneIDi 856568.
    KEGGi sce:YHR163W.

    Organism-specific databases

    SGDi S000001206. SOL3.

    Phylogenomic databases

    eggNOGi COG0363.
    GeneTreei ENSGT00550000075110.
    HOGENOMi HOG000256285.
    KOi K01057.
    OMAi ERVCAWE.
    OrthoDBi EOG7MD51D.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci YEAST:MONOMER3O-4032.

    Miscellaneous databases

    NextBioi 982408.
    PROi P38858.

    Gene expression databases

    Genevestigatori P38858.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family."
      Shen W.-C., Stanford D.R., Hopper A.K.
      Genetics 143:699-712(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
      Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
      Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism."
      Stanford D.R., Whitney M.L., Hurto R.L., Eisaman D.M., Shen W.-C., Hopper A.K.
      Genetics 168:117-127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    8. "Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE."
      Zhang Z., Dietrich F.S.
      Nucleic Acids Res. 33:2838-2851(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSOL3_YEAST
    AccessioniPrimary (citable) accession number: P38858
    Secondary accession number(s): D3DLB2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 113 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 3420 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3